- Search results for 5991-1
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10 products were found matching "5991-1"!
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Item number: Cay28926-1
AZD 5991 is an inhibitor of myeloid cell leukemia-1 (Mcl-1, IC50 = 0.72 nM). It is selective for Mcl-1 over Bcl-2, Bcl-xL, Bcl-W, and Bfl-1 (IC50s = 20, 36, 49, and 24 µM, respectively). AZD 5991 decreases the viability of MV4-11 acute myeloid leukemia (AML) and MOLP-8 multiple myeloma (MM) cells with EC50 values of...
Keywords: | (3aR)-5-chloro-2,11,12,24,27,29-hexahydro-2,3,24,33-tetramethyl-22H-9,4,8-(metheniminomethyno)-14,20:26,23-dimetheno-10H,2... |
Application: | Mcl-1 inhibitor |
CAS | 2143061-81-6 |
MW: | 672.3 D |
From 130.00€
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Item number: E-AB-15991.120
Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the...
Keywords: | Anti-MYSM1, Anti-2A-DUB, Anti-KIAA1915, EC=3.4.19.-, Anti-Histone H2A deubiquitinase MYSM1, Anti-Myb-like, SWIRM and MPN... |
Application: | WB, IHC, ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 71.00€
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Item number: Cay15991-50
Dibutyryl-cyclic GMP (dibutyryl-cGMP) is a cell-permeable, cGMP analog that activates cGMP-dependent protein kinase. It has been used in a wide variety of research applications to mimic cGMP interactions and effects on different biological molecules.Formal Name: N-(1-oxobutyl)-cyclic 3',5'-(hydrogen phosphate)...
Keywords: | Dibutyryl Guanosine 3',5'-cyclic monophosphate, Dibutyryl-cGMP, N-(1-oxobutyl)-cyclic 3',5'-(hydrogen phosphate)... |
Application: | Cell-permeable cGMP analog, cGMP-dependent protein kinase activator |
CAS | 51116-00-8 |
MW: | 507.4 D |
From 90.00€
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Item number: Cay25991-1
DBO-83 is an agonist of nicotinic acetylcholine receptors (nAChRs) with antinociceptive and anti-amnesic activities. It binds to nAChRs in rat cortical membranes with a Ki value of 4.1 nM in a radioligand binding assay with the alpha4beta2 nAChR partial agonist and alpha7 nAChR agonist [3H]cytisine. DBO-83...
Keywords: | 3-(6-chloro-3-pyridazinyl)-3,8-diazabicyclo[3.2.1]octane, dihydrochloride |
Application: | nAChR agonist |
CAS | 195211-53-1 |
MW: | 297.6 D |
From 50.00€
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Item number: VHPS-5991
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Keywords: | MYL4, MLC1, PRO1957, Myosin light chain 4, Myosin light chain alkali GT-1 isoform, Myosin light chain 1, embryonic... |
Application: | RNA quantification |
43.00€
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Item number: VRPS-5991
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Keywords: | S5AR 2, Srd5a2, SR type 2, EC=1.3.99.5, 5 alpha-SR2, Steroid 5-alpha-reductase 2, 3-oxo-5-alpha-steroid 4-dehydrogenase 2 |
Application: | RNA quantification |
52.00€
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Item number: ELK-ES5991.100
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth...
Keywords: | Anti-phospho-DRK1, Anti-phospho-h-DRK1, Anti-phospho-Delayed rectifier potassium channel 1, Anti-phospho-Voltage-gated... |
Application: | WB, ELISA, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 169.00€
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Item number: 145991.100
TGF-beta and the bone morphogenic proteins (BMPs) are key signaling proteins that regulate numerous cellular processes such as embryonic development and tumorigenesis. Both signal through the Smad protein family and are negatively regulated by Ski and SnoN, two related proto-oncoproteins. Ski functions by binding to...
Application: | ELISA, IF, WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
644.00€
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Item number: E-AB-52991.120
In acute myeloid leukemia, especially in the M2 subtype, the t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is...
Keywords: | Anti-EHT, Anti-p85, Anti-CBFA2T2, Anti-Protein CBFA2T2, Anti-MTG8-like protein, Anti-MTG8-related protein 1, Anti-ETO... |
Application: | IHC, ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 71.00€
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Item number: 155991.10
Accession Number: P05976/
From 399.00€
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