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360A (iodide)
Item number: Cay42501-10
360A is an inhibitor of telomerase (IC50 = 0. µM). It decreases the viability of in T98G glioma fibroblasts, CB193 astrocytoma and U-118 MG glioma cells, and primary human astrocytes (IC50s = 4. 3. 8. and 17. µM, respectively). 360A (5 µM) induces sister chromatid fusions and telomere loss in HeLa cervical cancer...
| Keywords: | 3,3'-[2,6-pyridinediylbis(carbonylimino)]bis[1-methyl-quinolinium, diiodide |
| Application: | Telomerase inhibitor |
| CAS | 737763-37-0 |
| MW: | 703.3 D |
From 259.00€
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360A iodide
Item number: TGM-T13504-100mg
Description: 360A iodide is a selective G-quadruplex stabilizer that inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay). Target: Telomerase. Smiles: [I-].[I-].C[n+]1cc(NC(=O)c2cccc(n2)C(=O)Nc2c[n+](C)c3ccccc3c2)cc2ccccc12. References: Pennarun G, et al. Apoptosis related to telomere instability and cell...
| Keywords: | 360 A iodide |
| CAS | 737763-37-0 |
| MW: | 703.31 D |
From 745.00€
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