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Zu "K06276" wurden 86 Artikel gefunden!
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Artikelnummer: ELK-ELK6179.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PDPK1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PDPK1. Next,...
Schlagworte: | Pdk1, mPDK1, Pdpk1, EC=2.7.11.1, 3-phosphoinositide-dependent protein kinase 1 |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
ab 365,00 €
Artikelnummer: Cay18095-5
3-Phosphoinositide-dependent protein kinase 1 (PDK1) is a serine-threonine kinase that plays an important role in growth factor signaling by phosphorylating and activating a group of kinases, including protein kinase (PK)B, PKA, and certain isoforms of PKC. GSK2334470 is an inhibitor of PDK1 (IC50 = ~10 nM) that...
Schlagworte: | (3S,6R)-1-[6-(3-amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-3-piperidinecarboxamide |
Anwendung: | PDPK1 inhibitor |
CAS | 1227911-45-6 |
MW: | 462.6 D |
ab 102,00 €
Artikelnummer: AG-CR1-0056-M001
Phosphoinositide-dependent kinase 1 (PDK1) inhibitor, Potent, reversible and ATP-competitive glycogen synthase kinase-3alpha/beta (GSK-3alpha/beta) inhibitor, JAK/STAT3 signaling inhibitor, Apoptosis inducer, Potent antiproliferative agent in malignant lymphoid cell.
Schlagworte: | 2Z,3E)-6-Bromoindirubin-3-oxime |
Anwendung: | PDPK1 inhibitor |
CAS | 667463-62-9 |
MW: | 356,2 D |
ab 39,00 €
Artikelnummer: Cay15399-10
Xanthohumol is a natural prenylated chalcone isolated from the hop plant, H. lupulus. Xanthohumol and its metabolites induce protective detoxification enzymes, at least in part via the nuclear factor erythroid-2-related factor 2 pathway. It inhibits phosphoinositide-dependent kinase 1 (IC50 = 6.6 µM) but not PKC in...
Schlagworte: | (2E)-1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one |
Anwendung: | PDPK1 inhibitor |
CAS | 6754-58-1 |
MW: | 354.4 D |
ab 32,00 €
Artikelnummer: Cay14932-5
BX-795 is a multi-kinase inhibitor that is an ATP-competitive inhibitor of 3-phosphoinositide-dependent protein kinase 1 (PDK1) and TANK-binding kinase 1 (TBK1, IC50s = 6 and 11 nM, respectively). It also inhibits the CAMK family kinases AMPK-related kinase 5 (NUAK1, IC50 = 5 nM) and microtubule affinity-regulating...
Schlagworte: | N-[3-[[5-iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide |
Anwendung: | PDPK1 inhibitor |
CAS | 702675-74-9 |
MW: | 591.5 D |
ab 109,00 €
Artikelnummer: LKT-G7344.5
GSK2334470 is a potent 3-phosphoinositide-dependent protein kinase (PDK1) inhibitor (IC50 ~ 10 nM).
Schlagworte: | GSK-2334470,... |
Anwendung: | PDPK1 inhibitor |
CAS | 1227911-45-6 |
MW: | 462.59 D |
ab 90,00 €
Artikelnummer: Cay14708-1
3-Phosphoinositide-dependent protein kinase 1 (PDK1) is a serine-threonine kinase that phosphorylates and activates a range of other kinases, including protein kinase (PK)B, PKA, and certain isoforms of PKC. BX-912 is a potent, ATP-competitive inhibitor of PDK1 (IC50 = 26 nM). It less effectively inhibits a panel of...
Schlagworte: | N-[3-[[5-bromo-4-[[2-(1H-imidazol-5-yl)ethyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide |
Anwendung: | PDK1 inhibitor |
CAS | 702674-56-4 |
MW: | 471.4 D |
ab 61,00 €
Artikelnummer: SYN-1026-M001
Soluble in DMSO or ethanol. BX795 was initially developed as a PDK1 inhibitor (direct competitive inhibitor IC(50) 11nM for PDK1) and has been shown to be a potent and relatively specific inhibitor of TBK1 and IKK-epsilon. It blocks the phosphorylation, nuclear translocation, and transcriptional activity of...
Schlagworte: | BX795 |
Anwendung: | PDPK1 inhibitor |
CAS | 702675-74-9 |
MW: | 591,5 D |
ab 100,00 €
Artikelnummer: Cay10008005-10
Cyclooxygenase-2 (COX-2) appears to play a significant role in the development and progression of cancer and COX-2 inhibitors such as celecoxib exhibit anti-cancer activity. OSU03012 is an analog of celecoxib that exhibits anti-cancer activity in a COX-2-independent manner via inhibition of the phosphatidyl...
Schlagworte: | 2-amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-acetamide |
Anwendung: | PDK1 (PDPK1) inhibitor |
CAS | 742112-33-0 |
MW: | 460.5 D |
ab 98,00 €
Artikelnummer: ARG51005.100
Protein function: Serine/threonine kinase which acts as a master kinase, phosphorylating and activating a subgroup of the AGC family of protein kinases. Its targets include: protein kinase B (PKB/AKT1, PKB/AKT2, PKB/AKT3), p70 ribosomal protein S6 kinase (RPS6KB1), p90 ribosomal protein S6 kinase (RPS6KA1, RPS6KA2...
Schlagworte: | Anti-PDK1, Anti-hPDK1, Anti-PDPK1, EC=2.7.11.1, Anti-3-phosphoinositide-dependent protein kinase 1 |
Anwendung: | ICC, IF, IHC (paraffin), WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 436,00 €
Artikelnummer: ARG51509.100
Protein function: Serine/threonine kinase which acts as a master kinase, phosphorylating and activating a subgroup of the AGC family of protein kinases. Its targets include: protein kinase B (PKB/AKT1, PKB/AKT2, PKB/AKT3), p70 ribosomal protein S6 kinase (RPS6KB1), p90 ribosomal protein S6 kinase (RPS6KA1, RPS6KA2...
Schlagworte: | Anti-phospho-PDK1, Anti-phospho-hPDK1, Anti-phospho-PDPK1, EC=2.7.11.1, Anti-phospho-3-phosphoinositide-dependent protein... |
Anwendung: | ICC, IF, IHC (paraffin), WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 436,00 €
Artikelnummer: A302-130A
Protein function: Serine/threonine kinase which acts as a master kinase, phosphorylating and activating a subgroup of the AGC family of protein kinases. Its targets include: protein kinase B (PKB/AKT1, PKB/AKT2, PKB/AKT3), p70 ribosomal protein S6 kinase (RPS6KB1), p90 ribosomal protein S6 kinase (RPS6KA1, RPS6KA2...
Schlagworte: | Anti-PDK1, Anti-hPDK1, Anti-PDPK1, EC=2.7.11.1, Anti-3-phosphoinositide-dependent protein kinase 1 |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 164,00 €