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PTM-spezifische Antikörper

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Anti-phospho-RNA Polymerase II (Ser2)
Anti-phospho-RNA Polymerase II (Ser2)

Artikelnummer: A300-654A

Protein function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together...
Schlagworte: Anti-phospho-POLR2, Anti-phospho-POLR2A, EC=2.7.7.6, EC=2.7.7.48, Anti-phospho-RNA polymerase II subunit B1,...
Anwendung: WB, IP, IHC
Reaktivität: Human, Mouse
ab 125,00 €
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Anti-citrulinated-Citrullinated Myelin Basic Protein
Anti-citrulinated-Citrullinated Myelin Basic Protein

Artikelnummer: Cay26742-500

Citrullinated myelin basic protein (citMBP) is a citrullinated form of MBP, a protein that is integral to myelin stability in the CNS. MBP contains 19 arginine residues that can be citrullinated by peptidylarginine deiminases (PADs), decreasing the positive charge of MBP. The loss of positive charge disrupts...
Schlagworte: Anti-citrulinated-MBP, Anti-citrulinated-Myelin A1 protein, Anti-citrulinated-Myelin basic protein,...
Anwendung: ELISA, WB
Reaktivität: Human
499,00 €
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Anti-citrulinated-AGE (GA-Pyridine Specific) (Clone 1F10)
Anti-citrulinated-AGE (GA-Pyridine Specific) (Clone 1F10)

Artikelnummer: Cay27271-100

Glycolaldehyde-pyridine (GA-pyridine) is an advanced glycation end product (AGE). It is formed via the reaction of GA, a product of myeloperoxidase activity, with lysine and can therefore serve as an antigenic marker of protein modification resulting from myeloperoxidase activity. GA-pyridine has been detected in...
Schlagworte: Anti-Advanced Glycation End Products (Glycolaldehyde-pyridine)
Anwendung: ELISA, WB
Reaktivität: Human
412,00 €
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NEU
Anti-phospho-CD104 / Integrin beta 4 (Tyr1494)
Anti-phospho-CD104 / Integrin beta 4 (Tyr1494)

Artikelnummer: ARG23944.50

Protein function: Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling...
Schlagworte: Anti-phospho-CD104, Anti-phospho-GP150, Anti-phospho-ITGB4, Anti-phospho-Integrin beta-4
Anwendung: ICC, IF, WB
Reaktivität: Human
439,00 €
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NEU
Anti-phospho-CD104 / Integrin beta 4 (Tyr1526)
Anti-phospho-CD104 / Integrin beta 4 (Tyr1526)

Artikelnummer: ARG23945.50

Protein function: Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling...
Schlagworte: Anti-phospho-CD104, Anti-phospho-GP150, Anti-phospho-ITGB4, Anti-phospho-Integrin beta-4
Anwendung: ICC, IF, WB
Reaktivität: Human
439,00 €
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NEU
Anti-phospho-CDK1 / CDC2 (Tyr15)
Anti-phospho-CDK1 / CDC2 (Tyr15)

Artikelnummer: ARG41124.50

Protein function: Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset, promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and...
Schlagworte: Anti-phospho-CDC2, Anti-phospho-CDK1, EC=2.7.11.22, EC=2.7.11.23, Anti-phospho-p34 protein kinase,...
Anwendung: ICC, IF, IP, WB
Reaktivität: Human
439,00 €
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NEU
Anti-phospho-CDK2 (Tyr15)
Anti-phospho-CDK2 (Tyr15)

Artikelnummer: ARG41143.100

Protein function: Serine/threonine-protein kinase involved in the control of the cell cycle, essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F...
Schlagworte: Anti-phospho-CDK2, Anti-phospho-CDKN2, Anti-phospho-p33 protein kinase, Anti-phospho-Cyclin-dependent kinase 2,...
Anwendung: IHC (paraffin), IP, WB
Reaktivität: Human, Mouse, Rat
483,00 €
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NEU
Anti-phospho-PLC gamma 1 (Ser1248)
Anti-phospho-PLC gamma 1 (Ser1248)

Artikelnummer: ARG41204.50

Protein function: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand- mediated activation of receptor-type tyrosine kinases, such...
Schlagworte: Anti-phospho-PLC1, Anti-phospho-PLCG1, Anti-phospho-PLC-II, Anti-phospho-PLC-148, Anti-phospho-PLC-gamma-1, EC=3.1.4.11,...
Anwendung: IHC (paraffin), WB
Reaktivität: Human
439,00 €
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NEU
Anti-phospho-RIP3 (Ser304)
Anti-phospho-RIP3 (Ser304)

Artikelnummer: ARG41234.100

Protein function: Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic...
Schlagworte: Anti-phospho-Rip3, Anti-phospho-Ripk3, Anti-phospho-RIP-3, Anti-phospho-mRIP3, EC=2.7.11.1, Anti-phospho-RIP-like protein...
Anwendung: WB
Reaktivität: Mouse
483,00 €
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NEU
Anti-phospho-RIP3 (Ser232)
Anti-phospho-RIP3 (Ser232)

Artikelnummer: ARG41235.100

Protein function: Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic...
Schlagworte: Anti-phospho-Rip3, Anti-phospho-Ripk3, Anti-phospho-RIP-3, Anti-phospho-mRIP3, EC=2.7.11.1, Anti-phospho-RIP-like protein...
Anwendung: WB
Reaktivität: Mouse
483,00 €
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NEU
Anti-phospho-BCAR1 / p130 Cas (Tyr762)
Anti-phospho-BCAR1 / p130 Cas (Tyr762)

Artikelnummer: ARG41253.50

Protein function: Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. [The UniProt Consortium]
Schlagworte: Anti-phospho-Cas, Anti-phospho-Bcar1, Anti-phospho-p130cas, Anti-phospho-CRK-associated substrate, Anti-phospho-Breast...
Anwendung: WB
Reaktivität: Human
439,00 €
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NEU
Anti-phospho-BCAR1 / p130 Cas (Tyr751)
Anti-phospho-BCAR1 / p130 Cas (Tyr751)

Artikelnummer: ARG41254.50

Protein function: Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. [The UniProt Consortium]
Schlagworte: Anti-phospho-Cas, Anti-phospho-Bcar1, Anti-phospho-p130cas, Anti-phospho-CRK-associated substrate, Anti-phospho-Breast...
Anwendung: WB
Reaktivität: Human
439,00 €
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