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Item number: ARG83724.1
Protein function: Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6,...
| Keywords: | Za11, Za11, IL-21, IL-21, Interleukin-21, Interleukin-21 |
| Application: | ELISA |
| Species reactivity: | mouse |
719.00€
*
Item number: ARG83732.1
Protein function: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and...
| Keywords: | CDF, CDF, IL-6, IL-6, IFNB2, BSF-2, BSF-2, IFN-beta-2, IFN-beta-2, Interferon beta-2, Interferon beta-2, Hybridoma growth... |
| Application: | ELISA |
| Species reactivity: | rat |
719.00€
*
Item number: ARG83648.96
Protein function: Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis. {ECO:0000269, PubMed:11985878, ECO:0000269, PubMed:1517212, ECO:0000269, PubMed:1748670, ECO:0000269, PubMed:2714437}. [The UniProt...
| Keywords: | ACHE, AChE, AChE, Acetylcholinesterase, Acetylcholinesterase |
| Application: | ELISA |
| Species reactivity: | human |
1,052.00€
*
Item number: ARG83651.96
Protein function: Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity. {ECO:0000269, PubMed:11165938, ECO:0000269, PubMed:11292659, ECO:0000269, PubMed:16512877}. [The...
| Keywords: | ECM1, Secretory component p85, Secretory component p85, Extracellular matrix protein 1, Extracellular matrix protein 1 |
| Application: | ELISA |
| Species reactivity: | human |
1,052.00€
*
Item number: ARG83659.96
Protein function: Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria (PubMed:9468508). Also plays a role in binding of unopsonized particles by alveolar macrophages. Binds to the secretoglobin SCGB3A2 (PubMed:12847263). [The UniProt Consortium]
| Keywords: | MARCO, SCARA2, Macrophage receptor MARCO, Macrophage receptor MARCO, Scavenger receptor class A member 2, Scavenger... |
| Application: | ELISA |
| Species reactivity: | mouse |
1,052.00€
*
Item number: ARG83663.96
Protein function: Involved in transforming growth factor beta (TGF-beta)- induced smooth muscle differentiation. TGF-beta induces expression and translocation of OLFM2 to the nucleus where it binds to SRF, causing its dissociation from the transcriptional repressor HEY2/HERP1 and facilitating binding of SRF to...
| Keywords: | NOE2, OLFM2, Noelin-2, Noelin-2, Olfactomedin-2, Olfactomedin-2 |
| Application: | ELISA |
| Species reactivity: | human |
1,052.00€
*
Item number: ARG83665.96
Protein function: May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity. Component of the elastin-associated microfibrils (PubMed:8557636). {ECO:0000250, UniProtKB:Q9QZJ6, ECO:0000269, PubMed:8557636}. [The...
| Keywords: | MP25, MP25, MFAP5, MAGP2, MFAP-5, MAGP-2, MFAP-5, MAGP-2, Microfibrillar-associated protein 5, Microfibrillar-associated... |
| Application: | ELISA |
| Species reactivity: | human |
1,052.00€
*
Item number: ARG83666.96
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination (PubMed:15350543). Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of...
| Keywords: | NOTCH3, Notch 3, Notch 3 intracellular domain, Notch 3 extracellular truncation, Neurogenic locus notch homolog protein 3 |
| Application: | ELISA |
| Species reactivity: | human |
1,052.00€
*
Item number: ARG83667.96
Protein function: May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses. [The UniProt Consortium]
| Keywords: | NPTXR, Neuronal pentraxin receptor, Neuronal pentraxin receptor |
| Application: | ELISA |
| Species reactivity: | human |
1,052.00€
*
Item number: ARG83675.1
Protein function: Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway (PubMed:17671174). Involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that would result from...
| Keywords: | IDO, IDO1, IDO-1, IDO-1, Indoleamine 2,3-dioxygenase 1, Indoleamine 2,3-dioxygenase 1, Indoleamine-pyrrole... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83677.1
Protein function: Associates with IFNGR2 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:7615558, PubMed:2971451, PubMed:7617032, PubMed:10986460). Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:7673114). Plays an essential role in the IFN-gamma pathway that is...
| Keywords: | CD119, CD119, CDw119, CDw119, IFN-gamma-R1, IFN-gamma-R1, IFN-gamma receptor 1, IFN-gamma receptor 1, IFN-gamma-R-alpha... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*
Item number: ARG83678.1
Protein function: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. [The UniProt Consortium]
| Keywords: | IL3, IL-3, MCGF, IL-3, MCGF, Interleukin-3, Interleukin-3, Mast cell growth factor, Mast cell growth factor,... |
| Application: | ELISA |
| Species reactivity: | human |
719.00€
*