PTM-spezifische Antikörper

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Anti-phospho-Histone H3 (Ser10) (IHC)
Anti-phospho-Histone H3 (Ser10) (IHC)

Artikelnummer: IHC-00061

Protein function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA...
Schlagworte: Anti-phospho-H3FL, Anti-phospho-H3FF, Anti-phospho-H3FK, Anti-phospho-H3FI, Anti-phospho-H3FB, Anti-phospho-H3FD,...
Anwendung: IHC, ICC/IF
Reaktivität: Human, Mouse
ab 131,00 €
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Anti-phospho-AKT (Ser473), clone 17F6.B11
Anti-phospho-AKT (Ser473), clone 17F6.B11

Artikelnummer: 200-301-268S

Protein function: AKT1 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range...
Schlagworte: Anti-phospho-PKB, Anti-phospho-AKT1, Anti-phospho-PKB alpha, EC=2.7.11.1, Anti-phospho-RAC-PK-alpha, Anti-phospho-Protein...
Anwendung: ELISA, WB, IHC
Reaktivität: Human, Mouse
ab 132,00 €
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Anti-phospho-ATM Protein Kinase (Ser1981), clone 10H11.E12
Anti-phospho-ATM Protein Kinase (Ser1981), clone 10H11.E12

Artikelnummer: 200-301-400

Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of...
Schlagworte: Anti-phospho-ATM, Anti-phospho-A-T mutated, EC=2.7.11.1, Anti-phospho-Serine-protein kinase ATM, Anti-phospho-Ataxia...
Anwendung: ELISA, WB, IP, IF
Reaktivität: Human, Mouse, Rat
ab 132,00 €
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Anti-phospho-ATM Protein Kinase (Ser1981), clone 7C10D8
Anti-phospho-ATM Protein Kinase (Ser1981), clone 7C10D8

Artikelnummer: 200-301-500

Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of...
Schlagworte: Anti-phospho-ATM, Anti-phospho-A-T mutated, EC=2.7.11.1, Anti-phospho-Serine-protein kinase ATM, Anti-phospho-Ataxia...
Anwendung: ELISA, WB, IHC, FC
Reaktivität: Human, Mouse
590,00 €
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Anti-phospho-Histone H2AvD (Ser137)
Anti-phospho-Histone H2AvD (Ser137)

Artikelnummer: 600-401-914

Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA...
Schlagworte: Anti-phospho-H2AvD, Anti-phospho-H2A.Z, Anti-phospho-His2Av, Anti-phospho-CG5499, Anti-phospho-H2A.F/Z,...
Anwendung: ELISA, WB, IHC
Reaktivität: Drosophila
506,00 €
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Anti-phospho-Histone H2AvD (Ser137)
Anti-phospho-Histone H2AvD (Ser137)

Artikelnummer: 600-401-914S

This affinity purified anti-Histone H2AvD pS137 Antibody is directed against the phosphorylated form of Drosophila H2AvD protein at the pS137 residue. The product was affinity purified from monospecific antiserum by immunoaffinity purification. Antiserum was first purified against the phosphorylated form of the...
Schlagworte: Anti-phospho-H2AvD, Anti-phospho-H2A.Z, Anti-phospho-CG5499, Anti-phospho-His2Av, Anti-phospho-H2A.F/Z,...
Anwendung: ELISA, WB, IHC
Reaktivität: Drosophila
132,00 €
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Anti-phospho-ATG13 (Ser318)
Anti-phospho-ATG13 (Ser318)

Artikelnummer: 600-401-C49

Protein function: Autophagy factor required for autophagosome formation. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. [The UniProt Consortium]
Schlagworte: Anti-phospho-ATG13, Anti-phospho-KIAA0652, Anti-phospho-Autophagy-related protein 13
Anwendung: ELISA, WB, FC
Reaktivität: Human
506,00 €
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Anti-phospho-PPAR gamma (Ser273)
Anti-phospho-PPAR gamma (Ser273)

Artikelnummer: 600-401-J94

Anti-PPAR gamma pS273 was affinity purified from monospecific antiserum by immunoaffinity chromatography. A BLAST analysis was used to suggest cross-reactivity with rat, mouse, primate, human, dog, bovine, and pig based on 100% sequence homology. Cross-reactivity with PPAR gamma pS273 from other sources has not been...
Schlagworte: Anti-phospho-PPARG, Anti-phospho-NR1C3, Anti-phospho-PPAR-gamma, Anti-phospho-Nuclear receptor subfamily 1 group C member...
Anwendung: ELISA, WB
Reaktivität: Human
506,00 €
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Anti-phospho-VASP (Ser239), clone 16C2
Anti-phospho-VASP (Ser239), clone 16C2

Artikelnummer: 0047-100

Does not cross-react with the non-phosphorylated form of VASP nor with unrelated serine-phosphorylated proteins.
Schlagworte: (pS239) Anti-phospho-VASP, Anti-phospho-VASP, Anti-phospho-Vasodilator-stimulated phosphoprotein
Anwendung: WB, ELISA, IP, ICC, FC
Reaktivität: Human, Mouse
390,00 €
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Anti-phospho-VASP (Ser157), clone 5C6
Anti-phospho-VASP (Ser157), clone 5C6

Artikelnummer: 0085-100

Does not cross-react with the non-phosphorylated form of protein.
Schlagworte: (pS157) Anti-phospho-VASP, Anti-phospho-VASP, Anti-phospho-Vasodilator-stimulated phosphoprotein
Anwendung: WB, ELISA, IP, ICC, FC
Reaktivität: Human, Mouse
390,00 €
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Anti-Polyglutamylation Modification, clone GT335
Anti-Polyglutamylation Modification, clone GT335

Artikelnummer: AG-20B-0020-C100

Recognizes the posttranslational modification (poly)glutamylation on proteins. Reacts with polyglutamylated alpha- and beta-tubulin. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Polyglutamylation is a post-translational modification in which glutamate side chains of variable lengths are formed on...
Schlagworte: Polyglutamylated Tubulin, Glutamylated Tubulin, Postranslational Protein Glutamylation
Anwendung: ICC, IP, WB
Reaktivität: All
418,00 €
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Anti-Polyglutamate chain [Poly-E]
Anti-Polyglutamate chain [Poly-E]

Artikelnummer: AG-25B-0030-C050

Tubulin polyglutamylation stimulates spastin-mediated microtubule severing. Microtubules are key elements of the eukaryotic cytoskeleton that dynamically assemble from heterodimers of alpha- and beta-tubulin. Two different mechanisms can generate microtubule diversity: the expression of different alpha- and...
Schlagworte: Anti-Poly-E, pAb (IN105), Anti-Poly-Glu
Anwendung: WB, ICC
Reaktivität: Broad
385,00 €
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