19 products were found matching "T2182"!
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Nav1.7-IN-2
Item number: TGM-T12182-50mg
Description: Nav1.7-IN-2 is avoltage-gated sodium channels (Nav) inhibitor in particular Nav 1.7(IC50 of 80 nM). Target: Others. Smiles: CNC(=O)c1cccc(Nc2nccc(n2)N2CC(C2)Oc2ccc(F)cc2C)c1. References: Bregman Howard, et al. Preparation of aryl carboxamide derivatives as sodium channel inhibitors for treatment of...
| MW: | 407.44 D |
From 339.00€
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LT175
Item number: TGM-T21812-1mg
Description: LT175, a dual PPARalpha/gamma ligand, demonstrates potent insulin-sensitizing effects with reduced adipogenic properties. This orally active partial agonist targets PPARgamma with EC50 values of 0.22 µm for hPPARalpha, 0.26 µm for mPPARalpha, and 0.48 µm for hPPARgamma. LT175 specifically interacts with...
| MW: | 318.37 D |
77.00€
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2-fluoro Palmitic Acid
Item number: TGM-T21842-25mg
Description: 2-Fluoropalmitic acid, functioning as an acyl-CoA synthetase inhibitor, is a potential anti-glioma agent. It diminishes the viability and stem-like characteristics of glioma stem cells (GSCs) and hinders the proliferation and invasion of glioma cell lines [1]. Target: Others. Smiles: CCCCCCCCCC...
| MW: | 274.41 D |
613.00€
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AEG 3482
Item number: TGM-T21852-1mg
Description: AEG 3482 is a potent antiapoptotic compound. AEG 3482 inhibits Jun kinase (JNK) activity through induced expression of heat shock protein 70 (HSP70). AEG 3482 directly binds HSP90, thereby facilitating HSF1-dependent expression of HSP70 and HSP25. Target: Apoptosis. Smiles:...
| MW: | 280.33 D |
34.00€
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CCT018159
Item number: TGM-T21872-1mg
Description: CCT018159 is a 3,4-diarylpyrazole resorcinol, an ATP-competitive HSP90ATPase inhibitor that inhibits human Hsp90beta and yeast Hsp90 with IC50s of 3.2 and 6.6 µM, respectively.CCT018159 inhibits key endothelial and tumor cell functions associated with invasion and angiogenesis. CCT018159 caused cellular...
| MW: | 352.38 D |
32.00€
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Iopydone
Item number: TGM-T32182-500mg
Description: Iopydone is an iodinated contrast dye. Smiles: O=C1C(I)=CNC=C1I. References: Watanabe A, Saka H, Hasegawa Y, Shimokata K. [Survey of the state of bronchography in Japan]. Nihon Kyobu Shikkan Gakkai Zasshi. 1995 Feb,33(2):127-31. Japanese. PubMed PMID: 7731115.
| Keywords: | NSC-135284, Iopydonum, Hytrast, NSC 135284, NSC135284 |
| MW: | 346.89 D |
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NIC-0102
Item number: TGM-T62182-100mg
Description: NIC-0102 is an orally active proteasome inhibitor (pIC50: 7.55) that specifically inhibits NLRP3 inflammatory vesicle activation. Target: Others. Smiles: C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)B(O)O)=O)(=O)C2=C(F)C=CC=C2F
| MW: | 418.24 D |
From 1,491.00€
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Combretastatin A1 phosphate
Item number: TGM-T72182-50mg
Description: Combretastatin A1 phosphate, a potent vascular disruptive agent, exhibits anti-angiogenic effects on tumors and holds potential for research on pancreatic neuroendocrine tumors. Target: Others. Smiles: O(P(=O)(O)O)C1=C(OP(=O)(O)O)C(OC)=CC=C1/C=C\C2=CC(OC)=C(OC)C(OC)=C2
| Keywords: | Oxi4503 , CA1P , Combretastatin A1 diphosphate, Combretastatin A1 diphosphate, Oxi4503 , CA1P , Combretastatin A1... |
| MW: | 492.31 D |
From 2,227.00€
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Hosenkoside L
Item number: TGM-T82182-50mg
Description: Hosenkoside L, a baccharane-type glycoside, is characterized by specific functional groups attached to a baccharane skeleton [1]. Smiles:...
| MW: | 949.13 D |
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Sarracenin
Item number: TGM-TN2182-10mg
Description: Sarracenin is a natural product. Sarracenin shows cytotoxic activities against tumor cells. Target: Others. Smiles: [H][C@]12C[C@]3([H])C(=CO[C@]([H])(O1)[C@]3([H])[C@H](C)O2)C(=O)OC. References: Iridoid Glucosides from Chinese Herb Lonicera chrysatha and Their Antitumor Activity.Journal of Chemical...
| MW: | 226.23 D |
From 63.00€
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Lamin fragment
Item number: TGM-TP2182-10mg
Description: Lamin fragment has a peptide sequence of Lys-Ala-Gly-Gln-Val-Val-Thr-Ile-Trp. Lamin polypeptides have an almost complete alpha-helical conformation with multiple alpha-helical domains separated by non-alpha-helical linkers that are highly conserved in length and amino acid sequence. Nuclear lamins are...
| MW: | 1001.18 D |
From 50.00€
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Resistomycin
Item number: TGM-T21820-1mg
Description: Resistomycin (Geliomycin), a pentacyclic polyketide antibiotic, exhibits potent anticancer properties by triggering apoptosis. Target: Antibiotic. Smiles: Cc1cc(O)c2C(=O)c3c(O)cc(O)c4C(=O)C(C)(C)c5cc(O)c1c2c5-c34. References: Liu SS, et al. Resistomycin attenuates triple-negative breast cancer...
| Keywords: | Geliomycin, Heliomycin |
| MW: | 376.36 D |
177.00€
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