Zu "K05744" wurden 41 Artikel gefunden!
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TH-257
Artikelnummer: TGM-T7128-5mg
Description: TH-257 is a Potent and selective allosteric LIMK 1/2 inhibitor(LIMK1 and LIMK2, IC50 of 84 nM and 39 nM). Target: LIM Kinase. Smiles: CCCCN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1. References: Fabrizio M . Recent advances in the rational design and development of LIM kinase inhibitors are not enough...
| Schlagworte: | TH 257 |
| Anwendung: | LIMK1 / LIMK2 inhibitor |
| CAS | 2244678-29-1 |
| MW: | 422.54 D |
ab 37,00 €
LX7101 hydrochloride
Artikelnummer: TGM-T85304-10mg
Description: LX7101 is a potent inhibitor of both LIM kinase (LIMK) 1 and 2, and Rho-associated kinase 1 (ROCK1) and ROCK2, with IC50 values of 32, 4.3, 69, and 32 nM, respectively. It is selective, demonstrated by its lack of cross-reactivity in a panel of binding assays involving 78 receptors, transporters, and an...
| Anwendung: | LIMK2 inhibitor |
| CAS | 2319882-48-7 |
| MW: | 488 D |
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BMS-5
Artikelnummer: TGM-T4598-100mg
Description: BMS-5 (LIMKi 3) is a highly potent LIMK inhibitor, exhibiting IC50 values of 7 nM for LIMK1 and 8 nM for LIMK2. Target: LIM Kinase. Smiles: CC(C)C(=O)Nc1ncc(s1)-c1cc(nn1-c1c(Cl)cccc1Cl)C(F)F. References: Ross-Macdonald P, et al. Identification of a nonkinase target mediating cytotoxicity of novel kinase...
| Schlagworte: | BMS5, LIMKi 3 |
| Anwendung: | LIMK1 / LIMK2 inhibitor |
| CAS | 1338247-35-0 |
| MW: | 431.29 D |
ab 37,00 €
Anti-LIMK2
Artikelnummer: CSB-PA003152.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-LIMK2, Anti-LIMK-2, Anti-LIM domain kinase 2, LIM domain kinase 2 antibody, LIM kinase 2 antibody, LIMK 2 antibody,... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-LIMK2
Artikelnummer: CSB-PA009832.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-LIMK2, Anti-LIMK-2, Anti-LIM domain kinase 2, LIM domain kinase 2 antibody, LIM kinase 2 antibody, LIMK 2 antibody,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-LIMK2
Artikelnummer: CSB-PA009833.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-LIMK2, Anti-LIMK-2, Anti-LIM domain kinase 2, LIM domain kinase 2 antibody, LIM kinase 2 antibody, LIMK 2 antibody,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-Phospho-LIMK2 (T505)
Artikelnummer: CSB-PA000567.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-LIMK2, Anti-phospho-LIMK-2, Anti-phospho-LIM domain kinase 2, LIM domain kinase 2 antibody, LIM kinase 2... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-Phospho-LIMK2 (Thr505)
Artikelnummer: CSB-PA555443.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
| Schlagworte: | Anti-phospho-LIMK2, Anti-phospho-LIMK-2, Anti-phospho-LIM domain kinase 2, LIM domain kinase 2 antibody, LIM kinase 2... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
340,00 €
Anti-LIMK2
Artikelnummer: CSB-PA891322.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-LIMK2, Anti-LIMK-2, Anti-LIM domain kinase 2, LIM domain kinase 2 antibody, LIM kinase 2 antibody, LIMK 2 antibody,... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
283,00 €
Anti-LIMK2 (Ab-283)
Artikelnummer: CSB-PA903894.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-LIMK2, Anti-LIMK-2, Anti-LIM domain kinase 2, LIM domain kinase 2 antibody, LIM kinase 2 antibody, LIMK 2 antibody,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
283,00 €
BMS-5
Artikelnummer: SYN-1024-M001
Soluble in DMSO. Kinases, such as LIM kinase 1 (LIMK1) and LIM kinase 2 (LIMK2), have been identified as participating in signal pathways affecting actin dynamics by deactivating cofilin. Over expression of LMK1 has been found in invasive breast and prostate cancer cell lines and suppression of LIMK 2 expression has...
| Schlagworte: | BMS5 |
| Anwendung: | LIMK1 / LIMK2 inhibitor |
| CAS | 1338247-35-0 |
| MW: | 431,3 D |
ab 123,00 €
BMS-5
Artikelnummer: Cay21072-1
BMS-5 is a potent inhibitor of activated LIM domain kinases LIMK1 and LIMK2 with IC50 values of 7 and 8 nM, respectively. LIMK1 and LIMK2 participate in signal pathways affecting actin dynamics by deactivating cofilin. This compound can be used to study the role of activated LIMK isoforms in the signaling of Rho...
| Schlagworte: | LIM Kinase Inhibitor I, LIMKi 3,... |
| Anwendung: | LIMK1 / LIMK2 inhibitor |
| CAS | 1338247-35-0 |
| MW: | 431.3 D |
ab 66,00 €