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Anti-Polyglutamylation Modification, clone GT335
Artikelnummer: AG-20B-0020-C100
Recognizes the posttranslational modification (poly)glutamylation on proteins. Reacts with polyglutamylated alpha- and beta-tubulin. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Polyglutamylation is a post-translational modification in which glutamate side chains of variable lengths are formed on...
| Schlagworte: | Polyglutamylated Tubulin, Glutamylated Tubulin, Postranslational Protein Glutamylation |
| Anwendung: | ICC, IP, WB, IHC (paraffin), IEM |
| Wirt: | Mouse |
| Spezies-Reaktivität: | All |
473,00 €
Anti-phospho-RPA32 (Ser4/Ser8)
Artikelnummer: A300-245A
Protein function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA...
| Schlagworte: | Anti-phospho-RPA2, Anti-phospho-REPA2, Anti-phospho-RP-A p34, Anti-phospho-RP-A p32, Anti-phospho-RF-A protein 2,... |
| Anwendung: | WB, IP, IHC, ICC-IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Anti-phospho-RPA32 (Ser33)
Artikelnummer: A300-246A
Protein function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA...
| Schlagworte: | Anti-phospho-RPA2, Anti-phospho-REPA2, Anti-phospho-RP-A p34, Anti-phospho-RP-A p32, Anti-phospho-RF-A protein 2,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-phospho-KAP-1 (Ser824)
Artikelnummer: A300-767A
Protein function: Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of...
| Schlagworte: | Anti-phospho-KAP1, Anti-phospho-KAP-1, Anti-phospho-TRIM28, Anti-phospho-KRIP-1, Anti-phospho-TIF1-beta, EC=6.3.2.-,... |
| Anwendung: | WB, IP, IHC, ICC, ICC-IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Anti-phospho-ATM Protein Kinase (Ser1981), clone 10H11.E12
Artikelnummer: 200-301-400
Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of...
| Schlagworte: | Anti-phospho-ATM, Anti-phospho-A-T mutated, EC=2.7.11.1, Anti-phospho-Serine-protein kinase ATM, Anti-phospho-Ataxia... |
| Anwendung: | ELISA, FC, IHC, IFM, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
ab 180,00 €
Anti-phospho-RNA Polymerase II (Ser2)
Artikelnummer: A300-654A
Protein function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together...
| Schlagworte: | Anti-phospho-POLR2, Anti-phospho-POLR2A, EC=2.7.7.6, EC=2.7.7.48, Anti-phospho-RNA polymerase II subunit B1,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
![Anti-Polyglutamate chain [Poly-E]](https://www.biomol.com/media/image/e5/f7/cf/AG-25B-0030-C050_200x200.png "Anti-Polyglutamate chain [Poly-E]")
Anti-Polyglutamate chain [Poly-E]
Artikelnummer: AG-25B-0030-C050
Tubulin polyglutamylation stimulates spastin-mediated microtubule severing. Microtubules are key elements of the eukaryotic cytoskeleton that dynamically assemble from heterodimers of alpha- and beta-tubulin. Two different mechanisms can generate microtubule diversity: the expression of different alpha- and...
| Schlagworte: | Anti-Poly-E, pAb (IN105), Anti-Poly-Glu |
| Anwendung: | WB, ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | broad |
440,00 €
Anti-gamma-H2AX
Artikelnummer: A300-081A
Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA...
| Schlagworte: | Anti-H2AX, Anti-H2AFX, Anti-H2a/x, Anti-Histone H2AX, Anti-Histone H2A.X |
| Anwendung: | WB, IHC, ICC-IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Anti-phospho-eIF4EBP1 (Thr46) / Eukaryotic translation...
Artikelnummer: NSJ-FY12420
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-eIF4EBP1 (Thr46) antibody detects eukaryotic translation initiation factor 4E binding protein 1 when phosphorylated at threonine 46. EIF4EBP1 is encoded by the EIF4EBP1 gene and is part of a...
| Schlagworte: | Anti-phospho-EIF4EBP1, Anti-phospho-Eukaryotic translation initiation factor 4E-binding protein 1,... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
790,00 €
Anti-phospho-Chk1 (Ser280) / Checkpoint kinase 1, clone...
Artikelnummer: NSJ-FY12496
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-Chk1 (Ser280) antibody detects checkpoint kinase 1 when phosphorylated at serine 280. Chk1 is a serine threonine kinase encoded by the CHEK1 gene and functions as a key regulator of the DNA...
| Schlagworte: | Anti-phospho-CHEK1, Anti-phospho-Checkpoint kinase-1, Anti-phospho-CHK1 checkpoint homolog, Anti-phospho-Cell cycle... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
Anti-phospho-c-Jun/JunD (Ser73/Ser100), clone 30J61
Artikelnummer: NSJ-FY12568
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-c-Jun/JunD (Ser73/Ser100) antibody detects the phosphorylated forms of c-Jun and JunD, transcription factors belonging to the activator protein 1 (AP-1) family. c-Jun, encoded by the JUN gene,...
| Schlagworte: | Anti-phospho-p39, Anti-phospho-JUN, Anti-phospho-Activator protein 1, Anti-phospho-Proto-oncogene c-Jun,... |
| Anwendung: | WB, IHC, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
790,00 €
Anti-phospho-PKC (Ser729) / PRKCA/PRKCB/PRKCE, clone 32P75
Artikelnummer: NSJ-FY12683
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-PKC (Ser729) antibody detects protein kinase C when phosphorylated at serine 729. Protein kinase C belongs to a family of serine threonine kinases encoded by multiple genes including PRKCA,...
| Schlagworte: | Anti-phospho-PRKCE, Anti-phospho-nPKC-epsilon, Anti-phospho-Protein kinase C epsilon type, Phospho-PKC (Ser729) Antibody /... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
790,00 €