PTM-spezifische Antikörper

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Anti-phospho-ATM Protein Kinase (Ser1981), clone 10H11.E12
Anti-phospho-ATM Protein Kinase (Ser1981), clone 10H11.E12

Artikelnummer: 200-301-400

Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of...
Schlagworte: Anti-phospho-ATM, Anti-phospho-A-T mutated, EC=2.7.11.1, Anti-phospho-Serine-protein kinase ATM, Anti-phospho-Ataxia...
Anwendung: ELISA, FC, IHC, IFM, WB
Wirt: Mouse
Spezies-Reaktivität: human, mouse, rat
ab 180,00 €
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Anti-Polyglutamylation Modification, clone GT335
Anti-Polyglutamylation Modification, clone GT335

Artikelnummer: AG-20B-0020-C100

Recognizes the posttranslational modification (poly)glutamylation on proteins. Reacts with polyglutamylated alpha- and beta-tubulin. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Polyglutamylation is a post-translational modification in which glutamate side chains of variable lengths are formed on...
Schlagworte: Polyglutamylated Tubulin, Glutamylated Tubulin, Postranslational Protein Glutamylation
Anwendung: ICC, IP, WB, IHC (paraffin), IEM
Wirt: Mouse
Spezies-Reaktivität: All
451,00 €
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Anti-phospho-RPA32 (Ser4/Ser8)
Anti-phospho-RPA32 (Ser4/Ser8)

Artikelnummer: A300-245A

Protein function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA...
Schlagworte: Anti-phospho-RPA2, Anti-phospho-REPA2, Anti-phospho-RP-A p34, Anti-phospho-RP-A p32, Anti-phospho-RF-A protein 2,...
Anwendung: WB, IP, IHC, ICC-IF
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 164,00 €
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Anti-phospho-RPA32 (Ser33)
Anti-phospho-RPA32 (Ser33)

Artikelnummer: A300-246A

Protein function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA...
Schlagworte: Anti-phospho-RPA2, Anti-phospho-REPA2, Anti-phospho-RP-A p34, Anti-phospho-RP-A p32, Anti-phospho-RF-A protein 2,...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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Anti-phospho-KAP-1 (Ser824)
Anti-phospho-KAP-1 (Ser824)

Artikelnummer: A300-767A

Protein function: Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of...
Schlagworte: Anti-phospho-KAP1, Anti-phospho-KAP-1, Anti-phospho-TRIM28, Anti-phospho-KRIP-1, Anti-phospho-TIF1-beta, EC=6.3.2.-,...
Anwendung: WB, IP, IHC, ICC, ICC-IF
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 164,00 €
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Anti-phospho-VASP (Ser239), clone 16C2
Anti-phospho-VASP (Ser239), clone 16C2

Artikelnummer: 0047-100

Does not cross-react with the non-phosphorylated form of VASP nor with unrelated serine-phosphorylated proteins.
Schlagworte: (pS239) Anti-phospho-VASP, Anti-phospho-VASP, Anti-phospho-Vasodilator-stimulated phosphoprotein
Anwendung: WB, ELISA, IP, ICC, FC
Wirt: Mouse
Spezies-Reaktivität: human, mouse
428,00 €
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Anti-phospho-RNA Polymerase II (Ser2)
Anti-phospho-RNA Polymerase II (Ser2)

Artikelnummer: A300-654A

Protein function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together...
Schlagworte: Anti-phospho-POLR2, Anti-phospho-POLR2A, EC=2.7.7.6, EC=2.7.7.48, Anti-phospho-RNA polymerase II subunit B1,...
Anwendung: WB, IP, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 164,00 €
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Anti-phospho-BRCA1 (Ser1189)
Anti-phospho-BRCA1 (Ser1189)

Artikelnummer: A300-003A-T

BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity....
Schlagworte: Anti-phospho-BRCA1, Anti-phospho-RNF53, Anti-phospho-RING finger protein 53, Anti-phospho-RING-type E3 ubiquitin...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human
164,00 €
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Anti-phospho-BRCA1 (Ser1280)
Anti-phospho-BRCA1 (Ser1280)

Artikelnummer: A300-004A-T

BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity....
Schlagworte: Anti-phospho-BRCA1, Anti-phospho-RNF53, Anti-phospho-RING finger protein 53, Anti-phospho-RING-type E3 ubiquitin...
Anwendung: WB, IP
Wirt: Rabbit
Spezies-Reaktivität: human
164,00 €
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Anti-phospho-XRCC1 (Ser518/Thr519/Thr523)
Anti-phospho-XRCC1 (Ser518/Thr519/Thr523)

Artikelnummer: A300-059A-T

X-ray repair cross-complementing protein 1 (XRCC1) has been identified as a gene that partially rescues a DNA repair defect and therefore plays a role in efficient repair of single-stranded breaks in DNA damage caused by ionizing radiation. XRCC1 interacts with human polynucleotide kinase, DNA polymerase-beta, and...
Schlagworte: Anti-phospho-X-ray repair cross complementing protein 1 variant
Anwendung: WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
164,00 €
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Anti-phospho-XRCC1 (Ser461)
Anti-phospho-XRCC1 (Ser461)

Artikelnummer: A300-147A-T

X-ray repair cross-complementing protein 1 (XRCC1) has been identified as a gene that partially rescues a DNA repair defect and therefore plays a role in efficient repair of single-stranded breaks in DNA damage caused by ionizing radiation. XRCC1 interacts with human polynucleotide kinase, DNA polymerase-beta, and...
Schlagworte: Anti-phospho-X-ray repair cross complementing protein 1 variant
Anwendung: WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
164,00 €
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Anti-phospho-RNA Polymerase II (Ser2)
Anti-phospho-RNA Polymerase II (Ser2)

Artikelnummer: A304-407A-T

RNA polymerase II is a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. RNA polymerase II subunit B1 (RPB1) is the largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional...
Schlagworte: Anti-phospho-POLR2, EC=2.7.7.6, EC=2.7.7.48, Anti-phospho-RNA polymerase II subunit B1, Anti-phospho-DNA-directed RNA...
Anwendung: WB, IP, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
164,00 €
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