Human BEST3-Strep full length protein-synthetic nanodisc

Item number	Size	Manual	SDS	Delivery time	Price
DIM-FLP120712.10	10 µg	-	-	7 - 16 business days*	1,185.00€
DIM-FLP120712.50	50 µg	-	-	7 - 16 business days*	5,793.00€
DIM-FLP120712.100	100 µg	-	-	7 - 16 business days*	10,534.00€

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BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the... more

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Product information "Human BEST3-Strep full length protein-synthetic nanodisc"

BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD, MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738], Tsunenari et al., 2003 [PubMed 12907679]).[supplied by OMIM, Mar 2008]. Human BEST3-Strep full length protein-synthetic nanodisc. Protein function: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. [The UniProt Consortium]

Keywords:	BEST3, VMD2L3, Bestrophin-3, Vitelliform macular dystrophy 2-like protein 3
Supplier:	DIMA
Supplier-Nr:	FLP120712

Properties

Application:	Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization
Conjugate:	No
Host:	Human cells
Species reactivity:	human
MW:	76.1 kD
Format:	Lyophilized

Database Information

KEGG ID :	K13880 \| Matching products
UniProt ID :	Q8N1M1 \| Matching products
Gene ID :	GeneID 144453 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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