Products from Chemodex
Chemodex Ltd. from Switzerland (founded in 2001 in St. Gallen) are experts in the synthesis of fluorescent substances derived from fluorophores such as coumarin, fluorescein, rhodamine and pyrene. The reagents are used as probes, stains, markers, NIR-labels, pH-sensors, ion indicators, chelators and in other applications (e.g. analytical biochemistry, immunoassays and microscopy). The various products are used by natural science researchers in academia, biotechnology and the pharmaceutical industry.
More information at: www.adipogen.com/chemodex
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1-Pyrenebutanoic acid hydrazide
Item number: CDX-P0049-G001
1-Pyrenebutanoic acid hydrazide (PBH) is a fluorescent labeling reagent commonly used in biochemistry and molecular biology. Spectral Data: lambdaex 340nm, lambdaem 375nm (MeOH). The hydrazide group reacts with carbonyl groups (like aldehydes or ketones) to form hydrazones. This makes PBH useful for labeling...
| Keywords: | PBH, 1-Pyrenebutyric hydrazide, Pyrenebutyrylhydrazine |
| Application: | Fluorescent labeling reagent, oxidized sugar/glycoprotein/carbonylated biomolecule labeling |
| MW: | 302.37 D |
From 240.00€
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Phenmedipham-ethyl
Item number: CDX-P0589-M025
Phenmedipham-ethyl is an impurity of phenmedipham which is a carbanilate selective herbicide used post-emergence in beet crops after the emergence of most broad-leaved weeds and before they develop. Phenmedipham inhibits photosynthesis (photosystem II) and acts by disrupting carbon dioxide. This compound can be used...
| Keywords: | 3-Ethoxycarbonylaminophenyl 3-methylcarbanilate |
| Application: | Analytical reference material, impurity |
| MW: | 314.34 D |
117.00€
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Pioglitazone hydrochloride
Item number: CDX-P0733-M010
Pioglitazone hydrochloride is a proliferator-activated receptor gamma (PPARgamma) agonist (EC50 = ~500-600nM for both human and murine PPARgamma) and thiazolidinedione (TZD) anti-diabetic. Pioglitazone is a selective agonist of the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-gamma) and to...
| Keywords: | 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione monohydrochloride, U 72107A |
| Application: | PPARgamma agonist |
| MW: | 392.9 D |
From 65.00€
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mono-Methyl phthalate
Item number: CDX-P0739-G025
Mono-methyl phthalate (MMP) is a phthalate metabolite. MMP is studied as a biodegradation product of dimethyl phthalate (DMP), a common plasticizer. It serves as an indicator of phthalate pollution and microbial degradation activity. MMP is a metabolite found in biological fluids (e.g. urine) following exposure to...
| Keywords: | MMP, Monomethyl phthalate, o-(Methoxycarbonyl)benzoic acid, Methyl 2-carboxybenzoate, 2-(1-Methoxycarbonyl)benzoic acid,... |
| Application: | Phthalate metabolite, reference compound, LC-MS, GC-MS |
| MW: | 180.16 D |
123.00€
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Rhodamine B hydrazide
Item number: CDX-R0178-M050
Rhodamine B hydrazide is a water-soluble fluorescent probe. Rhodamine B hydrazide can be used to label biomolecules (e.g. proteins, sugars) that have aldehyde or ketone groups. Spectral Data: lambdaex 510nm, lambdaem 578nm. It has been used for the detection of copper, peroxynitrite, nitric oxide, hydrogen peroxide,...
| Keywords: | 2-Amino-3',6'-bis(diethylamino)-spiro[1H-isoindole-1,9'-[9H]xanthen]-3(2H)-one |
| Application: | Water-soluble fluorescent probe, aldehyde / ketone group labeling |
| MW: | 456.59 D |
From 246.00€
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Sarcosine
Item number: CDX-S0121-G025
Sarcosine (N-methylglycine) is a naturally occurring amino acid derivative that plays an important role as an intermediate in glycine and choline metabolism. It functions as a modulator of N-methyl-D-aspartate (NMDA) receptor activity a selective inhibitor of glycine transporter 1 (GlyT1), thereby enhancing synaptic...
