Allgemeine Primärantikörper

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Anti-Desmin
Anti-Desmin

Artikelnummer: NSJ-R31530

0.5mg/ml if reconstituted with 0.2ml sterile DI water. DES, also called Desmin, is a protein that in humans is encoded by the DES gene, and this gene is mapped to 2q35. DES is a member of the intermediate filament (IF) protein family. It is one of the earliest myogenic markers, both in heart and somites, and is...
Schlagworte: Anti-DES, Anti-Desmin, Desmin Antibody
Anwendung: WB, IHC (paraffin), IF
Reaktivität: Human, Mouse, Rat
549,00 €
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Anti-Active Cdc42, monoclonal
Anti-Active Cdc42, monoclonal

Artikelnummer: NB-26905

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Small GTPases are a super-family of cellular signaling regulators. Cdc42 belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity...
Schlagworte: Anti-CDC42, Anti-G25K GTP-binding protein, Anti-Cell division control protein 42 homolog
Anwendung: IP, IHC
Reaktivität: Vertebrates
669,00 €
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Anti-ZBP1, clone Zippy-1
Anti-ZBP1, clone Zippy-1

Artikelnummer: AG-20B-0010-C100

Recognizes human and mouse ZBP1. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. ZBP1 binds to cytoplasmic DNA and plays a role in host defense against tumors and pathogens. Highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow and spleen.
Schlagworte: Z-DNA-binding Protein 1, Tumor Stroma and Activated Macrophage Protein DLM-1, DNA-dependent Activator of IFN-regulatory...
Anwendung: IP, WB
Reaktivität: Human , Mouse
429,00 €
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Anti-DDB1
Anti-DDB1

Artikelnummer: A300-462A

Protein function: Required for DNA repair. Binds to DDB2 to form the UV- damaged DNA-binding protein complex (the UV-DDB complex). The UV- DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. The UV-DDB complex...
Schlagworte: Anti-XPCe, Anti-DDB1, Anti-DDBa, Anti-XAP1, Anti-XAP-1, Anti-XPE-BF, Anti-UV-DDB 1, Anti-DDB p127 subunit,...
Anwendung: WB, IP, IHC
Reaktivität: Human, Mouse
ab 131,00 €
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Anti-ASH2
Anti-ASH2

Artikelnummer: A300-489A

Protein function: Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone...
Schlagworte: Anti-ASH2L, Anti-ASH2L1, Anti-ASH2-like protein, Anti-Set1/Ash2 histone methyltransferase complex subunit ASH2
Anwendung: WB, IP, IHC, ChIP, ChIP-chip
Reaktivität: Human
465,00 €
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Anti-KIAA0310
Anti-KIAA0310

Artikelnummer: A300-648A

Protein function: Defines endoplasmic reticulum exit sites (ERES) and is required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining an ERES. Required for normal transitional endoplasmic...
Schlagworte: Anti-SEC16A, Anti-KIAA0310, Anti-SEC16 homolog A, Anti-Protein transport protein Sec16A
Anwendung: WB, IP
Reaktivität: Human
ab 131,00 €
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Anti-NELFE
Anti-NELFE

Artikelnummer: A301-913A

Protein function: Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. [The UniProt...
Schlagworte: Anti-RD, Anti-NELFE, Anti-NELF-E, Anti-RNA-binding protein RD, Anti-Negative elongation factor E
Anwendung: WB, IP
Reaktivität: Human
ab 131,00 €
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Anti-SHANK3
Anti-SHANK3

Artikelnummer: A304-178A

Protein function: Major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation, maturation and maintenance. Interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via...
Schlagworte: Anti-Shank3, Anti-SHANK3, Anti-ProSAP2, Anti-KIAA1650, Anti-Proline-rich synapse-associated protein 2, Anti-SH3 and...
Anwendung: WB, IP
Reaktivität: Human, Mouse
ab 131,00 €
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Anti-ZNF451
Anti-ZNF451

Artikelnummer: A305-177A

Protein function: E3 SUMO-protein ligase, has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins (PubMed:26524493, PubMed:26524494). Plays a role in protein SUMO2 modification in response to stress caused by DNA damage and by proteasome inhibitors (in vitro). Required...
Schlagworte: Anti-ZNF451, Anti-Zinc finger protein 451, Anti-E3 SUMO-protein ligase ZNF451, Anti-Coactivator for steroid receptors
Anwendung: WB, IP
Reaktivität: Human
ab 131,00 €
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Anti-p73
Anti-p73

Artikelnummer: A300-126A

Protein function: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. [The UniProt Consortium]
Schlagworte: Anti-P73, Anti-TP73, Anti-Tumor protein p73, Anti-p53-related protein, Anti-p53-like transcription factor
Anwendung: WB, IP
Reaktivität: Human
ab 131,00 €
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Anti-RbBP5
Anti-RbBP5

Artikelnummer: A300-109A

Protein function: In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid. Does not affect ES cell self-renewal. Component or...
Schlagworte: Anti-RBQ3, Anti-RBBP5, Anti-RBBP-5, Anti-Retinoblastoma-binding protein 5, Anti-Retinoblastoma-binding protein RBQ-3
Anwendung: WB, IP, IHC, ICC, ChIP, ChIP-chip
Reaktivität: Human
ab 131,00 €
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Anti-HdmX/MDM4
Anti-HdmX/MDM4

Artikelnummer: A300-287A

Protein function: Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions. [The UniProt Consortium]
Schlagworte: Anti-MDM4, Anti-MDMX, Anti-Protein Mdm4, Anti-Protein Mdmx, Anti-Double minute 4 protein, Anti-p53-binding protein Mdm4,...
Anwendung: WB, IP
Reaktivität: Human
ab 131,00 €
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