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Products from Chimerigen Laboratories
Chimerigen develops and manufactures unique, immunoglobulin-based, chimeric fusion proteins and related research products using advanced cellular and molecular biological techniques. These reagents are used successfully in basic biomedical and applied research.
More information at: www.adipogen.com/chimerigen
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Item number: CHI-HF-210B7H3-C100
The extracellular domain of human CD276 [B7-H3] (aa 29-245) is fused to the N-terminus of the Fc region of human IgG1. CD276 (B7-H3) is a member of the B7/CD28 superfamily of costimulatory molecules serving as an accessory modulator of T cell response. B7 family molecules, which are expressed on antigen-presenting...
Keywords: | B7H3, B7-H3, CD276, PSEC0249, 4Ig-B7-H3, B7 homolog 3, CD276 antigen, Costimulatory molecule |
Application: | Bioassays |
Expressed in: | Hamster cells |
Origin: | human |
429.00€
*
Item number: CHI-HF-22017A-C050
Interleukin-17A (IL-17A) exhibits multiple biological activities on a variety of cells including the induction of IL-6 and IL-8 production in fibroblsts, the enhancement of surface expression of ICAM-1 in fibroblast, activation of NF-kappaB and costimulation of T cell proliferation. Induces stromal cells to produce...
Keywords: | IL-17, IL17A, CTLA8, IL-17A, CTLA-8, Interleukin-17A, Cytotoxic T-lymphocyte-associated antigen 8, Interleukin-17A,... |
Application: | Bioassays |
Expressed in: | Human cells |
Origin: | human |
MW: | ~42 kD |
391.00€
*
Item number: CHI-HF-220BMP2-C050
The extracellular domain of human BMP-2 (aa 289-396) is fused at the C-terminus to the Fc portion of a mutant human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the BMP-2 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Bone...
Keywords: | BMP2, BMP2A, BMP-2, BMP-2A, Bone morphogenetic protein 2, Bone morphogenetic protein 2A |
Application: | Bioassays |
Expressed in: | Hamster cells |
Origin: | human |
484.00€
*
Item number: CHI-MF-110PDL1-C100
Unfortunately, most cytokines have short circulating half-lives. With the creation of a group of new immunoglobulin- based cytokine fusion proteins, in which a cytokine sequence had been genetically fused to the hinge, CH2 and CH3 regions of an immunoglobulin, these cytokine fusion proteins possess both the...
Keywords: | B7h1, B7-H1, Cd274, PD-L1, CD274, B7 homolog 1, PDCD1 ligand 1, Programmed death ligand 1, Programmed cell death 1 ligand 1 |
Application: | Bioassays |
Expressed in: | Hamster cells |
Origin: | mouse |
418.00€
*
Item number: CHI-MF-12004-C010
The extracellular domain of mouse IL-4 (aa 21-140) is fused at the C-terminus to the Fc portion of a mutant mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-4 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Interleukin-4...
Keywords: | Il4, IL-4, BSF-1, Interleukin-4, IGG1 induction factor, B-cell growth factor 1, B-cell stimulatory factor 1, Lymphocyte... |
Application: | Bioassays |
Expressed in: | Mouse cells |
Origin: | mouse |
From 248.00€
*
Item number: CHI-MF-102FGF21-C050
Fibroblast growth factor 21 (FGF-21) is a member of the fibroblast growth factor family and has been identified as an important regulator of energy metabolism connecting nutrition, growth, reproduction and longevity. FGF-21 lacks the heparin-binding domain of most FGF proteins, allowing its secretion. FGF-21 is...
Keywords: | Fgf21, FGF-21, Fibroblast growth factor 21 |
Application: | Bioassays |
Expressed in: | Human cells |
Origin: | mouse |
MW: | ~23 kD |
From 226.00€
*
Item number: CHI-HF-20107-C050
Interleukin-7 (IL-7), is a hematopoietic growth factor and a member of the IL-7/IL-9 family. IL-7 stimulates the proliferation of lymphoid progenitors and is secreted by stromal cells in the bone marrow and thymus. IL-7 is also important for proliferation during certain stages of B cell maturation. IL-7 and the...
Keywords: | IL7, IL-7, Interleukin-7, Interleukin-7, Lymphopoietin 1, LP-1 |
Application: | Bioassays |
Expressed in: | Human cells |
Origin: | human |
MW: | ~27 kD |
From 248.00€
*
Item number: CHI-HF-201CD252-C050
OX40L [CD252, TNFSF4] is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic...
Keywords: | CD252, Ox40l, OX40L, Tnfsf4, OX40 ligand, Tumor necrosis factor ligand superfamily member 4, TNFSF4 |
Application: | Bioassays |
Expressed in: | Human cells |
Origin: | human |
MW: | ~27 kD |
391.00€
*
Item number: CHI-HF-21006-C050
The extracellular domain of human IL-6 (aa 30-212) is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin 6 (IL-6) is a pleiotropic alphahelical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone...
Keywords: | CDF, IL6, IL-6, BSF-2, IFNB2, IFN-beta-2, Interleukin-6, Interferon beta-2, Hybridoma growth factor, CTL differentiation... |
Application: | Bioassays |
Expressed in: | Hamster cells |
Origin: | human |
209.00€
*
Item number: CHI-HF-21006R-C050
The extracellular domain of human IL-6R (aa 20-359) is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-6 (IL-6) is a multifunctional factor, which exerts its activities through binding to a highaffinity receptor complex consisting of two membrane...
Keywords: | gp80, IL6R, CD126, IL-6RA, IL-6R 1, IL-6R-alpha, IL-6R subunit alpha, Membrane glycoprotein 80, IL-6 receptor subunit... |
Application: | Bioassays |
Expressed in: | Hamster cells |
Origin: | human |
369.00€
*
Item number: CHI-HF-210CD160-C100
CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim) CD16(+) peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 acts as a co-activator receptor for...
Keywords: | BY55, CD160, CD160 antigen, Natural killer cell receptor BY55, Natural Killer Cell Receptor BY55, NK28, NK1 |
Application: | Bioassays |
Expressed in: | Hamster cells |
Origin: | human |
429.00€
*
Item number: CHI-HF-210CD38-C100
CD38, also known as cyclic ADP ribose hydrolase is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells. CD38 also functions in cell adhesion, signal transduction and calcium signaling.CD38 is a multifunctional ectoenzyme that...
Keywords: | T10, CD38, ADPRC 1, EC=3.2.2.6, EC=2.4.99.20, cADPr hydrolase 1, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1,... |
Application: | Bioassays |
Expressed in: | Human cells |
Origin: | human |
MW: | ~70 kD |
429.00€
*