Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
Close filters
Filter by:
No results were found for the filter!
Item number: Cay11914-1
Smoothened agonist (SAG) is a chlorobenzothiophene-containing compound which acts as a SMO agonist (EC50 = 3 nM) but inhibits hedgehog signaling at high concentrations (>1 µM). It directly binds to SMO and can block SMO inhibition by cyclopamine. Binding of SAG alters the conformation of SMO, leading to its...
Keywords: | Smoothened Agonist,... |
Application: | Smo Agonist |
CAS | 912545-86-9 |
MW: | 490.1 D |
From 34.00€
*
Item number: Cay13258-1
Tamoxifen is an estrogen receptor antagonist (IC50 = 45 nM for the rabbit receptor). It reduces the proliferation of MCF-7 breast cancer cells when used at a concentration of 10 µM. Tamoxifen is active against S. cerevisiae, C. neoformans, and five Candida species (MICs = 12, 64, and 8-64 µg/ml, respectively). It...
Keywords: | 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-ethanamine |
Application: | Estrogen receptor modulator |
CAS | 10540-29-1 |
MW: | 371.5 D |
From 77.00€
*
Item number: Cay10010630-100
Actin disruption is used to study cell functions in vitro (e.g., migration, endocytosis) and in vivo (e.g., tumor cell invasion). Latrunculin A is a bioactive 2-thiazolidinone macrolide derived from sponges that sequesters G-actin and prevents F-actin assembly. It binds monomeric actin with 1:1 stoichiometry and can...
Keywords: | NSC 613011,... |
Application: | Actin polymerization inhibitor |
CAS | 76343-93-6 |
MW: | 421.6 D |
From 66.00€
*
Item number: Cay11932-1
Ionomycin is a calcium ionophore originally isolated from S. conglobatus. It induces intracellular calcium mobilization in X. laevis oocytes when used at a concentration of 5 µM. Ionomycin (5 µM) induces the formation of neutrophil extracellular traps (NETs) in isolated human neutrophils. Ionomycin in combination...
Keywords: | 11,19R,21S-trihydroxy-4R,6S,8S,12R,14R,18R,20S-heptamethyl-22-[octahydro-5'S-[1R-hydroxyethyl]-2S,5'-dimethyl[2,2'R-bifura... |
Application: | Calcium ionophore |
CAS | 56092-82-1 |
MW: | 747.1 D |
From 44.00€
*
Item number: Cay13118-5
Metformin is a biguanide with diverse biological activities. Metformin (250 mg/kg, i.p.) increases hepatic AMPK activity and reduces blood glucose by more than 50% in a liver kinase B1-dependent manner in mice fed normal and high-fat diets, respectively, and reduces blood glucose by 40% in ob/ob mice. It reduces...
Keywords: | 1,1-Dimethylbiguanide hydrochloride, N,N-dimethyl-imidodicarbonimidic diamide, monohydrochloride |
Application: | AMPK activator |
CAS | 1115-70-4 |
MW: | 165.6 D |
From 31.00€
*
Item number: Cay15218-10
FCCP is a potent uncoupler of oxidative phosphorylation in mitochondria that disrupts ATP synthesis by transporting protons across cell membranes. At 40 µM, FCCP induces complete depolymerization of microtubules by increasing intracellular pH via the disruption of the mitochondrial H+ gradient and by decreasing the...
Keywords: | Trifluoromethoxy carbonylcyanide phenylhydrazone, 2-[2-[4-(trifluoromethoxy)phenyl]hydrazinylidene]-propanedinitrile |
Application: | Inhibits mitochondrial oxidative phosphorylation, uncoupling reagent |
CAS | 370-86-5 |
MW: | 254.2 D |
From 88.00€
*
Item number: Cay15588-5
Ganglioside GT1b is a trisialoganglioside that is characterized by having two sialic residues linked to the inner galactose unit. It binds to the neurotoxins botulinum toxin serotype A (BTxA), BTxA heavy chain, and tetanus toxin with IC50 values of 11, 0.74, and 7.2 µM, respectively. Ganglioside GT1b-containing...
Keywords: | Ganglioside G1 Mixture |
Application: | Trisialoganglioside |
MW: | 2126.3 D |
From 145.00€
*
Item number: Cay80310-10
L-NIL is a relatively selective inhibitor of iNOS. It exhibits IC50 values of 0.4-3.3 µM for iNOS as opposed to 8-38 and 17-92 µM for eNOS and nNOS, respectively. L-NIL effectively inhibits iNOS both in vitro and in vivo. L-NIL has been used to demonstrate a critical role for iNOS in the immune response to infection...
Keywords: | N6-(1-iminoethyl)-L-lysine, dihydrochloride |
Application: | iNOS inhibitor |
CAS | 159190-45-1 |
MW: | 260.2 D |
From 54.00€
*
Item number: Cay82120-10
DETA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 20 hours and 56 hours at 37°C and 22-25°C, pH 7.4, respectively, to liberate 2 moles of NO per mole of parent compound.Formal Name:...
Keywords: | Diethylenetriamine NONOate, NOC-18, (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl)amino]diazen-1-ium-1,2-diolate |
Application: | NO donor |
CAS | 146724-94-9 |
MW: | 163.2 D |
From 50.00€
*
Item number: Cay9002863-50
Disuccinimidyl sulfoxide (DSSO) is a protein cross-linking probe designed to be used with mass spectrometry (MS). It contains two symmetric collision-induced dissociation (CID)-cleavable sites that allow effective identification of DSSO-cross-linked peptides based on their distinct fragmentation patterns. The...
Keywords: | DSSO, 3,3'-sulfinylbis-propanoic acid, 1,1'-bis(2,5-dioxo-1-pyrrolidinyl) ester |
Application: | Protein cross-linking probe |
CAS | 1351828-03-9 |
MW: | 388.3 D |
From 54.00€
*
Item number: LKT-N3476.50
Nitisinone is a nitrobenzene inhibitor of HPPD, an enzyme involved in tyrosine degradation. Nitisinone is clinically used to slow the effects of hereditary type 1 tyrosinemia and as a potential treatment for alkaptonuria.
Keywords: | NTBC, orfadin |
Application: | 4-hydroxyphenylpyruvate dioxygenase inhibitor |
CAS | 104206-65-7 |
MW: | 329.23 D |
From 80.00€
*
Item number: Cay11018-10
Cyclic AMP (cAMP) is an important signal carrier necessary for the proper biological response of cells to hormones, neurotransmitters, and other extracellular signals. Forskolin is a naturally occurring diterpene that is produced by the Indian Coleus plant (C. forskohlii). It directly activates adenylyl cyclase...
Keywords: | Coleonol, HL 362, L 75-1362B, NSC 357088, NSC 375489,... |
Application: | Adenylate cyclase activator |
CAS | 66575-29-9 |
MW: | 410.5 D |
From 35.00€
*