Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Ifenprodil hemitartrate
Item number: TGM-T41182-10mg
Description: Ifenprodil hemitartrate is a NMDA receptor antagonist, acting at the polyamine site. Also analpha-adrenergic vasodilator.sigma2ligand displaying about 3-fold selectivity oversigma1sites. Target: Others. References: Gotti et al (1988) Ifenprodil and SL-82,0715 as cerebral anti-ischemic agents. 1....
From 406.00€
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Helianorphin-19
Item number: TGM-T41183-1mg
Description: Helianorphin-19 is a high affinity, potent and selective kappa-opioid receptor (KOR) agonist (Ki = 25 nM, EC50= 45 nM). Helianorphin-19 exhibits approximately 200-fold selectivity for KOR over µ and delta-opioid receptors.In vivoHelianorphin-19 shows potent peripheral analgesic efficacy in a mouse model...
1,023.00€
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BIBP 3226 trifluoroacetate
Item number: TGM-T41188-2mg
Description: BIBP 3226 trifluoroacetate is a mixed non-peptide neuropeptide Y Y1(NPY Y1) and neuropeptide FF (NPFF) receptor antagonist (Kivalues are 1.1, 79, 108, > 1000, > 1000 and >1000 for rNPY Y1, hNPFF2, rNPFF, rNPY Y2, rNPY Y4and rNPY Y5respectively). Produces an anxiogenic-like effect in rats following...
750.00€
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CNV Dopamine
Item number: TGM-T41192-5mg
Description: CNV Dopamine is a carboxynitroveratryl (CNV)-caged dopamine, releases dopamine upon ultraviolet light stimulation (365 nm). Induces dopaminergic currents upon photolysis in brain slices expressing wild-type or GFP-labeled D2receptors. Displays no decrease in current (rundown) with UV light flash...
1,222.00€
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FFN 270
Item number: TGM-T41193-5mg
Description: FFN 270 is a fluorescent false neurotransmitter (FFN). Fluorescent substrate for NET and VMAT2. Labels noradrenergic neurons and their synaptic vesicles, and enables imaging of synaptic vesicle content release from specific axonal sitesin vivo. Selectively labels NA neurons over other monoamine and CNS...
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Phalloidin-Janelia Fluor(R)646
Item number: TGM-T41197-12ug
Description: Phalloidin-Janelia Fluor(R)646 is a red fluorescent F-actin probe. Phalloidin-Janelia Fluor(R)646 is composed of the F-actin probe, Phalloidin, conjugated to Janelia Fluor(R)646. It is suitable for use in confocal and super-resolution microscopy techniques such as dSTORM. Excitation/emission maximum...
| Keywords: | Phalloidin-JF646, Phalloidin-Janelia Fluor(R)646 |
1,602.00€
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cis-SIM1
Item number: TGM-T41199-5mg
Description: cis-SIM1 is the negative control for SIM1. Target: Others
| Keywords: | cis-SIM1 |
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TP 472N
Item number: TGM-T41202-5mg
Description: TP 472N is a negative control forTP 472. Inactive against other bromodomains (>20µM against BRD9). Target: Others
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TAT-Gap19(I130A)
Item number: TGM-T41204-5mg
Description: TAT-Gap19(I130A) is a control peptide for TAT-Gap19, a Cx43 hemichannel blocker. TAT-Gap19(I130A) consists of TAT-GAP19 with a I130A amino acid residue change at a key residue for GAP19 activity. In C6 glioma cells expression Cx43, TAT-GAP19(1130A) does not inhibit [Ca2+]i-triggered ATP release at 200...
| Keywords: | TAT-Gap19(I130A) |
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3',3'-cGAMP sodium salt
Item number: TGM-T41205-5mg
Description: 3',3'-cGAMP sodium salt is a STING agonist. Reduces B cell proliferation and induces apoptosis of malignant B cellsin vitro. Suppresses 5TGM1 multiple myeloma xenograft growth in immunodeficient mice, and induces leukemic regression in Eµ-TCL1 mice. Target: Others. References: Tang et al (2016)...
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DPNB-ABT 594
Item number: TGM-T41209-5mg
Description: DPNB-ABT 594 is a nitrobenzyl-caged ABT 594, a selective alpha4beta2 nAChR agonist. One-photon uncaging evokes large inward currents and Ca2+transients on cell bodies and dendrites of medial habenular neurons in mouse brain slices. Two-photon uncaging induces fast nAChR-mediated currents. Photolyzed...
1,061.00€
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PA Nic
Item number: TGM-T41210-500ug
Description: PA Nic is a coumarin-caged nicotine. Releases nicotine when exposed to 390 ± 10 nm wavelength light (lambdamax = 404 nm). Suitable for two-photon uncaging at <900 nm (Maximum two-photon cross-section at 810 nm). Extinction coefficient (epsilon) 17,400 M-1cm-1. Evokes nicotinic currents in mouse brain...
1,877.00€
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