Anti-phospho-EIF4E (Ser209) (Eukaryotic Translation Initiation Factor 4E, eIF4E, eIF-4E, mRNA Cap-bi

Anti-phospho-EIF4E (Ser209) (Eukaryotic Translation Initiation Factor 4E, eIF4E, eIF-4E, mRNA Cap-bi
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E8949-40N-PE.200 200 µl - -

4 - 22 Werktage

696,00 €
 
eIF4F is a multi-subunit complex, the composition of which varies with external and internal... mehr
Produktinformationen "Anti-phospho-EIF4E (Ser209) (Eukaryotic Translation Initiation Factor 4E, eIF4E, eIF-4E, mRNA Cap-bi"
eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. EIF4E is also known to interact with other partners. The interaction with EIF4ENIF1 mediates the import into the nucleus. Nonphosphorylated EIF4EBP1, EIF4EBP2 and EIF4EBP3 compete with EIF4G1/EIF4G3 to interact with EIF4E, insulin stimulated MAP-kinase (MAPK1 and MAPK3) phosphorylation of EIF4EBP1 causes dissociation of the complex allowing EIF4G1/EIF4G3 to bind and consequent initiation of translation. Rapamycin can attenuate insulin stimulation, mediated by FKBPs. Applications: Suitable for use in FLISA and Dot Blot. Other applications not tested. Recommended Dilution: FLISA: 1:1,000 , Dot Blot: 1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light., , Note: Applications are based on unconjugated antibody.
Schlagworte: Anti-phospho-eIF4E, Anti-phospho-EIF4E, Anti-phospho-eIF-4E, Anti-phospho-EIF4EL1, Anti-phospho-eIF-4F 25 kDa subunit, Anti-phospho-mRNA cap-binding protein, Anti-phospho-Eukaryotic translation initiation factor 4E
Hersteller: United States Biological
Hersteller-Nr: E8949-40N-PE

Eigenschaften

Anwendung: FLISA, Dot Blot
Antikörper-Typ: Polyclonal
Wirt: Rabbit
Reaktivität: Human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser209 of human EIF4E (KLH).
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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