Anti-PDPK1, phosphorylated Ser396 (3-phosphoinositide Dependent Protein Kinase-1, hPDK1, PDK1) (Azid

Anti-PDPK1, phosphorylated Ser396 (3-phosphoinositide Dependent Protein Kinase-1, hPDK1, PDK1) (Azid
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
P3123-02F-HRP.200 200 µl - -

3 - 19 Werktage*

993,00 €
 
PDPK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDPK1 activates... mehr
Produktinformationen "Anti-PDPK1, phosphorylated Ser396 (3-phosphoinositide Dependent Protein Kinase-1, hPDK1, PDK1) (Azid"
PDPK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDPK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDPK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase, and the stimulation of glycogen synthesis. Because of the role that PDPK1 plays in insulin-induced glycogen synthesis and PKC activation, it is a potentially important target for metabolic drug research. Applications: Suitable for use in ELISA and Dot Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 , Dot Blot: 1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Hersteller: United States Biological
Hersteller-Nr: P3123-02F-HRP

Eigenschaften

Anwendung: ELISA, Dot Blot
Antikörper-Typ: Polyclonal
Konjugat: HRP
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser396 of human PDPK1 (KLH).
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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