(±)-N-desmethyl Venlafaxine hydrochloride

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-T84941-10mg	10 mg				5 - 10 business days*		-
TGM-T84941-50mg	50 mg				5 - 10 business days*		-

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Description: (±)-N-desmethyl Venlafaxine, a minor active metabolite of venlafaxine, serves as a... more

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Product information "(±)-N-desmethyl Venlafaxine hydrochloride"

Description: (±)-N-desmethyl Venlafaxine, a minor active metabolite of venlafaxine, serves as a selective norepinephrine and serotonin reuptake inhibitor (SNRI). Generated through the metabolization by the cytochrome P450 (CYP) isoform CYP3A4, it exhibits reuptake inhibition of norepinephrine and serotonin in rat synaptosome preparations, demonstrated by IC50 values of 4.7 and 1.6 µM, respectively. Clinically, it has been shown to counteract reserpine-induced hypothermia in mice, displaying efficacy at a minimum effective dose (MED) of 10 mg/kg. Target: Others. Smiles: Cl.CNCC(c1ccc(OC)cc1)C1(O)CCCCC1

Keywords:	Wy 45494
Supplier:	TargetMol
Supplier-Nr:	T84941

Properties

Application:	Venlafaxine minor active metabolite
MW:	299.836 D
Formula:	C16H26ClNO2

Database Information

CAS :	93413-90-2\| Matching products
KEGG ID :	K17689 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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