Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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SLC4011540
Item number: TGM-T28801-25mg
Description: SLC4011540 is a potent and selective SphK1/2 dual inhibitor with Ki value of 120 nM and 90 nM respectively. Target: Others. Smiles: [NH2+]=C(N)N1[C@H](CC2=NC(C3=CC=C(NC4=NC(C5=CC=CC(C(F)(F)F)=C5)=CS4)C=C3)=NO2)CCC1.[Cl-]
| Keywords: | SLC-4011540 , SLC 4011540 |
| MW: | 550 D |
From 1,867.00€
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Crustecdysone
Item number: TGM-T2881-100mg
Description: Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects. Target: Endogenous Metabolite, Autophagy, Caspase. Smiles: CC(C)(O)CCC(O)C(C)(O)C1CCC2(O)C3=CC(=O)C4CC(O)C(O)CC4(C)C3CCC12C
| Keywords: | 20-Hydroxyecdysone , Commisterone , Ecdysterone , B-ecdysone , Hydroxyecdysone |
| MW: | 480.63 D |
From 31.00€
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SPM-242
Item number: TGM-T28838-25mg
Description: SPM-242 is an orthosteric agonist of Sphingosine 1-phosphate (S1P) and a bitopic antagonist. S1P is a lysophospholipid signaling molecule that regulates important biological functions, including vascular development and lymphocyte trafficking, by activating G protein-coupled receptors for S1P, namely,...
| Keywords: | SPM 242 |
| MW: | 419.81 D |
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SU 10603
Item number: TGM-T28871-100mg
Description: SU 10603 is a specific inhibitor of 17alpha-hydroxylase (also known as CYP17A1 and P450c17) used to study steroid hormone synthesis. Target: Hydroxylase, Cytochromes P450. Smiles: Clc1ccc2CCC(C(=O)c2c1)c1cccnc1
| Keywords: | SU-10603 , SU10603 |
| MW: | 257.72 D |
From 276.00€
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Tesofensine
Item number: TGM-T28951-10mg
Description: Tesofensine, a serotoninâ?"noradrenalineâ?"dopamine reuptake inhibitor, is used potentially for the treatment of obesity. Target: Serotonin Transporter, Dopamine Receptor, Others. Smiles: [H][C@]12CC[C@]([H])([C@H](COCC)[C@H](C1)c1ccc(Cl)c(Cl)c1)N2C
| Keywords: | NS 2330 , NS2330 , NS-2330 |
| MW: | 328.28 D |
850.00€
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TRC-19
Item number: TGM-T29003-25mg
Description: TRC-19 is a potent and selective inhibitor of Toxoplasma gondii dihydrofolate reductase. TRC-19 shows an IC50 of 9 nM and 89-fold selectivity in favor of Toxoplasma gondii dihydrofolate reductase. Target: Others. Smiles: NC1=C(N2CCN(C3=CC(C4=CC=CC=C4)=CC=C3)CC2)C=NC(N)=N1
| MW: | 346.44 D |
From 1,440.00€
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UK-414,495
Item number: TGM-T29052-25mg
Description: UK-414,495 is a potent, selective inhibitor of the neutral endopeptidase, the enzyme normally serves to break down the neuropeptide VIP. Target: Neprilysin, Others. Smiles: CCCC(CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O
| Keywords: | UK 414495 , UK414,495 , UK414495 , UK-414495 |
| MW: | 339.45 D |
From 1,440.00€
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UNC3133
Item number: TGM-T29062-25mg
Description: UNC3133 is a potent and selective Mer tyrosine kinase (MerTK) inhibitor with IC50 Mer 3.0 nM, Axl 17nM, Tyro 3.31 nM, FLT3 6.6 nM, PO Cmax = 0.023, IV T1/2 = 1.59 h, %F = 16. Mer tyrosine kinase (MerTK) is aberrantly elevated in various tumor cells and has a normal anti-inflammatory role in the innate...
| Keywords: | UNC 3133 , UNC-3133 |
| MW: | 504.72 D |
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V-11-0711 HCl
Item number: TGM-T29083L-10mg
Description: V-11-0711 HCl is a selective and highly effective choline kinase alpha (ChoKalpha) inhibitor that inhibits the catalytic activity of Chk. Target: AChR. Smiles: O[C@@]([C@]1([H])C2CCN(CC2)C1)(C3=CC=CC=C3)CCC4=C(C=CC=C4)OC5CCOCC5.Cl
| Keywords: | V-11-0711 HCl(1428339-47-2 Free base) |
| MW: | 458.03 D |
From 200.00€
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XIE18-6
Item number: TGM-T29166-10mg
Description: XIE18-6 is a novel INK4C inhibitor that selectively blocks the biological activity of the p18 protein, a regulator of the cell cycle. XIE18-6 promotes the ex vivo expansion of both human and murine hematopoietic stem cells, making it a valuable tool for stem cell biology and regenerative medicine...
| Keywords: | XIE186 |
| MW: | 373.38 D |
From 29.00€
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(-)-Inpea HCl
Item number: TGM-T29239-25mg
Description: (-)-Inpea HCl is a bioactive chemical. Target: Others. Smiles: [C@@H](CNC(C)C)(O)C1=CC=C(N(=O)=O)C=C1.Cl
| Keywords: | (-)-Inpea hydrochloride , l-Inpea hydrochloride |
| MW: | 260.72 D |
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(+)-Armepavine
Item number: TGM-T29243-25mg
Description: (+)-Armepavine is a bioactive chemical. Target: Others. Smiles: C([C@H]1C=2C(=CC(OC)=C(OC)C2)CCN1C)C3=CC=C(O)C=C3
| Keywords: | L-(+)-Armepavine , S-(+)-Armepavine , (S)-Armepavine |
| MW: | 313.39 D |
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