Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Anticancer agent 144
Item number: TGM-T79845-50mg
Description: Compound 144 (also known as Anticancer Agent 144) is a potent inhibitor of both PTPN2 and PTP1B, exhibiting IC50 values of less than 2.5 nM, making it suitable for cancer research applications [1]. Target: Phosphatase
| CAS | 2948340-59-6 |
| MW: | 594.34 D |
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Friluglanstat
Item number: TGM-T79846-50mg
Description: Friluglanstat is an inhibitor of the enzyme prostaglandin E synthase (mPGES-1) and exhibits anti-inflammatory activity [1]. Target: PGE Synthase
| CAS | 1422203-86-8 |
| MW: | 516.9 D |
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Frunexian
Item number: TGM-T79847-50mg
Description: Frunexian (EP-7041) is a selective, potent inhibitor of coagulation factor XI/activated factor XI, specifically targeting XIa. It shows antithrombotic activity without bleeding risk in a rat mesenteric arterial puncture model and is applicable in extracorporeal membrane oxygenation (ECMO) research [1]....
| Keywords: | EP-7041 |
| Application: | Targets coagulation factor XI [EC:3.4.21.27] (F11) |
| CAS | 1803270-60-1 |
| MW: | 374.43 D |
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Icalcaprant
Item number: TGM-T79848-50mg
Description: Icalcaprant is a kappa-opioid receptor antagonist (KOR-A) that effectively blocks the kappa opioid receptors in the brain, which are implicated in various neurological and psychiatric conditions [1]. Target: Opioid Receptor
| CAS | 2227384-17-8 |
| MW: | 406.48 D |
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Irpagratinib
Item number: TGM-T79850-5mg
Description: Irpagratinib (ABSK011) is an orally active fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor with specificity for FGFR4, exhibiting an IC50 of less than 10 nM. It effectively inhibits FGFR4 auto-phosphorylation and disrupts subsequent signal transduction to downstream pathways....
| Keywords: | ABSK011 |
| CAS | 2230974-62-4 |
| MW: | 570.59 D |
213.00€
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Nevadistinel
Item number: TGM-T79855-50mg
Description: Nevadistinel (NYX-458, NYX-3054) is a positive allosteric modulator of the N-methyl-D-aspartate (NMDA) receptor, indicated for mitigating cognitive deficits related to neurodegenerative conditions, including mild cognitive impairment, mild Alzheimer's disease, Parkinson's disease, and Lewy body disease...
| Keywords: | NYX-3054, NYX-458 |
| Application: | Dementia therapeutic agent, NMDA receptor modulator |
| CAS | 2181816-92-0 |
| MW: | 274.32 D |
From 1,412.00€
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Resigratinib
Item number: TGM-T79856-50mg
Description: Resigratinib (KIN-3248) is an FGFR tyrosine kinase inhibitor with antineoplastic activity [1]. Target: FGFR
| Keywords: | KIN-3248 |
| CAS | 2750709-91-0 |
| MW: | 523.53 D |
From 266.00€
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Risevistinel
Item number: TGM-T79857-50mg
Description: Risevistinel (NYX-783), a positive allosteric modulator of the N-methyl-D-aspartate (NMDA) receptor, may mitigate cognitive deficits in neurodegenerative conditions, including mild cognitive impairment, mild Alzheimer's disease, Parkinson's disease, and Lewy body disease [1]. Target: iGluR
| Keywords: | NYX-783 |
| Application: | NMDA receptor modulator |
| CAS | 2591344-26-0 |
| MW: | 297.35 D |
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TIE-2/VEGFR-2 kinase-IN-3
Item number: TGM-T79858-50mg
Description: TIE-2/VEGFR-2 kinase-IN-3, a benzimidazole derivative, is a potent inhibitor of tyrosine kinase receptors TIE-2 and VEGFR-2, with IC50 values of 6.9 nM and 3.5 nM, respectively. This compound is useful for angiogenesis research [1]. Target: Others
| CAS | 433224-09-0 |
| MW: | 519.47 D |
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TIE-2/VEGFR-2 kinase-IN-4
Item number: TGM-T79859-50mg
Description: TIE-2/VEGFR-2 kinase-IN-4, a benzimidazole derivative, is a potent inhibitor of the tyrosine kinase receptors TIE-2 and VEGFR-2, with IC50 values of 5.2 nM and 5.1 nM, respectively. This compound is utilized in angiogenesis research [1]. Target: Others
| CAS | 433224-29-4 |
| MW: | 539.44 D |
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Tacaciclib
Item number: TGM-T79862-50mg
Description: Tacaciclib is a cyclin-dependent kinase (CDK) inhibitor with observed antineoplastic activity [1]. Target: CDK
| CAS | 2768774-66-7 |
| MW: | 528.65 D |
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Usnoflast
Item number: TGM-T79864-5mg
Description: Usnoflast functions as an NLRP3 modulator and also serves as a non-steroidal anti-inflammatory agent (NSAID) [1]. Target: NOD-like Receptor (NLR)
| CAS | 2455519-86-3 |
| MW: | 403.54 D |
902.00€
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