Sunitinib Malate
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor. It... more
Product information "Sunitinib Malate"
Description: Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor. It blocks the tyrosine kinase activities of VEGFR2, PDGFRbeta (IC50: 80/2 nM), and c-kit. Target: VEGFR, c-Kit, Autophagy, FLT, PDGFR, IRE1, Apoptosis, Mitophagy. Smiles: O[C@@H](CC(O)=O)C(O)=O.CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C. References: Sun L, et al. Discovery of 5-[5-fluoro-2-oxo-1,2- dihydroindol-(3Z)-ylidenemethyl]-2,4- dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide, a novel tyrosine kinase inhibitor targeting vascular endothelial and platelet-derived growth factor receptor tyrosine kinase. J Med Chem. 2003 Mar 27,46(7):1116-9.
| Keywords: | SU 11248 (Malate), Sutent, SU 11248, Sunitinib |
| Supplier: | TargetMol |
| Supplier-Nr: | T0374 |
Properties
| MW: | 532.56 D |
| Formula: | C26H33FN4O7 |
Database Information
| CAS : | 341031-54-7| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H360, H372 |
| P Phrases: | P201, P202, P260, P264, P270, P280, P314, P308+P313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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