| Keywords: | N-Methylglycine, H-NMeGly-OH, 2-(Methylamino)acetic acid |
| Application: | Naturally occurring amino acid derivative, NMDA receptor modulator, GlyT1 inhibitor |
| MW: | 89.09 D |
From 58.00€
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Sorafenib tosylate
Item number: CDX-S0264-G005
Sorafenib tysolate is a multi-kinase inhibitor that inhibits Raf-1 and B-RAF (IC50s = 6n and 22nM, respectively), as well as the receptor tyrosine kinases VEGFR2, VEGFR3, PDGFRbeta, Flt-3, c-Kit, FGFR-1 (Flt-2) and RET, involved in neovascularization and tumor progression. It is selective for these kinases over 12...
| Keywords: | Sorafenib p-toluenesulfonate, Nexavar, ,BAY 43-9006 mono-p-tosylate, BAY 54-9085 |
| Application: | Kinase inhibitor |
| MW: | 637.03 D |
From 87.00€
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Sunitinib malate
Item number: CDX-S0330-G001
Sunitinib malate is a potent ATP-competitive and cell permeable multi-targeted receptor tyrosine kinase (RTK) inhibitor targeting VEGFR, PDGFR-beta and c-Kit (Ki = 2-17nM). It inhibits FLK1 (Ki=9nM), PDGFRbeta (Ki=8nM) and FLT3. It is at least 10-fold selective for FLK1 and PDGFRbeta over a variety of tyrosine...
| Keywords: | Sunitinib L-malate, SU112248,... |
| Application: | Antineoplastic, angiogenesis inhibitor, receptor tyrosine kinase inhibitor |
| MW: | 532.56 D |
305.00€
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Sanguinarine chloride hydrate
Item number: CDX-S0377-M010
Sanguinarine chloride is a quaternary ammonium benzophenanthine alkaloid found in traditional herbs such as Chelidonium, Corydalis, Sanguinarum, and Borovula. It has been proven to possess broad-spectrum biological activities, such as antitumor, anti-inflammatory, antiosteoporosis, neuroprotective, immune...
| Keywords: | Sanguinarine hydrochloride |
| Application: | Bioactive alkaloid |
| MW: | 367.78(ah) D |
From 189.00€
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Tetramethylrhodamine methyl ester perchlorate
Item number: CDX-T0012-M025
Tetramethylrhodamine methyl ester perchlorate (TMRM) is a cell-permeant, cationic fluorescent dye widely used to assess mitochondrial membrane potential and for labeling mitochondria in live-cell imaging and flow cytometry. By selectively accumulating in active mitochondria according to their membrane potential,...
| Keywords: | TMRM, TMR methyl ester |
| Application: | Cell-permeant, cationic fluorescent dye, mitochondria labeling mitochondria, live-cell imaging, FC |
| MW: | 500.93 D |
From 204.00€
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Tetramethylrhodamine ethyl ester perchlorate
Item number: CDX-T0057-M025
Tetramethylrhodamine ethyl ester perchlorate (TMRE) is a cell-permeant, cationic fluorescent dye widely used to assess mitochondrial membrane potential and for labeling mitochondria in live-cell imaging and flow cytometry. By selectively accumulating in active mitochondria according to their membrane potential, TMRE...
| Keywords: | TMRE, TMR ethyl ester, T 669 |
| Application: | Cell-permeant, cationic fluorescent dye, mitochondria labeling mitochondria, live-cell imaging, FC |
| MW: | 514.95 D |
138.00€
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Trazodone hydrochloride
Item number: CDX-T0476-G001
Trazodone hydrochloride belongs to the class of serotonin receptor antagonists and reuptake inhibitors (SARIs). Trazodone hydrochloride has anti-depressant and neuroprotectant activity. Trazodone hydrochloride exerts antagonistic properties against alpha1- and alpha2-adrenergic receptors and histamine H1 receptors,...
| Keywords: | 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one hydrochloride, AF 1161, Desyrel,... |
| Application: | Serotonin antagonist and reuptake inhibitor (SARI) |
| MW: | 408.32 D |
From 51.00€
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