Zu "K11843" wurden 56 Artikel gefunden!
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Anti-USP14
Artikelnummer: ATA-HPA074815.100
Rabbit Polyclonal USP14 Antibody against Human ubiquitin specific peptidase 14. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000047879: 93%,...
| Schlagworte: | Anti-TGT, Anti-USP14, EC=3.4.19.12, Anti-Ubiquitin thioesterase 14, Anti-Deubiquitinating enzyme 14, Anti-Ubiquitin... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 369,00 €
IU1
Artikelnummer: Cay10617-10
Polybiquitinylation designates proteins for proteasomal degradation. USP14 is one of several deubiquitinating enzymes (DUBs) responsible for shortening proteasome-bound ubiquitin chains, which is known to antagonize the degradation of ubiquitin-protein conjugates. IU1 is a reversible, small molecule inhibitor of...
| Schlagworte: | 1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)-ethanone |
| Anwendung: | Deubiquitination inhibitor |
| CAS | 314245-33-5 |
| MW: | 300.4 D |
ab 57,00 €
Anti-USP14
Artikelnummer: A300-920A
Protein function: Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell....
| Schlagworte: | Anti-TGT, Anti-USP14, EC=3.4.19.12, Anti-Ubiquitin thioesterase 14, Anti-Deubiquitinating enzyme 14, Anti-Ubiquitin... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
USP14, active human recombinant protein, N-terminal FLAG-tag
Artikelnummer: BPS-80364
Human USP14 (Ubiquitin-Specific Protease 14) or TGT (tRNA-guanine transglycosylase), GenBank Accession No. NM_005151, amino-acids 2-494(end) with an N-terminal FLAG-tag, MW=57 kDa, expressed in a baculovirus-infected Sf9 cell expression system.
| Schlagworte: | TGT, USP14, EC=3.4.19.12, Ubiquitin thioesterase 14, Deubiquitinating enzyme 14, Ubiquitin carboxyl-terminal hydrolase 14,... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Baculovirus |
| Ursprungsart: | human |
| MW: | 57 kD |
640,00 €
WP1130
Artikelnummer: Cay15227-5
Protein ubiquitination is a dynamic process that can be reversed by deubiquitinating enzymes (DUBs) that remove ubiquitin from proteins, sparing them from degradation by the proteasome. The DUBs have been divided into two subgroups: ubiquitin-specific proteases (USPs) and ubiquitin-specific COOH-terminal hydrolases...
| Schlagworte: | Degrasyn, (2E)-3-(6-bromo-2-pyridinyl)-2-cyano-N-[1S-phenylbutyl]-2-propenamide |
| Anwendung: | Tyrphostin derivate, deubiquitinase activity inhibitor |
| CAS | 856243-80-6 |
| MW: | 384.3 D |
ab 102,00 €
Anti-USP14
Artikelnummer: A300-919A
Protein function: Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell....
| Schlagworte: | Anti-TGT, Anti-USP14, EC=3.4.19.12, Anti-Ubiquitin thioesterase 14, Anti-Deubiquitinating enzyme 14, Anti-Ubiquitin... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
b-AP15
Artikelnummer: Cay11324-1
Proteasome-associated deubiquitinases (DUBs) release ubiquitin from proteasome-targeted ubiquitinated proteins, regenerating free ubiquitin. b-AP15 is an inhibitor of ubiquitin-specific-processing protease 14 (USP14) and ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCHL5), two proteasome-associated DUBs. It...
| Schlagworte: | 3E,5E-bis[(4-nitrophenyl)methylene]-1-(1-oxo-2-propen-1-yl)-4-piperidinone |
| Anwendung: | USP14 / UCHL5 inhibitor |
| CAS | 1009817-63-3 |
| MW: | 419.4 D |
ab 56,00 €
IU1
Artikelnummer: BPS-27227
IU1 is a small molecule, reversible inhibitor of deubiquitination by USP14. It selectively stimulates ubiquitin-dependent protein degradation in vitro at 34 µM and in MEF cells at 50 µM. IU1 can also reduce accumulation of oxidized proteins in HEK293 cells, which alleviates cytotoxicity induced by oxidative stress.
| Schlagworte: | 1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone, |
| Anwendung: | USP14 inhibitor |
| MW: | 300.4 D |
346,00 €
Anti-USP14, clone 889CT6.2.1
Artikelnummer: ARG54999.100
Protein function: Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell....
| Schlagworte: | Anti-TGT, Anti-USP14, EC=3.4.19.12, Anti-Ubiquitin thioesterase 14, Anti-Deubiquitinating enzyme 14, Anti-Ubiquitin... |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
616,00 €
Anti-USP14
Artikelnummer: ARG41670.100
Protein function: Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell....
| Schlagworte: | Anti-TGT, Anti-USP14, EC=3.4.19.12, Anti-Ubiquitin thioesterase 14, Anti-Deubiquitinating enzyme 14, Anti-Ubiquitin... |
| Anwendung: | FC, ICC, IF, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
658,00 €
Anti-USP14
Artikelnummer: E-AB-18519.120
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that...
| Schlagworte: | Anti-TGT, Anti-USP14, EC=3.4.19.12, Anti-Ubiquitin thioesterase 14, Anti-Deubiquitinating enzyme 14, Anti-Ubiquitin... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 89,00 €
VLX1570
Artikelnummer: Cay29721-1
VLX1570 is an inhibitor of 19S proteasomal deubiquitinases with IC50 values of 6.4 and 13 µM for deubiquitinase activity in vitro using Ub-rhodamine and Ub-AMC, respectively, as substrates. It is selective for proteasomal deubiquitinases over a panel of deubiquitinases at 20 µM, but inhibits USP5 by greater than...
| Schlagworte: | 3,5-bis[(4-fluoro-3-nitrophenyl)methylene]hexahydro-1-(1-oxo-2-propen-1-yl)-4H-azepin-4-one |
| Anwendung: | 19S proteasomal deubiquitinase inhibitor |
| CAS | 1431280-51-1 |
| MW: | 469.4 D |
ab 54,00 €