Irpagratinib

Irpagratinib
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T79850-5mg 5 mg

5 - 10 business days*

213.00€
 
Description: Irpagratinib (ABSK011) is an orally active fibroblast growth factor receptor (FGFR)... more
Product information "Irpagratinib"
Description: Irpagratinib (ABSK011) is an orally active fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor with specificity for FGFR4, exhibiting an IC50 of less than 10 nM. It effectively inhibits FGFR4 auto-phosphorylation and disrupts subsequent signal transduction to downstream pathways. Demonstrating high exposure in pharmacokinetic studies in mice, rats, and dogs, Irpagratinib also displays antineoplastic activity in subcutaneous xenograft tumor models [1]. Target: FGFR
Keywords: ABSK011
Supplier: TargetMol
Supplier-Nr: T79850

Properties

MW: 570.59 D
Formula: C28H32F2N6O5

Database Information

CAS : 2230974-62-4| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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