Sorafenib tosylate
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| CDX-S0264-G005 | 5 g | - | - |
3 - 9 business days* |
87.00€
|
||
| CDX-S0264-G025 | 25 g | - | - |
3 - 9 business days* |
349.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Sorafenib tysolate is a multi-kinase inhibitor that inhibits Raf-1 and B-RAF (IC50s = 6n and... more
Product information "Sorafenib tosylate"
Sorafenib tysolate is a multi-kinase inhibitor that inhibits Raf-1 and B-RAF (IC50s = 6n and 22nM, respectively), as well as the receptor tyrosine kinases VEGFR2, VEGFR3, PDGFRbeta, Flt-3, c-Kit, FGFR-1 (Flt-2) and RET, involved in neovascularization and tumor progression. It is selective for these kinases over 12 other kinases, including ERK1, MEK1, EGFR, and HER2 (IC50s = >10µM for all). Sorafenib tosylate exerts broad-spectrum anticancer activity and disrupts signaling pathways that are vital for tumor growth and angiogenesis.
| Keywords: | Sorafenib p-toluenesulfonate, Nexavar, ,BAY 43-9006 mono-p-tosylate, BAY 54-9085 |
| Supplier: | Chemodex |
| Supplier-Nr: | S0264 |
Properties
| Application: | Kinase inhibitor |
| MW: | 637.03 D |
| Formula: | C21H16ClF3N4O3 . C7H8SO3 |
| Format: | Solid |
Database Information
| KEGG ID : | K04366 | Matching products |
Handling & Safety
| Storage: | +4°C (protect from light & moisture) |
| Shipping: | +20°C (International: +20°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H360FD, H362, H372, H410 |
| P Phrases: | P202, P260, P263, P264, P273, P308+P313 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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