Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used... read more »
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Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

48 from 67 pages
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Geldanamycin
Geldanamycin

Item number: LKT-G1646.1

A benzoquinoid ansamycin antibiotic having antitumor activities. It suppresses DNA replication by inhibiting c-myc gene expression in lymphoblastoma L5178Y cells. It inhibits tyrosine kinases and induces increased p53 protein involved in cell-cycle arrests of human ovarian tumor cells. It inhibits the 90 kDa heat...
Application: Antibiotic
CAS 30562-34-6
MW: 560,64 D
269.00€ *
Review
Polymyxin B sulfate
Polymyxin B sulfate

Item number: LKT-P5747.1

Mixture of polymyxin B1, B2, B3 and B1-1 sulfates
Application: Antibacterial agent
CAS 1405-20-5
From 100.00€ *
Review
Sulbactam
Sulbactam

Item number: LKT-S8244.1

A beta-lactamase inhibitor that has similar characteristics as ampicillin. Often used in combination with other antibiotics.
Application: Antibiotic, Beta-lactamase inhibitor
CAS 68373-14-8
MW: 233,24 D
From 141.00€ *
Review
Virginiamycin M1
Virginiamycin M1

Item number: LKT-V3325.1

Macrolide antibiotic, peptidyl transferase inhibitor, protein translation inhibitor.
Keywords: Mikamycin A, Staphilomycin, Ostreogrycin A, Virginiamycin M1, Pristinamycin IIA
Application: Macrolide antibiotic, peptidyl transferase inhibitor, protein translation inhibitor
CAS 21411-53-0
MW: 525.59 D
From 59.00€ *
Review
Ristocetin A Sulfate (Ristocetin, Ristomycin III, Spontin, Riston)
Ristocetin A Sulfate (Ristocetin, Ristomycin III,...

Item number: R2032-22.10

Ristocetin A is a potent antibacterial glycopeptide antibiotic but was withdrawn for clinical use following a high incidence of thrombocytopenia. Further investigation found that ristocetin A induced platelet aggregation by binding to a factor absent in people suffering from von Willebrand's disease and lead to the...
Application: Platelet aggregation inducer
CAS 11140-99-1
From 576.00€ *
Review
Viridicatumtoxin
Viridicatumtoxin

Item number: AG-CN2-0172-M001

Isolated from Penicillium brasilianum. Soluble in ethanol, methanol or DMSO (all 1mg/ml). Potent antibacterial agent with activity against several strains of Staphylococcus aureus, including Methicillin-resistant S. aureus (MRSA) and quinolone-resistant S. aureus (QRSA). Inhibits bacterial undecaprenyl pyrophosphate...
Keywords: NSC 159628, BRN 2934660, Viridicatumtoxin A
Application: Tetracycline antibiotic, UPP inhibitor
CAS 39277-41-3
MW: 565.6 D
198.00€ *
Review
Actagardin
Actagardin

Item number: AG-CN2-0300-M001

Isolated from Actinoplanes sp. Beige powder. Soluble in ethanol, DMSO or aqueous acetonitrile. Tetracyclic class II lantibiotic. Structurally related to mersacidine. Antibiotic. Antibacterial against Gram-positive bacteria and Gram-negative microorganisms. Specifically inhibits peptidoglycan synthesis in the cell...
Keywords: Gardimycin, Antibiotic A 3802-IV-3
Application: Antibiotic
CAS 59165-34-3
MW: 1890.2 D
From 105.00€ *
Review
BE-31405
BE-31405

Item number: AG-CN2-0302-M001

Isolated from Penicillum minioluyeum. White to off-white powder. Soluble in DMSO. Broad spectrum antifungal agent compared to sordarin. Shows growth inhibitory activity against pathogenic fungal strains such as Candida albicans, Candida glabrata and Cryptococcus neoformans. Inhibits the protein synthesis in Candida...
Application: Antifungal
CAS 158054-02-5
MW: 532.6 D
319.00€ *
Review
NAI-108
NAI-108

Item number: AG-CN2-0308-C500

Isolated from Actinoallomurus sp. White to off-white powder. Soluble in DMSO, aqueous acetonitrile or ethanol. Antibacterial class I lantibiotic. Brominated variant of NAI-107. Inhibits cell wall synthesis and consequently bacterial growth by forming a complex with lipid intermediate II (Lipid II), a key...
Keywords: Lantibiotic NAI 108 A1/A2 Mixture
Application: Antibiotic, Cell wall synthesis inhibitor
CAS 1820892-86-1
297.00€ *
Review
NAI-857
NAI-857

Item number: AG-CN2-0311-M001

Isolated from Strepomyces sp. Beige powder. Soluble in DMSO or water. Antibacterial class I lantibiotic. Inhibits cell wall synthesis and consequently bacterial growth by forming a complex with lipid intermediate II (Lipid II), a key intermediate in peptidoglycan biosynthesis. Interfers with late stages of cell wall...
Keywords: Lantibiotic NAI 857
Application: Antibacterial, Cell wall synthesis inhibitor
CAS 1648732-25-5
MW: 2170.4 D
From 94.00€ *
Review
GE2270 D2
GE2270 D2

Item number: AG-CN2-0304-M001

Isolated from Planobispora rosea. White to off-white powder. Soluble in DMSO or other organic solvents. Thiopeptide antibiotic. Antibacterial agent by inhibiting bacterial protein synthesis. Active against numerous Gram-positive pathogens, including methicillin-resistant strains of Staphylococcus aureus and...
Keywords: Antibiotic GE 2270A, MDL 62879
Application: Thiopeptide antibiotic, EF-Tu inhibitor
CAS 138948-60-4
MW: 1276.5 D
From 105.00€ *
Review
GE23077 A1/B1
GE23077 A1/B1

Item number: AG-CN2-0305-M001

Isolated from Actinomadura sp. White to off-white powder. Soluble in DMSO or water. Cyclic heptapeptide antibiotic. Potent and selective inhibitor of bacterial RNA polymerase (RNAP). Inhibits Gram-positive (Bacillus subtilis) and Gram-negative (Escherichia coli) RNAPs with IC50 ~20nM, whereas it is not active on E....
Keywords: Antibiotic GE23077A1/Antibiotic GE23077B1 Mixture
Application: Antibiotic
CAS 752989-46-1
MW: 805.8 D
From 105.00€ *
Review
48 from 67 pages