- Search results for K05704
Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
163 products were found matching "K05704"!
Close filters
Filter by:
No results were found for the filter!
Item number: Cay10954-10
1-NA-PP1 is a reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase. 1-NA-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over...
Keywords: | 1-Naphthyl-PP1, PP1 Analog, 1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
CAS | 221243-82-9 |
MW: | 317.4 D |
From 31.00€
*
Item number: NSJ-RQ5396
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. The SRC gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose...
Keywords: | Anti-SRC1, Anti-p60-Src, Anti-pp60c-src, Anti-Proto-oncogene c-Src, Anti-Proto-oncogene tyrosine-protein kinase Src, Src... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
755.00€
*
Item number: NSJ-RQ5397
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. The SRC gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose...
Keywords: | Anti-SRC1, Anti-p60-Src, Anti-pp60c-src, Anti-Proto-oncogene c-Src, Anti-Proto-oncogene tyrosine-protein kinase Src, Src... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
755.00€
*
Item number: Cay21089-10
CGP 77675 is an inhibitor of Src family kinases (SFKs) that blocks the phosphorylation of peptide substrates and autophosphorylation of purified c-Src (IC50s = 5-20 and 40 nM, respectively). It also inhibits the SFKs Lck and c-Yes with low nanomolar IC50 values. CGP 77675 is used to elucidate the role of SFKs in...
Keywords: | 1-[2-[4-[4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]phenyl]ethyl]-4-piperidinol |
Application: | Src inhibitor |
MW: | 443.5 D |
From 52.00€
*
Item number: Cay12030-5
Bosutinib is an inhibitor of c-Src and Abl kinases (IC50s = 1.2 and 1 nM, respectively). It also inhibits the kinases EPHB2, TrkA, TrkB, and TXK (IC50s = 8.5, 22, 27, and 40 nM, respectively) among others. Bosutinib inhibits Src-dependent cell proliferation (IC50 = 100 nM) and reverses Src-transformed fibroblasts to...
Keywords: | SKI 606, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile |
Application: | c-Src and Abl inhibitor |
CAS | 380843-75-4 |
MW: | 530.5 D |
From 60.00€
*
Item number: Cay11498-50
Dasatinib is a potent inhibitor of the non-receptor tyrosine kinases Abl and Src as well as other members of the Src family. It is effective at sub-nanomolar concentrations, inhibiting Src, Abl, and Lck with IC50 values of 0.05, 0.5, and 0.4 nM, respectively. At nanomolar concentrations, dasatinib also blocks the...
Keywords: | BMS 354825, Sprycel,... |
Application: | Tyrosine kinase inhibitor |
CAS | 302962-49-8 |
MW: | 488 D |
From 43.00€
*
Item number: Cay13338-5
The Src family of proto-oncogenic kinases include nine mammalian non-receptor tyrosine kinases that are involved in intracellular signaling and are often relevant to carcinogenesis. SU6656 is a selective inhibitor of Src kinases, Including Src, Yes, Lyn, and Fyn (IC50 = 280, 20, 130, 170 nM, respectively). It weakly...
Keywords: | 2,3-dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide |
Application: | Src kinase inhibitor |
CAS | 330161-87-0 |
MW: | 371.5 D |
From 32.00€
*
Item number: Cay26911-1
Altenusin is a polyphenol fungal metabolite originally isolated from the fungus Alternaria that has diverse biological activities. It inhibits Src kinase with an IC50 value of 20 nM. Altenusin inhibits fibrillization of recombinant tau fragments in vitro and phosphorylation of tau in SH-SY5Y cells expressing human...
Keywords: | Alutenusin, 3,4',5'-trihydroxy-5-methoxy-2'-methyl-[1,1'-biphenyl]-2-carboxylic acid |
Application: | Bioactive polyphenol fungal metabolite, Src inhibitor |
CAS | 31186-12-6 |
MW: | 290.3 D |
From 100.00€
*
Item number: BPS-40483
Active human SRC (GenBank Accession No. NM_005417), full length with N-terminal GST tag, MW = 86 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Keywords: | SRC1, p60-Src, pp60c-src, Proto-oncogene c-Src, Proto-oncogene tyrosine-protein kinase Src, |
Application: | Enzyme kinetics, inhibitor screening |
MW: | 86 kD |
525.00€
*
Item number: Cay15595-1
The Src family of non-receptor tyrosine kinases regulate cell adhesion, growth, and differentiation through activation of multiple intracellular signaling pathways. Normally inactive, Src kinases are transiently activated during mitosis and constitutively activated by abnormal mutations. Several small molecule...
Keywords: | NSC 1401, 1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
Application: | Inactive Src tyrosine kinase inhibitor analog |
CAS | 5334-30-5 |
MW: | 211.2 D |
From 77.00€
*
Item number: Cay21429-5
KX2-391 is an inhibitor of Src kinase (IC50 = ~20 nM). It is selective for Src over PDGFR, EGFR, JAK1, JAK2, Lck, and ZAP-70. KX2-391 induces cell cycle arrest at the G2/M phase and apoptosis in breast cancer cells expressing estrogen receptor alpha (ERalpha). It inhibits the growth of Huh7, PLC/PRF/5, Hep3B, and...
Keywords: | KX 01, 5-[4-[2-(4-morpholinyl)ethoxy]phenyl]-N-(phenylmethyl)-2-pyridineacetamide |
Application: | Src kinase inhibitor |
CAS | 897016-82-9 |
MW: | 431.5 D |
From 130.00€
*
Item number: 0080-100
Does not cross-react with the non-phosphorylated form of src or with unrelated phosphorylation sites.
Keywords: | (pY416) EC=2.7.10.2, Anti-phospho-SRC, Anti-phospho-SRC1, Anti-phospho-p60-Src, Anti-phospho-pp60c-src,... |
Application: | WB, ELISA, ICC, FC |
Host: | Mouse |
Species reactivity: | human, mouse |
383.00€
*