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Anti-Polyglutamylation Modification, clone GT335
Artikelnummer: AG-20B-0020-C100
Recognizes the posttranslational modification (poly)glutamylation on proteins. Reacts with polyglutamylated alpha- and beta-tubulin. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Polyglutamylation is a post-translational modification in which glutamate side chains of variable lengths are formed on...
| Schlagworte: | Polyglutamylated Tubulin, Glutamylated Tubulin, Postranslational Protein Glutamylation |
| Anwendung: | ICC, IP, WB, IHC (paraffin), IEM |
| Wirt: | Mouse |
| Spezies-Reaktivität: | All |
473,00 €
Anti-phospho-RPA32 (Ser4/Ser8)
Artikelnummer: A300-245A
Protein function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA...
| Schlagworte: | Anti-phospho-RPA2, Anti-phospho-REPA2, Anti-phospho-RP-A p34, Anti-phospho-RP-A p32, Anti-phospho-RF-A protein 2,... |
| Anwendung: | WB, IP, IHC, ICC-IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Anti-phospho-RPA32 (Ser33)
Artikelnummer: A300-246A
Protein function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA...
| Schlagworte: | Anti-phospho-RPA2, Anti-phospho-REPA2, Anti-phospho-RP-A p34, Anti-phospho-RP-A p32, Anti-phospho-RF-A protein 2,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-phospho-KAP-1 (Ser824)
Artikelnummer: A300-767A
Protein function: Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of...
| Schlagworte: | Anti-phospho-KAP1, Anti-phospho-KAP-1, Anti-phospho-TRIM28, Anti-phospho-KRIP-1, Anti-phospho-TIF1-beta, EC=6.3.2.-,... |
| Anwendung: | WB, IP, IHC, ICC, ICC-IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Anti-phospho-ATM Protein Kinase (Ser1981), clone 10H11.E12
Artikelnummer: 200-301-400
Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of...
| Schlagworte: | Anti-phospho-ATM, Anti-phospho-A-T mutated, EC=2.7.11.1, Anti-phospho-Serine-protein kinase ATM, Anti-phospho-Ataxia... |
| Anwendung: | ELISA, FC, IHC, IFM, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
ab 180,00 €
Anti-phospho-RNA Polymerase II (Ser2)
Artikelnummer: A300-654A
Protein function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together...
| Schlagworte: | Anti-phospho-POLR2, Anti-phospho-POLR2A, EC=2.7.7.6, EC=2.7.7.48, Anti-phospho-RNA polymerase II subunit B1,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
![Anti-Polyglutamate chain [Poly-E]](https://www.biomol.com/media/image/e5/f7/cf/AG-25B-0030-C050_200x200.png "Anti-Polyglutamate chain [Poly-E]")
Anti-Polyglutamate chain [Poly-E]
Artikelnummer: AG-25B-0030-C050
Tubulin polyglutamylation stimulates spastin-mediated microtubule severing. Microtubules are key elements of the eukaryotic cytoskeleton that dynamically assemble from heterodimers of alpha- and beta-tubulin. Two different mechanisms can generate microtubule diversity: the expression of different alpha- and...
| Schlagworte: | Anti-Poly-E, pAb (IN105), Anti-Poly-Glu |
| Anwendung: | WB, ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | broad |
440,00 €
NEU
Anti-Pan Methylated Lysine, monoclonal
Artikelnummer: ELK-EM1186.100
Many proteins are post translationally modified. Modifications such as phosphorylation, glycosylation, ubiquitination and methylation have been shown to play an important role in the development, physiology and disease of animals and plants.
| Schlagworte: | Pan Methylated Lysine Mouse mAb |
| Anwendung: | WB, IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | broad |
ab 173,00 €
NEU
Anti-Phosphoserine, monoclonal
Artikelnummer: ELK-EM1189.100
| Schlagworte: | Phosphoserine Mouse mAb |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | broad |
ab 173,00 €
NEU
Anti-Acetyl Lysine, monoclonal
Artikelnummer: ELK-EM1191.100
Acetylation of lysine, like phosphorylation of serine, threonine or tyrosine, is an important reversible modification controlling protein activity. The role of acetylation in intracellular signaling has been inferred from the binding of acetylated peptides by the conserved bromodomain.
| Schlagworte: | Acetyl Lysine Mouse mAb |
| Anwendung: | WB, IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | broad |
ab 173,00 €
NEU
Anti-Phosphotyrosine, monoclonal
Artikelnummer: ELK-EM1194.100
The phosphorylation of specific tyrosine residues has been shown to be a primary mechanism of signal transduction during normal mitogenesis, cell cycle progression and oncogenic transformation, its role in other areas such as differentiation and gap junction communication, is a matter of active and ongoing research.
| Schlagworte: | Phosphotyrosine Mouse mAb |
| Anwendung: | WB, IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | broad |
ab 173,00 €
NEU
Anti-phospho-CaMKIIbeta/gamma/delta (Thr287), monoclonal
Artikelnummer: ELK-EM1222.100
CaMKII is an important member of the calcium/calmodulin-activated protein kinase family, functioning in neural synaptic stimulation and T-cell receptor signaling. CaMKII has catalytic and regulatory domains. Protein Function: Calcium/calmodulin-dependent protein kinase that functions autonomously after...
| Schlagworte: | Anti-phospho-CAMK2B, Anti-phospho-Calcium/calmodulin-dependent protein kinase type II subunit beta, CaMKIIbeta/gamma/delta... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, rat, mouse |
ab 173,00 €