arigoQIK(R) Human IDO1 / INDO ELISA Development Kit

arigoQIK(R) Human IDO1 / INDO ELISA Development Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG83675.1 1 kit (15 plates) - -

10 - 15 business days*

719.00€
 
Protein function: Catalyzes the first and rate limiting step of the catabolism of the essential... more
Product information "arigoQIK(R) Human IDO1 / INDO ELISA Development Kit"
Protein function: Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway (PubMed:17671174). Involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that would result from uncontrolled and overreacting immune responses (PubMed:25691885). Tryptophan shortage inhibits T lymphocytes division and accumulation of tryptophan catabolites induces T-cell apoptosis and differentiation of regulatory T-cells (PubMed:25691885). Acts as a suppressor of anti-tumor immunity (PubMed:23103127, PubMed:25157255, PubMed:14502282, PubMed:25691885). Limits the growth of intracellular pathogens by depriving tryptophan (PubMed:25691885). Protects the fetus from maternal immune rejection (PubMed:25691885). {ECO:0000269, PubMed:14502282, ECO:0000269, PubMed:17671174, ECO:0000303, PubMed:23103127, ECO:0000303, PubMed:25157255, ECO:0000303, PubMed:25691885}. [The UniProt Consortium]
Keywords: IDO, IDO1, IDO-1, IDO-1, Indoleamine 2,3-dioxygenase 1, Indoleamine 2,3-dioxygenase 1, Indoleamine-pyrrole 2,3-dioxygenase, Indoleamine-pyrrole 2,3-dioxygenase
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG83675

Properties

Application: ELISA
Species reactivity: human
Format: Solid Phase

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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