PTM-spezifische Antikörper

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Anti-phospho-RPA32 (Ser33)
Anti-phospho-RPA32 (Ser33)

Artikelnummer: A300-246A

Protein function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA...
Schlagworte: Anti-phospho-RPA2, Anti-phospho-REPA2, Anti-phospho-RP-A p34, Anti-phospho-RP-A p32, Anti-phospho-RF-A protein 2,...
Anwendung: WB
Reaktivität: Human
ab 131,00 €
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Anti-Polyglutamylation Modification, clone GT335
Anti-Polyglutamylation Modification, clone GT335

Artikelnummer: AG-20B-0020-C100

Recognizes the posttranslational modification (poly)glutamylation on proteins. Reacts with polyglutamylated alpha- and beta-tubulin. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Polyglutamylation is a post-translational modification in which glutamate side chains of variable lengths are formed on...
Schlagworte: Polyglutamylated Tubulin, Glutamylated Tubulin, Postranslational Protein Glutamylation
Anwendung: ICC, IP, WB
Reaktivität: All
418,00 €
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Anti-phospho-KAP-1 (Ser824)
Anti-phospho-KAP-1 (Ser824)

Artikelnummer: A300-767A

Protein function: Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of...
Schlagworte: Anti-phospho-KAP1, Anti-phospho-KAP-1, Anti-phospho-TRIM28, Anti-phospho-KRIP-1, Anti-phospho-TIF1-beta, EC=6.3.2.-,...
Anwendung: WB, IP, IHC, ICC, ICC/IF
Reaktivität: Human, Mouse
ab 131,00 €
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Anti-phospho-RPA32 (Ser4/Ser8)
Anti-phospho-RPA32 (Ser4/Ser8)

Artikelnummer: A300-245A

Protein function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA...
Schlagworte: Anti-phospho-RPA2, Anti-phospho-REPA2, Anti-phospho-RP-A p34, Anti-phospho-RP-A p32, Anti-phospho-RF-A protein 2,...
Anwendung: WB, IP, IHC, ICC/IF
Reaktivität: Human, Mouse
ab 131,00 €
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Anti-phospho-VASP (Ser239), clone 16C2
Anti-phospho-VASP (Ser239), clone 16C2

Artikelnummer: 0047-100

Does not cross-react with the non-phosphorylated form of VASP nor with unrelated serine-phosphorylated proteins.
Schlagworte: (pS239) Anti-phospho-VASP, Anti-phospho-VASP, Anti-phospho-Vasodilator-stimulated phosphoprotein
Anwendung: WB, ELISA, IP, ICC, FC
Reaktivität: Human, Mouse
390,00 €
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Anti-phospho-RNA Polymerase II (Ser2)
Anti-phospho-RNA Polymerase II (Ser2)

Artikelnummer: A300-654A

Protein function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together...
Schlagworte: Anti-phospho-POLR2, Anti-phospho-POLR2A, EC=2.7.7.6, EC=2.7.7.48, Anti-phospho-RNA polymerase II subunit B1,...
Anwendung: WB, IP, IHC
Reaktivität: Human, Mouse
ab 131,00 €
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Anti-phospho-ATM Protein Kinase (Ser1981), clone 10H11.E12
Anti-phospho-ATM Protein Kinase (Ser1981), clone 10H11.E12

Artikelnummer: 200-301-400

The antibody detects a single 370kDa protein in crude extracts prepared either from irradiated human foreskin or mouse 3T3L1 fibroblasts. No reactivity is detected against mock-irradiated cell extracts.
Schlagworte: Anti-phospho-ATM (pS1981), EC=2.7.11.1, Anti-phospho-A-T mutated, Anti-phospho-Serine-protein kinase ATM,...
Anwendung: ELISA, FC, IHC, IFM, WB
Reaktivität: Human, Mouse, Rat
ab 132,00 €
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Anti-phospho-CDKN2A (Ser8)
Anti-phospho-CDKN2A (Ser8)

Artikelnummer: NSJ-F48749-0.08ML

In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase....
Schlagworte: Anti-phospho-MTS-1, Anti-phospho-CDKN2, Anti-phospho-CDK4I, Anti-phospho-p16-INK4, Anti-phospho-p16INK4A,...
Anwendung: DB, ELISA
Reaktivität: Human
ab 228,00 €
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Anti-eIF2alpha (Phospho-Ser51) Rabbit
Anti-eIF2alpha (Phospho-Ser51) Rabbit

Artikelnummer: Cay32244-100

eIF2alpha is the alpha subunit of eukaryotic inhibition factor 2, which also includes eIF2beta and eIF2gamma subunits and is involved in the initiation of translation. eIF2alpha is composed of a globular N-terminal domain, which contains an S1 domain and an alpha-helical domain, and a globular C-terminal domain....
Schlagworte: Eukaryotic Translation Initiation Factor 2 Subunit 1
Anwendung: IHC, WB
432,00 €
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Anti-gamma-H2AX
Anti-gamma-H2AX

Artikelnummer: A300-081A

Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA...
Schlagworte: Anti-H2AX, Anti-H2AFX, Anti-H2a/x, Anti-Histone H2AX, Anti-Histone H2A.X
Anwendung: WB, IHC, ICC/IF
Reaktivität: Human, Mouse
ab 131,00 €
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Anti-phospho-Histone H2AvD (Ser137)
Anti-phospho-Histone H2AvD (Ser137)

Artikelnummer: 600-401-914

Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA...
Schlagworte: Anti-phospho-H2AvD, Anti-phospho-H2A.Z, Anti-phospho-His2Av, Anti-phospho-CG5499, Anti-phospho-H2A.F/Z,...
Anwendung: ELISA, IHC, WB
Reaktivität: Drosophila
506,00 €
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50% auf den zweiten Artikel
Anti-acetyl-Histone H4-K12
Anti-acetyl-Histone H4-K12

Artikelnummer: E-AB-66253.120

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker...
Schlagworte: Anti-acetyl-H4C8, Anti-acetyl-H4C9, Anti-acetyl-H4C5, Anti-acetyl-H4C6, Anti-acetyl-H4C2, Anti-acetyl-H4C4,...
Anwendung: IHC, IF
Reaktivität: Human, Mouse, Rat
ab 181,00 €
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