Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Fulvestrant
Item number: TGM-T2146-10mg
Description: Fulvestrant (ZM 182780) is an estrogen receptor (ER) antagonist (IC50=9.4 nM) and an agonist of GPR30. Fulvestrant has antitumor activity, inhibiting cell proliferation and inducing apoptosis and autophagy. Target: Autophagy, Estrogen/progestogen Receptor, Estrogen Receptor/ERR, Apoptosis. Smiles:...
| Keywords: | ZM 182780, ZD 9238, ICI 182780 |
| CAS | 129453-61-8 |
| MW: | 606.77 D |
From 40.00€
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Cell Counting Kit-8 (CCK-8)
Item number: TGM-C0005-1mL
Description: Cell Counting Kit-8 (CCK-8) allows very convenient assays by utilizing the highly water-soluble tetrazolium salt WST-8 [2-(2-methoxy-4-nitrophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium,monosodium salt] produces a water-soluble formazan dye upon reduction in the presence of an electron...
| Keywords: | CCK8, CCK 8 |
From 20.00€
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Permethrin
Item number: TGM-T1332-100mg
Description: Permethrin (NRDC-143) is a pyrethroid insecticide commonly used in the treatment of LICE INFESTATIO NS and SCABIES. Target: Sodium Channel, Parasite. Smiles: CC1(C)[C@@H](C=C(Cl)Cl)C1C(=O)OCc1cccc(Oc2ccccc2)c1. References: Cao Z, et al. J Pharmacol Exp Ther. 2011, 336(1):197-205.
| Keywords: | Transpermethrin, Pounce, Ambush, NRDC-143 |
| Application: | Insecticide, Ectoparasiticide |
| CAS | 52645-53-1 |
| MW: | 391.29 D |
From 29.00€
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Bucladesine sodium
Item number: TGM-T1418-2g
Description: Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties. Bucladesine sodium is also a cAMP-dependent protein kinase (PKA) activator and a phosphodiester (PDE) inhibitor. Bucladesine sodium has anti-inflammatory activity. Target: PDE, PKA. Smiles:...
| Keywords: | Sodium dibutyryl cAMP, Bucladesine, Bucladesine sodium salt, Dibutyryl-cAMP, DC2797, Dibutyryl-cAMP sodium salt, dbcAMP |
| Application: | Antiulcerative (skin), Cardiotonic, Phosphodiesterase inhibitor |
| CAS | 16980-89-5 |
| MW: | 491.37 D |
From 30.00€
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Dynarrestin
Item number: TGM-T15183-2mg
Description: Dynarrestin is a cytoplasmic dynein 1 and 2 aminothiazole inhibitor that reversibly inhibits dynein 1-driven microtubule sliding in vitro and intracellular dynein 1 and 2-dependent processes without affecting ATP hydrolysis and interfering with ciliogenesis . Target: Hedgehog/Smoothened. Smiles:...
| Application: | Dynein inhibitor |
| CAS | 2222768-84-3 |
| MW: | 431.5 D |
From 53.00€
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Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO)
Item number: TGM-C0001-1mL
Description: TargetMol provides a wide array of customizable Protease Inhibitor Cocktails, each with varying mechanisms of actions, aimed at protecting your protein samples. They work by helping proteins avoid rapid degradation caused by endogenous proteases during the cell lysis and protein purification processes....
27.00€
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BI-847325
Item number: TGM-T6785-5mg
Description: BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively. Target: MEK, Aurora Kinase, Apoptosis. Smiles: CCNC(=O)C#Cc1ccc2\C(=C(\Nc3ccc(CN(C)C)cc3)c3ccccc3)C(=O)Nc2c1. References: Phadke MS, et al. Mol Cancer Ther....
| Application: | MEK / Aurora kinase inhibitor |
| CAS | 1207293-36-4 |
| MW: | 464.56 D |
From 40.00€
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Vancomycin hydrochloride
Item number: TGM-T0832-1g
Description: Vancomycin hydrochloride (Vancomycin HCl) is the hydrochloride salt of vancomycin, a branched tricyclic glycosylated peptide with bactericidal activity against most organisms and bacteriostatic effect on enterococci. Target: Autophagy, Antibacterial, Antibiotic, Cell wall. Smiles:...
| Keywords: | Vancomycin HCl |
| CAS | 1404-93-9 |
| MW: | 1485.71 D |
51.00€
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Sunitinib Malate
Item number: TGM-T0374-50mg
Description: Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor. It blocks the tyrosine kinase activities of VEGFR2, PDGFRbeta (IC50: 80/2 nM), and c-kit. Target: VEGFR, c-Kit, Autophagy, FLT, PDGFR, IRE1, Apoptosis, Mitophagy. Smiles:...
| Keywords: | SU 11248 (Malate), Sutent, SU 11248, Sunitinib |
| CAS | 341031-54-7 |
| MW: | 532.56 D |
From 36.00€
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SC-514
Item number: TGM-T2118-5mg
Description: SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 µM), obstructs NF-kappaB-dependent gene expression. Target: IkappaB/IKK, p38 MAPK, CDK, Aurora Kinase, Serine Protease. Smiles: NC(=O)c1sc(cc1N)-c1ccsc1. References: Kishore N, et al. J Biol Chem, 2003,...
| Keywords: | GK 01140 |
| Application: | IKK2 inhibitor |
| CAS | 354812-17-2 |
| MW: | 224.3 D |
From 30.00€
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Resiniferatoxin
Item number: TGM-T34295-1mg
Description: Resiniferatoxin ((+)-Resiniferatoxin) is a highly potent synthetic TRPV1 agonist that inhibits the production of Th1 cytokines and has anti-inflammatory activity, reducing serum levels of IL-12, INF-gamma, IL-1beta, TNF-alpha, NO, and PGE. Target: TRP/TRPV Channel, IL Receptor. Smiles:...
| Keywords: | RTX , [3H]resiniferatoxin |
| Application: | Highly potent TRPV1 agonist |
| CAS | 57444-62-9 |
| MW: | 628.71 D |
From 431.00€
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SC-26196
Item number: TGM-T12856-5mg
Description: SC-26196 is an orally active inhibitor of Delta6 desaturase (D6D) with IC50 of 0.2 µM in a rat liver microsomal assay, with antiinflammatory properties. Target: Others. Smiles: N#CC(CCCN1CCN(CC1)\N=C\c1cccnc1)(c1ccccc1)c1ccccc1. References: Sibbons CM, et al. Polyunsaturated Fatty Acid Biosynthesis...
| Application: | Delta6 desaturase inhibitor |
| CAS | 218136-59-5 |
| MW: | 423.55 D |
From 30.00€
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