AG-14361

Item number	Size	Manual	SDS	Delivery time	Price
BPS-27602-1	5 mg	-	-	3 - 15 business days*	453.00€
BPS-27602-2	10 mg	-	-	3 - 15 business days*	774.00€
BPS-27602-3	50 mg	-	-	3 - 15 business days*	1,749.00€

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AG14361 is a potent inhibitor of PARP1 with Ki of <5 nM. It is at least 1000-fold more potent... more

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Product information "AG-14361"

AG14361 is a potent inhibitor of PARP1 with Ki of <5 nM. It is at least 1000-fold more potent than the benzamides. AG14361 treatment before irradiation statistically significantly increases the sensitivity to radiation therapy. AG14361 enhances the growth-inhibitory and cytotoxic effects of topoisomerase I poisons and increases the persistence of camptothecin-induced DNA single-strand breaks.

Keywords:	1-(4-((dimethylamino)methyl)phenyl)-8,9-dihydro-2,7,9a-triazabenzo[cd]azulen-6(7H)-one,
Supplier:	BPS Bioscience
Supplier-Nr:	27602

Properties

Application:	PARP inhibitor
MW:	320.4 D
Formula:	C19H20N4O

Database Information

CAS :	328543-09-5\| Matching products
KEGG ID :	K10798 \| Matching products

Handling & Safety

Storage:	-20°C (Store aqueous sol. one day max)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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