Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used... read more »
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Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

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Bekanamycin
Bekanamycin

Item number: Cay34561-1

Bekanamycin is an aminoglycoside antibiotic. It is active against S. aureus, E. coli, P. aeruginosa, and P. rettgeri (MICs = 0.78-25 µg/ml). Bekanamycin binds to the ribosomal decoding A site to interfere with bacterial protein synthesis.Formal Name:...
Keywords: Kanamycin B, Kanendomycin, Nebramycin V,...
Application: Aminoglycoside antibiotic, Antibacterial, Protein biosynthesis inhibitor
CAS 4696-76-8
MW: 483.5 D
From 65.00€ *
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25-Desacetyl Rifampicin
25-Desacetyl Rifampicin

Item number: Cay34817-1

25-Desacetyl rifampicin is a major active metabolite of the rifamycin antibiotic rifampicin (Cay-14423). 25-Desacetyl rifampicin is active against M. smegmatis (MIC99 = 2.66 µM).Formal Name: 25-O-deacetyl-3-[(E)-[(4-methyl-1-piperazinyl)imino]methyl]-rifamycin. CAS Number: 16783-99-6. Synonyms: Desacetylrifampicin....
Keywords: Desacetylrifampicin, 25-O-deacetyl-3-[(E)-[(4-methyl-1-piperazinyl)imino]methyl]-rifamycin
Application: Rifampicin major active metabolite
CAS 16783-99-6
MW: 780.9 D
257.00€ *
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Tunicamycin
Tunicamycin

Item number: Cay11445-5

Tunicamycin mixture is a mixture of tunicamycins with variable trans-2,3-unsaturated branched chain fatty acid (BFCA) chain lengths. Tunicamycins are anti-microbial agents that are active against Gram-positive bacteria, fungi, and viruses. They inhibit the N-acetylhexosamine (HexNAc) phosphotransferase family of...
Application: N-glycosylation inhibitor
CAS 11089-65-9
MW: 845 D
From 34.00€ *
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Actinomycin D
Actinomycin D

Item number: Cay11421-10

Actinomycin D is a cyclic polypeptide-containing antibiotic that binds to DNA and blocks transcription. It binds to pre-melted double-stranded DNA in transcription bubbles and once bound is slow to dissociate. DNA in transcriptionally hyperactive cancer cells efficiently and rapidly bind actinomycin D at low...
Keywords: Cosmegen, Dactinomycin, Meractinomycin, NCI C04682, NSC 3053, Oncostatin K,...
Application: Cancer studies, Antineoplastic
CAS 50-76-0
MW: 1255.5 D
From 69.00€ *
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Oligomycin A
Oligomycin A

Item number: Cay11342-5

Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms. Different oligomycin isomers are highly specific for the disruption of mitochondrial metabolism. Oligomycin A, a dominant analog of the isomers, is an inhibitor of mitochondrial F1FO ATP synthase that induces apoptosis...
Keywords: MCH 32,...
Application: Apoptosis inducer
CAS 579-13-5
MW: 791.1 D
From 59.00€ *
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Desfuroylceftiofur
Desfuroylceftiofur

Item number: Cay20360-1

Desfuroylceftiofur is an active metabolite of the broad-spectrum cephalosporin antibiotic ceftiofur (Cay-27301). It is formed from ceftiofur by bovine kidney and liver esterases. Desfuroylceftiofur is active against 539 veterinary isolates of Gram-negative bacteria and Gram-positive cocci bacteria (MIC50s = 0.0078-1...
Keywords: (6R,7R)-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-(mercaptomethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oc...
Application: Ceftiofur metabolite
CAS 120882-22-6
MW: 429.5 D
From 170.00€ *
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Tilmicosin-d3
Tilmicosin-d3

Item number: Cay33545-5

Tilmicosin-d3 is intended for use as an internal standard for the quantification of tilmicosin (Cay-18190) by GC- or LC-MS. Tilmicosin is a macrolide antibiotic. It is active against macrolide-susceptible strains of M. haemolytica, P. multocida, and E. coli (MICs = 4, 4, and 128 µM, respectively), as well as a...
Keywords: (4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-(((2R,3R,4S,5S,6R)-3,5-dihydroxy-6-methyl-4-(methyl(methyl-d3)amino)tetrahydro-2H-pyran...
Application: GC-MS, LC-MS internal standard, Quantification, Macrolide antibiotic
MW: 872.2 D
283.00€ *
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Maduramicin (ammonium salt)
Maduramicin (ammonium salt)

Item number: Cay34270-100

Maduramicin is a polyether ionophore antibiotic that has been found in Nocardia. It selectively binds to potassium, rubidium, sodium, lithium, and cesium ions over divalent cations. Maduramicin is active against Gram-positive bacteria (MICs = 0.9-125 µg/ml) but not Gram-negative bacteria (MICs = >1,000 µg/ml) or...
Keywords: Antibiotic X-14868A, CL 259,971, Maduramycin, Prinicin, maduramicin alpha, monoammonium salt
Application: Polyether ionophore antibiotic, Coccidiostat
CAS 84878-61-5
MW: 934.2 D
From 60.00€ *
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Faropenem (sodium salt hydrate)
Faropenem (sodium salt hydrate)

Item number: Cay34507-10

Faropenem is a broad-spectrum penem antibiotic. It is active against a panel of 12 Gram-positive (MIC50s = 0.008-1 mg/L) and 15 Gram-negative (MIC50s = 0.06-16 mg/L) bacteria. Faropenem (20 mg/kg) reduces the number of lung colony forming units (CFUs) in a mouse model of H. influenzae-induced respiratory tract...
Keywords: (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furanyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic...
Application: Penem antibiotic, Antibacterial, Cell wall biosynthesis inhibitor
CAS 158365-51-6
MW: 352.3 D
From 87.00€ *
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Puromycin (hydrochloride)
Puromycin (hydrochloride)

Item number: Cay13884-100

Puromycin is an aminonucleoside antibiotic, derived from S. alboniger, that blocks protein synthesis in both prokaryotes and eukaryotes by causing premature termination of nascent polypeptide chains. A portion of the puromycin molecule resembles the 3' end of aminoacylated tRNA. It enters the A site of the ribosome...
Keywords: CL 13,900, CL 16,536, NSC 3055, PDH, 3'-[[2S-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-adenosine,...
Application: Aminonucleosid antibiotic
CAS 58-58-2
MW: 544.4 D
From 39.00€ *
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Spiramycin
Spiramycin

Item number: LKT-S6232.5

A macrolide antibiotic. It has been shown to decrease the replication index of humanlymphocytes.
Keywords: SPM, RP-5337
Application: Antibiotic, macrolide
CAS 8025-81-8
MW: 842,05 D
From 112.00€ *
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N-Demethylvancomycin (hydrochloride)
N-Demethylvancomycin (hydrochloride)

Item number: Cay34119-10

N-Demethylvancomycin is a glycopeptide antibiotic that has been found in Nocardia orientalis. It is active against several strains of S. aureus and S. epidermidis in vitro and in vivo. Formulations containing N-demethylvancomycin have been used in the treatment of bacterial infections.Formal Name:...
Keywords: A51568A, Norvancomycin, 56-demethyl-vancomycin, hydrochloride
Application: Glycopeptide antibiotic
CAS 198774-23-1
MW: 1435.2 D
From 65.00€ *
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