Sancycline (hydrochloride)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay28118-50 50 mg -

6 - 10 business days*

47.00€
Cay28118-100 100 mg -

6 - 10 business days*

90.00€
Cay28118-250 250 mg -

6 - 10 business days*

212.00€
Cay28118-500 500 mg -

6 - 10 business days*

375.00€
 
Sancycline is a semisynthetic tetracycline antibiotic that is more active than tetracycline... more
Product information "Sancycline (hydrochloride)"
Sancycline is a semisynthetic tetracycline antibiotic that is more active than tetracycline (Cay-14328) against 339 strains of anaerobic bacteria (average MIC90s = 1 and 32 µg/ml, respectively). Sancycline is active against tetracycline-resistant E. coli, S. aureus, and E. faecalis strains with MICs ranging from 0.06 to 1 µg/ml. In vivo, sancycline is active against S. aureus in mice with ED50 values of 0.46 and 0.6 mg/kg for intravenous and subcutaneous administration, respectively.Formal Name: (4S,4aS,5aR,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide, monohydrochloride. CAS Number: 6625-20-3. Synonyms: 6-Demethyl-6-deoxytetracycline, NSC 51812. Molecular Formula: C21H22N2O7 . HCl. Formula Weight: 450.9. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20mg/mL, DMSO: 20mg/mL, DMSO:PBS (pH 7.2) (1:5): 0.15 mg/mL, Ethanol: 5mg/mL. lambdamax: 221, 268, 350 nm. SMILES: O=C1C(C(N)=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@](C3=C(O)[C@@]21O)([H])CC4=CC=CC(O)=C4C3=O.Cl. InChi Code: InChI=1S/C21H22N2O7.ClH/c1-23(2)15-10-7-9-6-8-4-3-5-11(24)12(8)16(25)13(9)18(27)21(10,30)19(28)14(17(15)26)20(22)29,/h3-5,9-10,15,24,26-27,30H,6-7H2,1-2H3,(H2,22,29),1H/t9-,10-,15-,21-,/m0./s1. InChi Key: NHHHLWBNBLFCSB-QKYUADJBSA-N.
Keywords: 6-Demethyl-6-deoxytetracycline, NSC 51812, (4S,4aS,5aR,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide, monohydrochloride
Supplier: Cayman Chemical
Supplier-Nr: 28118

Properties

Application: Antibacterial tetracycline antibiotic
MW: 450.9 D
Formula: C21H22N2O7 . HCl
Purity: >95%
Format: Crystalline Solid

Database Information

CAS : 6625-20-3| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H302, H361
P Phrases: P201, P202, P264, P270, P280, P330, P301+P310, P308+P313, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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