Products from Bethyl

Bethyl

Bethyl is based in Montgomery, Texas, USA. Bethyl's mission is to be the premier provider of polyclonal antibodies to the research market. Bethyl will do this by continuous identfication of new and emerging proteins of interest through collaborations and scholarly searches. Bethyl is unique in their end-to-end control of the entire antibody lifecycle. From the veterinary facilities to the development, production and validation labs, the Bethyl team focuses on delivering quality products. This attention to quality at every step and the integration across each stage of the process means scientists can rely on Bethyl antibodies.

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Anti-ADNP (IHC)
Anti-ADNP (IHC)

Item number: IHC-00118-T

Protein function: Potential transcription factor. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation. [The UniProt Consortium]
Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-MSH6 (IHC)
Anti-MSH6 (IHC)

Item number: IHC-00119-T

Protein function: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA....
Application: IHC
Antibody Type: Polyclonal
Host: Goat
Reactivity: Human
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-BID (IHC)
Anti-BID (IHC)

Item number: IHC-00121-T

Protein function: The major proteolytic product p15 BID allows the release of cytochrome c. Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2. [The UniProt Consortium]
Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-BHC110/LSD1 (IHC)
Anti-BHC110/LSD1 (IHC)

Item number: IHC-00122-T

Protein function: Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for...
Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-Bub3 (IHC)
Anti-Bub3 (IHC)

Item number: IHC-00123-T

Protein function: Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the...
Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-BIRC6/Apollon (IHC)
Anti-BIRC6/Apollon (IHC)

Item number: IHC-00124-T

Protein function: Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and...
Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-AF9 (IHC)
Anti-AF9 (IHC)

Item number: IHC-00125-T

Protein function: Component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. [The UniProt Consortium]
Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-CDX2 (IHC)
Anti-CDX2 (IHC)

Item number: IHC-00126-T

Protein function: Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. [The UniProt Consortium]
Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-4E-T(eIF4E-T) (IHC)
Anti-4E-T(eIF4E-T) (IHC)

Item number: IHC-00127-T

Protein function: Nucleoplasmic shuttling protein. Mediates the nuclear import of EIF4E by a piggy-back mechanism. [The UniProt Consortium]
Application: IHC, IHC-IF
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-CDT1 (IHC)
Anti-CDT1 (IHC)

Item number: IHC-00128-T

Protein function: Cooperates with CDC6 to promote the loading of the mini- chromosome maintenance complex onto chromatin to form the pre- replication complex necessary to initiate DNA replication. Binds DNA in a sequence-, strand-, and conformation-independent manner. Potential oncogene. [The UniProt Consortium]
Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-BAF57/SMARCE1 (IHC)
Anti-BAF57/SMARCE1 (IHC)

Item number: IHC-00129-T

Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a...
Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse
Format: Antigen Affinity Purified
From 125.00€
Review
Anti-CBX5 (IHC)
Anti-CBX5 (IHC)

Item number: IHC-00130-T

Protein function: Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with...
Application: IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Format: Antigen Affinity Purified
From 125.00€
Review
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