Zu "K03259" wurden 124 Artikel gefunden!
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Eukaryotic translation initiation factor 4E (EIF4E),...
Artikelnummer: CSB-YP007556HU.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 2-217aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: ATVEPETTPT PNPPTTEEEK TESNQEVANP EHYIKHPLQN RWALWFFKND KSKTWQANLR LISKFDTVED FWALYNHIQL SSNLMPGCDY SLFKDGIEPM WEDEKNKRGG RWLITLNKQQ...
| Schlagworte: | eIF4E, eIF-4E, EIF4EL1, eIF-4F 25 kDa subunit, mRNA cap-binding protein, Eukaryotic translation initiation factor 4E |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | human |
| MW: | 26.5 kD |
ab 242,00 €
4E1rcat
Artikelnummer: TGM-T1742-100mg
Description: 4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 µM. Target: PERK, Autophagy. Smiles: OC(=O)c1ccc(cc1)N1C(=O)\C(=C\c2ccc(o2)-c2ccc(cc2)[N+]([O-])=O)C=C1c1ccccc1. References: Shuda M, et al. Proc Natl Acad Sci U S...
| Anwendung: | Protein translation inhibitor, eIF4E:eIF4G & eIF4E:4E-BP1 interaction inhibitor |
| CAS | 328998-25-0 |
| MW: | 478.45 D |
ab 46,00 €
4E2RCat
Artikelnummer: TGM-T14044-100mg
Description: 4E2RCat is an inhibitor of eIF4E-eIF4G interaction (IC50 = 13.5 µM) and effectively blocks coronavirus replication, as evidenced by reduced viral protein expression and decreased production of infectious virus. Target: PERK. Smiles: OC(=O)c1cc(ccc1Cl)-c1ccc(\C=C2/SC(=S)N(Cc3ccccc3)C2=O)o1. References:...
| Anwendung: | eIF4E-eIF4G protein-protein interaction inhibitor |
| CAS | 432499-63-3 |
| MW: | 455.93 D |
ab 58,00 €
Briciclib
Artikelnummer: TGM-T3207-100mg
Description: Briciclib (ON 014185) is a small molecule that inhibits cyclin D1 accumulation in Y cells. Target: PERK, Autophagy, CDK. Smiles: C(=C/S(CC1=CC(OP(=O)(O)O)=C(OC)C=C1)(=O)=O)\C2=C(OC)C=C(OC)C=C2OC. References: Neel Jasani, et al. DOI: 10.1158/1538-7445.
| Schlagworte: | ON 014185 |
| Anwendung: | Targets translation initiation factor 4E (EIF4E) |
| CAS | 865783-99-9 |
| MW: | 474.42 D |
ab 40,00 €
4EGI-1
Artikelnummer: TGM-T2665-1mg
Description: 4EGI-1, a competitive eIF4E/eIF4 g interaction inhibitor, binds to eIF4E(KD=25 µM). Target: Apoptosis, PERK, Autophagy. Smiles: OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N\Nc1nc(cs1)-c1ccc(Cl)c(Cl)c1. References: Moerke NJ, et al. Cell. 2007, 128(2), 257-267.
| Schlagworte: | 4EGI 1 |
| Anwendung: | Translation initiation inhibitor |
| CAS | 315706-13-9 |
| MW: | 451.28 D |
ab 38,00 €
Briciclib Na
Artikelnummer: TGM-T68506-100mg
Description: Briciclib Na inhibits benzylstyryl sulfone kinase and is use for the treatment of Cancer. Target: Others
| Anwendung: | Targets translation initiation factor 4E (EIF4E) |
| CAS | 865784-01-6 |
| MW: | 518.38 D |
ab 1.520,00 €
Anti-EIF4E
Artikelnummer: CSB-PA002308.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-eIF4E, Anti-eIF-4E, Anti-EIF4EL1, Anti-eIF-4F 25 kDa subunit, Anti-mRNA cap-binding protein, Anti-Eukaryotic... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
126,00 €
Anti-Phospho-EIF4E (S209)
Artikelnummer: CSB-PA000519.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-eIF4E, Anti-phospho-eIF-4E, Anti-phospho-EIF4EL1, Anti-phospho-eIF-4F 25 kDa subunit, Anti-phospho-mRNA... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-EIF4E (Ab-209)
Artikelnummer: CSB-PA190338.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
| Schlagworte: | Anti-eIF4E, Anti-eIF-4E, Anti-EIF4EL1, Anti-eIF-4F 25 kDa subunit, Anti-mRNA cap-binding protein, Anti-Eukaryotic... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
283,00 €
Anti-Phospho-EIF4E (Ser209)
Artikelnummer: CSB-PA935753.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
| Schlagworte: | Anti-phospho-eIF4E, Anti-phospho-eIF-4E, Anti-phospho-EIF4EL1, Anti-phospho-eIF-4F 25 kDa subunit, Anti-phospho-mRNA... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
340,00 €
4EGI-1
Artikelnummer: Cay15362-1
In eukaryotes, a set of initiation factors (eIFs) interact with ribosomal subunits to initiate mRNA translation. A major step in initiation is the assembly of a large multiprotein complex that includes the cap-binding protein eIF4E and the multidomain adaptor protein eIF4G. 4EGI-1 is an inhibitor of the initiation...
| Schlagworte: | eIF4E/eIF4G Interaction Inhibitor, alpha-[2-[4-(3,4-dichlorophenyl)-2-thiazolyl]hydrazinylidene]-2-nitro-benzenepropanoic... |
| Anwendung: | Translation initiation inhibitor |
| CAS | 315706-13-9 |
| MW: | 451.3 D |
ab 61,00 €
Anti-eIF4E
Artikelnummer: A301-154A
Protein function: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and...
| Schlagworte: | Anti-eIF4E, Anti-EIF4E, Anti-eIF-4E, Anti-EIF4EL1, Anti-eIF-4F 25 kDa subunit, Anti-mRNA cap-binding protein,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 178,00 €