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Product information "WM3734 Non-Viable Cell Pellet"
Cells were grown sub-confluent to approximately (2x10^6) cells in Tumor specialized media and then trypsinized. Cells were harvested and cell pellets were flash frozen and stored at -80°C. Non-viable cell pellet was generated from cell line WM3734. WM3734 is a tumorigenic metastatic primary melanoma cell line. This cell line was established from a brain metastatic site in a 24-year-old female. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. WM3734 cells produce xenograft tumors when injected into immunocompromised mice.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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