Anti-USP14

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
A300-919A-T 10 µl (10 µg) -

2 - 8 Werktage*

164,00 €
A300-919A 100 µl (100 µg) -

2 - 8 Werktage*

588,00 €
 
Protein function: Proteasome-associated deubiquitinase which releases ubiquitin from the... mehr
Produktinformationen "Anti-USP14"
Protein function: Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs). Plays a role in the innate immune defense against viruses by stabilizing the viral DNA sensor CGAS and thus inhibiting its autophagic degradation. [The UniProt Consortium]
Schlagworte: Anti-TGT, Anti-USP14, EC=3.4.19.12, Anti-Ubiquitin thioesterase 14, Anti-Deubiquitinating enzyme 14, Anti-Ubiquitin carboxyl-terminal hydrolase 14, Anti-Ubiquitin-specific-processing protease 14
Hersteller: Bethyl Laboratories
Hersteller-Nr: A300-919A

Eigenschaften

Anwendung: WB, IP, IHC
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human (Erwartet: chimpanzee)
Immunogen: synthetic peptide. The epitope recognized by A300-919A-T maps to a region between residue 350 and 400 of human Ubiquitin Specific Peptidase 14 using the numbering given in entry NP_005142.1 (GeneID 9097).
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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