Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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N-Nitrosomethylisopropylamine
Item number: TGM-T84938-10mg
Description: N-Nitrosomethylisopropylamine, a type of N-nitrosamine, has been shown to induce tumor formation in mice. Target: Others. Smiles: O=NN(C)C(C)C
| Keywords: | NMIPA |
| CAS | 30533-08-5 |
| MW: | 102.1346 D |
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(±)-N-desmethyl Venlafaxine hydrochloride
Item number: TGM-T84941-10mg
Description: (±)-N-desmethyl Venlafaxine, a minor active metabolite of venlafaxine, serves as a selective norepinephrine and serotonin reuptake inhibitor (SNRI). Generated through the metabolization by the cytochrome P450 (CYP) isoform CYP3A4, it exhibits reuptake inhibition of norepinephrine and serotonin in rat...
| Keywords: | Wy 45494 |
| Application: | Venlafaxine minor active metabolite |
| CAS | 93413-90-2 |
| MW: | 299.836 D |
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1-Carboxycyclohexaneacetic Acid
Item number: TGM-T84949-10mg
Description: 1-Carboxycyclohexaneacetic acid may be present as a potential impurity in commercial gabapentin, an antiepileptic drug. Furthermore, it serves as a precursor for synthesizing antagonists targeting the serotonin (5-HT) receptor subtype 5-HT2A. Target: Others. Smiles: OC(=O)CC1(CCCCC1)C(O)=O
| Keywords: | Gabapentin Impurity E |
| CAS | 67950-95-2 |
| MW: | 186.207 D |
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2-Aminotetralin
Item number: TGM-T84955-10mg
Description: 2-Aminotetralin acts as a neuromodulatory agent by inhibiting serotonin (5-HT) and norepinephrine reuptake in the rat brain at a dose of 39.4 mg/kg. It triggers hypothermia in rats through intracisternal or intraperitoneal injection, while the implantation of crystals in the hypothalamus' medial...
| Keywords: | 2-AT |
| CAS | 2954-50-9 |
| MW: | 147.2169 D |
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Rabeprazole sulfone
Item number: TGM-T84959-10mg
Description: Rabeprazole sulfone, a metabolite of the proton pump inhibitor rabeprazole, is produced via the cytochrome P450 (CYP) isoform CYP3A. Additionally, it has been identified as an impurity in bulk rabeprazole preparations. Target: Others. Smiles: COCCCOc1ccnc(CS(=O)(=O)c2nc3ccccc3[nH]2)c1C
| Application: | Rabeprazole metabolite |
| CAS | 117976-47-3 |
| MW: | 375.44 D |
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Faropenem sodium hydrate
Item number: TGM-T84966-10mg
Description: Faropenem sodium hemipentahydrate is an orally administered beta-lactam antibiotic within the penem group, exhibiting resistance to certain types of extended-spectrum beta-lactamase (beta-lactamase). Target: Others. Smiles:...
| Keywords: | Faropenem sodium hydrate, Faropenem sodium hemipentahydrate, (+)-Faropenem sodium hemipentahydrate |
| CAS | 158365-51-6 |
| MW: | 704.67 D |
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M04
Item number: TGM-T84969-10mg
Description: M04 acts as a stimulator of interferon genes (STING) agonist, effectively inducing IFN reporter gene expression in HEK293T cells equipped with wild-type human STING. Its activity is specific, not affecting HEK293T cells with the R71H-G230A-R293Q (HAQ) human STING variant or mouse RAW 264.7 cells,...
| Application: | STING agonist |
| CAS | 875158-73-9 |
| MW: | 428.58 D |
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Indomethacin Acyl Glucuronide
Item number: TGM-T84973-10mg
Description: Indomethacin acyl glucuronide, a metabolite of the COX inhibitor indomethacin (1), embodies an essential byproduct formed during the metabolic processing of indomethacin. Target: Others. Smiles: COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)O[C@H]3OC([C@H](O)[C@@H](O)[C@H]3O)C(O)=O)c2c1
| Keywords: | Indomethacin Acyl-beta-D-Glucuronide |
| CAS | 75523-11-4 |
| MW: | 533.91 D |
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DPPE-MPEG(2000)
Item number: TGM-T84980-10mg
Description: DPPE-MPEG(2000) is a polyethylene glycol (PEG) derivative of 1,2-dipalmitoyl-rac-glycero-3-phosphoethanolamine (DPPE), characterized as a PEGylated phospholipid. Target: Others
| Keywords: | 1,2-Dipalmitoyl-rac-glycero-3-PE-N-Polyethyleneglycol-2000 |
| CAS | 459429-07-3 |
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Descarbonyl Lacosamide
Item number: TGM-T84986-10mg
Description: Descarbonyl-lacosamide is a potential impurity in commercial lacosamide preparations. It is a degradation product that forms under acidic conditions. Target: Others. Smiles: COC[C@@H](N)C(=O)NCc1ccccc1
| Keywords: | DP-I |
| Application: | Lacosamide potential impurity found in commercial preparations |
| CAS | 196601-69-1 |
| MW: | 208.261 D |
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3'-deoxy Thymidine
Item number: TGM-T84987-10mg
Description: d2T, a nucleoside analog of thymidine, exhibits antiviral activity by inhibiting HIV replication in infected human peripheral blood mononuclear cells (PBMCs, EC50 = 0.17 µM). Additionally, 3'-deoxy Thymidine at concentrations of 1, 3, 10, or 30 µM significantly decreases viral plaque formation in CV-1...
| Keywords: | 2',3'-Dideoxythymidine |
| CAS | 3416-05-5 |
| MW: | 226.232 D |
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Hydroxy Celecoxib
Item number: TGM-T84997-10mg
Description: Hydroxy celecoxib, an inactive metabolite of celecoxib, is synthesized through the metabolism of celecoxib by cytochrome P450 (CYP) isoforms CYP2C9, CYP3A4, and CYP2D6 in human liver microsomes. Target: Others. Smiles: NS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(CO)cc1)C(F)(F)F
| CAS | 170571-00-3 |
| MW: | 397.37 D |
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