Products from Indigo Biosciences
Indigo Biosciences, Inc. was founded in 2005 in State College, Pennsylvania by Dr. Jack Vanden Heuvel and Dr. Blake Peterson. It remains a privately held biosciences company offering products and services focused on in vitro toxicology and nuclear receptors. These receptors comprise a major class of therapeutic drug targets. The company’s founders leveraged their collective expertise in nuclear receptor biology, toxicology, medical chemistry and molecular biology to establish the core platform technology of the company.
More information at: www.indigobiosciences.com
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PPARdelta (mouse) Reporter Assay Kit
Item number: IB-M00121
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the mouse peroxisome proliferator-activated receptor delta (NR1C2), a ligand-dependent transcription factor commonly referred to as PPARD or PPARdelta. INDIGO's reporter cells include...
| Keywords: | NUC1, Nr1c2, Ppard, PPAR-beta, PPAR-delta, Nuclear hormone receptor 1, Nuclear receptor subfamily 1 group C member 2,... |
| Application: | Functional activity screening |
| Species reactivity: | mouse |
From 1,448.00€
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CAR (Mouse) Reporter Assay System
Item number: IB-M00901
Protein function: Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element. [The...
| Keywords: | Car, CAR, Nr1i3, Orphan nuclear receptor MB67, Constitutive androstane receptor, Nuclear receptor subfamily 1 group I... |
| Application: | Functional activity screening |
| Species reactivity: | mouse |
From 1,448.00€
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PXR (Cynomolgus Monkey) Reporter Assay System
Item number: IB-C07001
| Keywords: | Nr1i2, Nuclear receptor subfamily 1 group I member 2 |
| Application: | Functional activity screening |
| Species reactivity: | Cynomolgus monkey |
From 1,448.00€
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PXR (Dog) Reporter Assay System
Item number: IB-D07001
| Keywords: | Nr1i2, Nuclear receptor subfamily 1 group I member 2 |
| Application: | Functional activity screening |
| Species reactivity: | dog |
From 1,448.00€
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LXRbeta (human) Reporter Assay Kit
Item number: IB-IB00301
This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of human liver X receptor beta (NR1H2), a ligand-dependent transcription factor commonly referred to as LXRbeta. INDIGO's reporter cells include the luciferase reporter gene...
| Keywords: | LXRB, NR1H2, Nuclear receptor NER, Liver X receptor beta, Oxysterols receptor LXR-beta, Ubiquitously-expressed nuclear... |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,448.00€
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VDR (human) Reporter Assay Kit
Item number: IB-IB00701
This nuclear receptor assay system utilizes proprietary human cells engineered to provide constitutive, high-level expression of the human vitamin D receptor (NR1I1), a ligand-dependent transcription factor commonly referred to as VDR. INDIGO's reporter cells include the luciferase reporter gene functionally linked...
| Keywords: | VDR, NR1I1, Vitamin D3 receptor, 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1 |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,448.00€
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TRalpha (human) Reporter Assay Kit
Item number: IB-IB01001
This nuclear receptor assay system utilizes proprietary human cells engineered to provide constitutive, high-level expression of the human thyroid hormone receptor alpha (NR1A1), a ligand-dependent transcription factor commonly referred to as TRalpha. INDIGO's reporter cells include the luciferase reporter gene...
| Keywords: | THRA, EAR7, EAR-7, c-erbA-1, c-erbA-alpha, V-erbA-related protein 7, Thyroid hormone receptor alpha, Nuclear receptor... |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,448.00€
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PPARalpha (rat) Reporter Assay Kit
Item number: IB-R00111
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the rat peroxisome proliferator-activated receptor alpha (NR1C1), a ligand-dependent transcription factor commonly referred to as PPARA or rPPARalpha. INDIGO's reporter cells include...
| Keywords: | PPARA, NR1C1, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1, Peroxisome proliferator-activated receptor alpha |
| Application: | Functional activity screening |
| Species reactivity: | rat |
From 1,448.00€
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TRbeta (human) Reporter Assay Kit
Item number: IB-IB01101
This nuclear receptor assay system utilizes proprietary human cells engineered to provide constitutive, high-level expression of the human thyroid hormone receptor beta (NR1A2), a ligand-dependent transcription factor commonly referred to as TRbeta. INDIGO's reporter cells include the luciferase reporter gene...
| Keywords: | THRB, ERBA2, c-erbA-2, c-erbA-beta, Thyroid hormone receptor beta, Nuclear receptor subfamily 1 group A member 2 |
| Application: | Functional activity screening |
| Species reactivity: | human |
From 1,448.00€
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PPARalpha (mouse) Reporter Assay Kit
Item number: IB-M00111
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the mouse peroxisome proliferator-activated receptor alpha (NR1C1), a ligand-dependent transcription factor commonly referred to as PPARA or mPPARalpha. INDIGO's reporter cells include...
| Keywords: | Ppara, Nr1c1, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1, Peroxisome proliferator-activated receptor alpha |
| Application: | Functional activity screening |
| Species reactivity: | mouse |
From 1,448.00€
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PPARdelta (rat) Reporter Assay Kit
Item number: IB-R00121
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the rat peroxisome proliferator-activated receptor delta (NR1C2), a ligand-dependent transcription factor commonly referred to as PPARD or rPPARdelta. INDIGO's reporter cells include...
| Keywords: | Ppard, PPARb, Protein Ppard, Peroxisome proliferator-activated receptor beta, Peroxisome proliferator activated receptor... |
| Application: | Functional activity screening |
| Species reactivity: | rat |
From 1,448.00€
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PXR (Rat) Reporter Assay System
Item number: IB-R07001
Protein function: Nuclear receptor that binds and is activated by a variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, endogenous compounds and drugs. Response to specific...
| Keywords: | Pxr, Nr1i2, Pregnane X receptor, Orphan nuclear receptor PXR, Nuclear receptor subfamily 1 group I member 2 |
| Application: | Functional activity screening |
| Species reactivity: | rat |
From 1,448.00€
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