UNC3133

UNC3133
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T29062-25mg 25 mg - - -

7 - 10 business days*

-
TGM-T29062-50mg 50 mg - - -

7 - 10 business days*

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Description: UNC3133 is a potent and selective Mer tyrosine kinase (MerTK) inhibitor with IC50... more
Product information "UNC3133"
Description: UNC3133 is a potent and selective Mer tyrosine kinase (MerTK) inhibitor with IC50 Mer 3.0 nM, Axl 17nM, Tyro 3.31 nM, FLT3 6.6 nM, PO Cmax = 0.023, IV T1/2 = 1.59 h, %F = 16. Mer tyrosine kinase (MerTK) is aberrantly elevated in various tumor cells and has a normal anti-inflammatory role in the innate immune system. Inhibition of MerTK may provide dual effects against these MerTK-expressing tumors through reducing cancer cell survival and redirecting the innate immune response. Target: Others. Smiles: OC(CCCC1)CCCCCCCNC2=NC=C3C(N1C=C3C4=CC=C(CN5CCN(C)CC5)C=C4)=N2
Keywords: UNC 3133 , UNC-3133
Supplier: TargetMol
Supplier-Nr: T29062

Properties

MW: 504.72 D
Formula: C30H44N6O

Database Information

Handling & Safety

Storage: +4°C
Shipping: +20°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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