Anti-EIF4E

Anti-EIF4E
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-F47410-0.08ML 80 µl - -

3 - 10 Werktage*

326,00 €
NSJ-F47410-0.4ML 400 µl - -

3 - 10 Werktage*

702,00 €
 
In 1X PBS, pH 7.4, with 0.09% sodium azide. eIF4F is a multi-subunit complex, the composition of... mehr
Produktinformationen "Anti-EIF4E"
In 1X PBS, pH 7.4, with 0.09% sodium azide. eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. EIF4E is also known to interact with other partners. The interaction with EIF4ENIF1 mediates the import into the nucleus. Nonphosphorylated EIF4EBP1, EIF4EBP2 and EIF4EBP3 compete with EIF4G1/EIF4G3 to interact with EIF4E, insulin stimulated MAP-kinase (MAPK1 and MAPK3) phosphorylation of EIF4EBP1 causes dissociation of the complex allowing EIF4G1/EIF4G3 to bind and consequent initiation of translation. Rapamycin can attenuate insulin stimulation, mediated by FKBPs. this gene also interacts mutually exclusive with EIF4A1 and EIF4A2. Protein function: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap. [The UniProt Consortium]
Schlagworte: Anti-eIF4E, Anti-EIF4E, Anti-eIF-4E, Anti-EIF4EL1, Anti-eIF-4F 25 kDa subunit, Anti-mRNA cap-binding protein, Anti-Eukaryotic translation initiation factor 4E, EIF4E Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: F47410

Eigenschaften

Anwendung: WB, IHC, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: A portion of amino acids 32-61 from the human protein was used as the immunogen for this EIF4E antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Anti-EIF4E"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen