Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Human FXYD4-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120686.10
This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport...
| Keywords: | FXYD4, FXYD domain-containing ion transport regulator 4 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 9.4 kD |
From 1,185.00€
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Human ASIC4-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120688.10
This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a...
| Keywords: | ACCN4, ASIC4, Acid-sensing ion channel 4, Amiloride-sensitive cation channel 4, Amiloride-sensitive cation channel 4,... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 70.1 kD |
From 1,185.00€
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Human CA2D3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120689.10
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio....
| Keywords: | CACNA2D3 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 123 kD |
From 1,185.00€
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Human CXG2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120690.10
This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene...
| Keywords: | Cx47, GJC2, GJA12, Cx46.6, Connexin-47, Connexin-46.6, Gap junction gamma-2 protein, Gap junction alpha-12 protein |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 47 kD |
From 1,185.00€
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Human KCD15-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120696.10
During embryonic development, interferes with neural crest formation (By similarity). Inhibits AP2 transcriptional activity by interaction with its activation domain.[UniProtKB/Swiss-Prot Function]. Human KCD15-Strep full length protein-synthetic nanodisc. Protein function: During embryonic development, interferes...
| Keywords: | KCTD15, BTB/POZ domain-containing protein KCTD15, Potassium channel tetramerization domain-containing protein 15 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 31.9 kD |
From 1,185.00€
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Human BACD3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120703.10
The protein encoded by this gene binds proliferating cell nuclear antigen (PCNA) and may be involved in DNA synthesis and cell proliferation. In addition, the encoded protein may be a tumor suppressor. Several protein-coding and non-protein coding transcript variants have been found for this gene. [provided by...
| Keywords: | KCTD10, ULR061, MSTP028, hBACURD3, BTB/POZ domain-containing protein KCTD10, Potassium channel tetramerization... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 35.4 kD |
From 1,185.00€
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Human SHKB1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120707.10
Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.[UniProtKB/Swiss-Prot Function]. Human SHKB1-Strep full length...
| Keywords: | PP203, SHKBP1, SETA-binding protein 1, SH3KBP1-binding protein 1 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 76.3 kD |
From 1,185.00€
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Human CA2D4-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120708.10
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio....
| Keywords: | CACNA2D4 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 127.9 kD |
From 1,185.00€
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Human CXB4-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120710.10
This gene encodes a transmembrane connexin protein that is a component of gap junctions. Mutations in this gene have been associated with erythrokeratodermia variabilis, progressive symmetric erythrokeratoderma and hearing impairment. [provided by RefSeq, Dec 2009]. Human CXB4-Strep full length protein-synthetic...
| Keywords: | GJB4, Cx30.3, Connexin-30.3, Gap junction beta-4 protein |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 30.4 kD |
From 1,185.00€
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Human KCD18-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120711.10
. Human KCD18-Strep full length protein-synthetic nanodisc.
| Keywords: | KCTD18, BTB/POZ domain-containing protein KCTD18 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 46.7 kD |
From 1,185.00€
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Human BEST3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120712.10
BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD, MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing...
| Keywords: | BEST3, VMD2L3, Bestrophin-3, Vitelliform macular dystrophy 2-like protein 3 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 76.1 kD |
From 1,185.00€
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Human KCD11-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120713.10
Plays a role as a marker and a regulator of neuronal differentiation, Up-regulated by a variety of neurogenic signals, such as retinoic acid, epidermal growth factor/EGF and NGFB/nerve growth factor. Induces apoptosis, growth arrest and the expression of cyclin-dependent kinase inhibitor CDKN1B. Plays a role as a...
| Keywords: | KCTD11, C17orf36, KCASH1 protein, BTB/POZ domain-containing protein KCTD11, RING-type E3 ubiquitin transferase subunit... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 25.9 kD |
From 1,185.00€
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