PTM-spezifische Antikörper

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Anti-phospho-ATG13 (Ser318)
Anti-phospho-ATG13 (Ser318)

Artikelnummer: 600-401-C49

Protein function: Autophagy factor required for autophagosome formation. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. [The UniProt Consortium]
Anwendung: ELISA, WB, FC
Antikörper-Typ: Polyclonal
Wirt: Rabbit
Reaktivität: Human
Format: Antigen Affinity Purified
458,00 €
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Anti-phospho-EGF-Receptor (Tyr1086), clone 8B8
Anti-phospho-EGF-Receptor (Tyr1086), clone 8B8

Artikelnummer: 0188-100

Anwendung: WB, ELISA
Antikörper-Typ: Monoclonal
Wirt: Mouse
Reaktivität: Human
MW: 180 kD
Format: Purified
349,00 €
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Anti-phospho-AKT (Ser473), clone 17F6.B11
Anti-phospho-AKT (Ser473), clone 17F6.B11

Artikelnummer: 200-301-268S

Protein function: AKT1 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have...
Anwendung: ELISA, WB, IHC
Antikörper-Typ: Monoclonal
Wirt: Mouse
Reaktivität: Human, Mouse
Format: Purified
ab 130,00 €
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Anti-phospho-ATM Protein Kinase (Ser1981), clone 10H11.E12
Anti-phospho-ATM Protein Kinase (Ser1981),...

Artikelnummer: 200-301-400S

Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs),...
Anwendung: ELISA, WB, IP, IF
Antikörper-Typ: Monoclonal
Wirt: Mouse
Reaktivität: Human, Mouse, Rat
Format: IgG
ab 130,00 €
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Anti-phospho-ATM Protein  Kinase (Ser1981), clone  7C10D8
Anti-phospho-ATM Protein Kinase (Ser1981),...

Artikelnummer: 200-301-500

Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs),...
Anwendung: ELISA, WB, IHC, FC
Antikörper-Typ: Monoclonal
Wirt: Mouse
Reaktivität: Human, Mouse
534,00 €
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Anti-phospho-Histone H2AvD (Ser137)
Anti-phospho-Histone H2AvD (Ser137)

Artikelnummer: 600-401-914

Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is...
Anwendung: ELISA, WB, IHC
Antikörper-Typ: Polyclonal
Wirt: Rabbit
Reaktivität: Drosophila
MW: 14 kD
Format: Affinity Purified
458,00 €
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Anti-phospho-VASP (Ser239), clone 16C2
Anti-phospho-VASP (Ser239), clone 16C2

Artikelnummer: 0047-100

Does not cross-react with the non-phosphorylated form of VASP nor with unrelated serine-phosphorylated proteins.
Anwendung: WB, ELISA, IP, ICC, FC
Antikörper-Typ: Monoclonal
Wirt: Mouse
Reaktivität: Human, Mouse
MW: 46/50 kD
Format: Purified
390,00 €
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Anti-phospho-VASP (Ser157), clone 5C6
Anti-phospho-VASP (Ser157), clone 5C6

Artikelnummer: 0085-100

Does not cross-react with the non-phosphorylated form of protein.
Anwendung: WB, ELISA, IP, ICC, FC
Antikörper-Typ: Monoclonal
Wirt: Mouse
Reaktivität: Human, Mouse
MW: 46/50 kD
Format: Purified
390,00 €
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Anti-phospho-EZH2 (Ser21) (IHC)
Anti-phospho-EZH2 (Ser21) (IHC)

Artikelnummer: IHC-00388

Protein function: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys- 27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing...
Anwendung: IHC
Antikörper-Typ: Polyclonal
Wirt: Rabbit
Reaktivität: Human, Mouse
Format: Antigen Affinity Purified
ab 125,00 €
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Anti-gamma-H2AX
Anti-gamma-H2AX

Artikelnummer: A300-081A

Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is...
Anwendung: WB, IHC, ICC/IF
Antikörper-Typ: Polyclonal
Wirt: Rabbit
Reaktivität: Human, Mouse
Format: Antigen Affinity Purified
ab 125,00 €
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Anti-phospho-RPA32 (Ser4/Ser8)
Anti-phospho-RPA32 (Ser4/Ser8)

Artikelnummer: A300-245A-T

Protein function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA...
Anwendung: WB, IP, IHC, ICC/IF
Antikörper-Typ: Polyclonal
Wirt: Rabbit
Reaktivität: Human, Mouse
Format: Antigen Affinity Purified
ab 125,00 €
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Anti-phospho-RPA32 (Ser33)
Anti-phospho-RPA32 (Ser33)

Artikelnummer: A300-246A

Protein function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA...
Anwendung: WB
Antikörper-Typ: Polyclonal
Wirt: Rabbit
Reaktivität: Human
Format: Antigen Affinity Purified
ab 125,00 €
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