Anti-phospho-LIMK2 (Thr505)

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABE-35-1123-50 50 µl -

3 - 11 Werktage*

574,00 €
 
Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in... mehr
Produktinformationen "Anti-phospho-LIMK2 (Thr505)"
Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro. Protein function: Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics (PubMed:10436159, PubMed:11018042). Acts downstream of several Rho family GTPase signal transduction pathways (PubMed:10436159, PubMed:11018042). Involved in astral microtubule organization and mitotic spindle orientation during early stages of mitosis by mediating phosphorylation of TPPP (PubMed:22328514). Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro (PubMed:8537403). Suppresses ciliogenesis via multiple pathways, phosphorylation of CFL1, suppression of directional trafficking of ciliary vesicles to the ciliary base, and by facilitating YAP1 nuclear localization where it acts as a transcriptional corepressor of the TEAD4 target genes AURKA and PLK1 (PubMed:25849865). [The UniProt Consortium]
Schlagworte: Anti-phospho-LIMK2, Anti-phospho-LIMK-2, Anti-phospho-LIM domain kinase 2, Polyclonal Antibody to LIMK2 (Phospho-Thr505)
Hersteller: Abeomics
Hersteller-Nr: 35-1123-50

Eigenschaften

Anwendung: WB, IHC, IF
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
Immunogen: Peptide sequence around phosphorylation site of threonine 505 (R-Y-T(p)-V-V) derived from Human LIMK2.
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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