360A (iodide)
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Larger quantity required? Request bulk
360A is an inhibitor of telomerase (IC50 = 0. µM). It decreases the viability of in T98G glioma... more
Product information "360A (iodide)"
360A is an inhibitor of telomerase (IC50 = 0. µM). It decreases the viability of in T98G glioma fibroblasts, CB193 astrocytoma and U-118 MG glioma cells, and primary human astrocytes (IC50s = 4. 3. 8. and 17. µM, respectively). 360A (5 µM) induces sister chromatid fusions and telomere loss in HeLa cervical cancer cells. It induces cell cycle arrest at the S phase and increases gamma histone H2AX (gammaH2AX) foci, a marker of DNA damage, in GM03657 B cell lymphocytes.. Solulibility: DMSO: Slightly Soluble: 0.1-1 mg/ml: .
| Keywords: | 3,3'-[2,6-pyridinediylbis(carbonylimino)]bis[1-methyl-quinolinium, diiodide |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 42501 |
Properties
| Application: | Telomerase inhibitor |
| MW: | 703.3 D |
| Formula: | C27H23N5O2 . 2I |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 737763-37-0| Matching products |
| KEGG ID : | K11126 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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