Human OLFM2 ELISA Kit

Human OLFM2 ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG83663.96 96 wells - -

10 - 15 business days*

1,052.00€
 
Protein function: Involved in transforming growth factor beta (TGF-beta)- induced smooth muscle... more
Product information "Human OLFM2 ELISA Kit"
Protein function: Involved in transforming growth factor beta (TGF-beta)- induced smooth muscle differentiation. TGF-beta induces expression and translocation of OLFM2 to the nucleus where it binds to SRF, causing its dissociation from the transcriptional repressor HEY2/HERP1 and facilitating binding of SRF to target genes (PubMed:25298399). Plays a role in AMPAR complex organization. Is a regulator of vascular smooth-muscle cell (SMC) phenotypic switching, that acts by promoting RUNX2 and inhibiting MYOCD binding to SRF. SMC phenotypic switching is the process through which vascular SMCs undergo transition between a quiescent contractile phenotype and a proliferative synthetic phenotype in response to pathological stimuli. SMC phenotypic plasticity is essential for vascular development and remodeling. [The UniProt Consortium]
Keywords: NOE2, OLFM2, Noelin-2, Noelin-2, Olfactomedin-2, Olfactomedin-2
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG83663

Properties

Application: ELISA
Species reactivity: human
Format: Solid Phase

Database Information

UniProt ID : O95897 | Matching products
Gene ID : GeneID 93145 | Matching products

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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