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(-)-Altenuene
Item number: Cay21130-1
(-)-Altenuene is a natural mycotoxin that was first isolated from A. tenuis. It has antioxidant activity and inhibits cholinesterases. Unlike tenuazonic acid (Cay-11443), (-)-altenuene does not display toxicity as assessed by the chicken embryo assay. (-)-Altenuene does not display significant topoisomerase...
| Keywords: | 2R,3R,4aR,4a-tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-6H-dibenzo[b,d]pyran-6-one |
| Application: | Mycotoxin, antioxidant, cholinesterase inhibitor |
| CAS | 889101-41-1 |
| MW: | 292.3 D |
1,215.00€
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NADPH, tetrasodium salt
Item number: 16156.1
Nicotinamide adenine dinucleotide phosphate, abbreviated NADP+ or, in older notation, TPN (triphosphopyridine nucleotide), is a coenzyme used in anabolic reactions, such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent. NADPH is the reduced form of NADP+. NADP+ differs from NAD+ in the...
| Keywords: | beta-Nicotinamide-adenine-dinucleotide phosphate, reduced Na4-salt |
| CAS | 2646-71-1 |
| MW: | 833.4 D |
From 91.00€
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Fura Red, AM
Item number: ABD-21048
Ex: 458 nm. Em: 597 nm. Soluble in: DMSO. Fura Red is a visible light-excitable fura-2 analog that offers unique possibilities for ratiometric measurement of calcium ion in single cells by microphotometry, imaging or flow cytometry when used with single excitation, green-fluorescent calcium indicators. Fura Red AM...
| Application: | Cell-permeable ratiometric fluorescent calcium indicator, Fura-2 analog, FC, Single cell imaging |
| CAS | 149732-62-7 |
| MW: | 1089 D |
From 363.00€
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Tentoxin
Item number: Cay11442-1
Tentoxin is a cyclic tetrapeptide first isolated from the plant pathogen A. alternata. It is an herbicide that inhibits chloroplast development, resulting in chlorotic tissue. Tentoxin is selectively phytotoxic, as it kills a number of important weeds at concentrations that have no effects on several important...
| Keywords: | cyclo[N-methyl-L-alanyl-L-leucyl-(alphaZ)-alpha,beta-didehydro-N-methylphenylalanylglycyl] |
| Application: | Herbicide, chloroplast development inhibitor |
| CAS | 28540-82-1 |
| MW: | 414.5 D |
From 287.00€
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Biocytin
Item number: Cay16751-100
Biocytin is a conjugate of biotin and lysine known formally as ?-N-(d-biotinyl)-L-lysine. The addition of lysine to biotin increases the chain length extending from biotin, allowing the synthesis of medium-chain reagents. It also provides terminal carboxyl and amino groups for derivatization or conjugation to...
| Keywords: | e-N-(d-Biotinyl)-L-lysine, N6-[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]-L-lysine |
| Application: | Neuroanatomical tracer |
| CAS | 576-19-2 |
| MW: | 372.5 D |
From 56.00€
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Phorbol 12-myristate 13-acetate
Item number: AG-CN2-0010-M001
Most commonly-used phorbol ester, Binds to and activates protein kinase C (PKC) at nM concentrations, Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors...
| Keywords: | PMA, TPA, 12-O-Tetradecanoylphorbol 13-acetate |
| Application: | PKC activator |
| CAS | 16561-29-8 |
| MW: | 616,8 D |
From 44.00€
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L-Buthionine-(S,R)-Sulfoximine
Item number: Cay14484-250
L-Buthionine-(S,R)-sulfoximine is an irreversible inhibitor of gamma-glutamylcysteine synthetase (Ki = 25 µM). It inhibits the proliferation of ZAZ and M14 melanoma cells, as well as A2780 ovarian and MCF-7 breast cancer cells (IC50s = 4.9, 18, 8.5, and 26.5 µM, respectively). L-Buthionine-(S,R)-sulfoximine (100µM)...
| Keywords: | BSO, NSC 326231, 2S-amino-4-(S-butylsulfonimidoyl)-butanoic acid |
| Application: | Oxidative stress inducer |
| CAS | 83730-53-4 |
| MW: | 222.3 D |
From 127.00€
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Cisplatin
Item number: Cay13119-50
Cisplatin is a platinum-containing compound that acts as a DNA-crosslinking agent and interferes with replication and transcription, culminating in apoptosis. It forms intra- and interstrand crosslinks with DNA with intrastrand guanine-to-guanine or guanine-to-alanine links accounting for the majority of DNA...
| Keywords: | cis-Diamminedichloroplatinum, CDDP, Cisplatinum, NSC 119875, (SP-4-2)-diamminedichloro-platinum |
| Application: | Alkylating agent, apoptosis inducer |
| CAS | 15663-27-1 |
| MW: | 300.1 D |
From 71.00€
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nor-NOHA (acetate)
Item number: Cay10006861-10
L-Arginine serves as a common substrate for both nitric oxide synthase (NOS) and arginase in the cell. NOS catalyzes the oxidation of arginine to citrulline and NO with Nomega-hydroxy-L-arginine (NOHA) formed as an intermediate. Arginase, on the other hand, catalyzes the hydrolysis of arginine into urea and...
| Keywords: | Nomega-hydroxy-nor-Arginine, 2S-amino-4-[[(hydroxyamino)iminomethyl]amino]-butanoic acid, diacetate |
| Application: | Arginase inhibitor |
| CAS | 1140844-63-8 |
| MW: | 296.3 D |
From 34.00€
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1-NA-PP1
Item number: Cay10954-10
1-NA-PP1 is a reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase. 1-NA-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over...
| Keywords: | 1-Naphthyl-PP1, PP1 Analog, 1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| CAS | 221243-82-9 |
| MW: | 317.4 D |
From 36.00€
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BAY 60-7550
Item number: Cay10011135-1
The second messengers cAMP and cGMP are important mediators of signal transduction and hence a wide range of cellular processes including vasodilation and synaptic plasticity. Type 2 cyclic nucleotide phosphodiesterases (PDE2) isoforms inactivate cAMP and cGMP by hydrolyzing the phosphodiester bond. BAY 60-7550 is a...
| Keywords: | 2-[(3,4-dimethoxyphenyl)methyl]-7-[(1R)-1-hydroxyethyl]-4-phenylbutyl]-5-methyl-imidazo[5,1-f][1,2,4]triazin-4(1H)-one |
| Application: | PDE2 inhibitor |
| CAS | 439083-90-6 |
| MW: | 476.6 D |
From 139.00€
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2-Hydroxypropyl-beta-cyclodextrin
Item number: Cay16169-25
2-Hydroxypropyl-beta-cyclodextrin (HP-beta-CD) is a cyclic oligosaccharide containing seven D-(+)-glucopyranose units that is widely used to improve the aqueous solubility of various compounds, especially those containing a phenyl group. The circular arrangement of its glucose units produces a torus-shaped ring...
| Keywords: | HP-beta-CD, 2-hydroxypropyl ethers beta-cyclodextrin |
| Application: | Solubility enhancer |
| CAS | 128446-35-5 |
| MW: | 1541.6 D |
From 58.00€
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