Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Mpro inhibitor N3 hemihydrate
Item number: TGM-T38174-25mg
Description: Mpro inhibitor N3 hemihydrate is a potent antagonist of the SARS-CoV-2 main protease (Mpro), with an EC50 of 16.77 µM against SARS-CoV-2. It specifically inhibits Mpro in various coronaviruses, including SARS-CoV, MERS-CoV, HCoV-229E (IC50 4.0 µM), FIPV (IC50 8.8 µM), and MHV-A59 (IC50 2.7 µM) [1][2]....
From 108.00€
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Tyr-alpha-CGRP (rat) (trifluoroacetate salt)
Item number: TGM-T38190-1mg
Description: Tyr-alpha-CGRP (rat) is an N-terminally tyrosinated analog of the neuropeptide alpha-CGRP that induces a fall in resting tension of isolated opossum internal anal sphincter (IAS) with an EC50 value of 178 nM. Target: Others
1,032.00€
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beta-Endorphin (1-27) (human) (trifluoroacetate salt)
Item number: TGM-T38193-1mg
Description: beta-Endorphin (1-27) is an endogenous peptide that binds to µ-, delta-, and kappa-opioid receptors (Kis = 5.31, 6.17, and 39.82 nM, respectively, in COS-1 cells expressing rat receptors). It binds to rat and mouse brain membrane preparations (IC50s = 1.1 and 5.7 nM, respectively) and induces chemotaxis...
812.00€
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JF-NP-26
Item number: TGM-T38229-5mg
Description: Caged Raseglurant . Releases raseglurant upon exposure to 405 nm (violet) light. Inhibits the effects of Quisqualate in cultured neurons when exposed to 405 nm light. Exhibits analgesic activity in pain models in vivo on photoactivation. Quantum yield = 0.18. Target: Others. References: Font et al...
376.00€
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HCoV-229E-IN-1
Item number: TGM-T38234-100mg
Description: HCoV-229E-IN-1 is a potent inhibitor of HCoV-229E replication, demonstrating efficacy with EC50 values of 0.65 µM in MTS cells and 0.6 µM in CPE cells[1]. Target: Others. References: Stevaert A, et, al. Betulonic Acid Derivatives Interfering with Human Coronavirus 229E Replication via the nsp15...
From 297.00€
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Lactoferricin B (4-14), bovine TFA
Item number: TGM-T38247-10mg
Description: Lactoferricin B (4-14), bovine (TFA), is a peptide derived from residues 4-14 of bovine lactoferrin, exhibiting broad-spectrum antimicrobial activity against various microorganisms[1]. References: John S Mj?en Svendsen, et al. Very Short and Stable Lactoferricin-Derived Antimicrobial Peptides: Design...
From 436.00€
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Cathepsin D and E FRET Substrate acetate(839730-93-7 Free...
Item number: TGM-T38254-10mg
Description: Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate selectively cleaved by cathepsins D and E at the Phe-Phe amide bond, demonstrating no activity towards cathepsins B, H, or L. This specificity renders it essential for routine assays and mechanistic studies focusing on cathepsins E and...
From 218.00€
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Deltorphin II (trifluoroacetate salt)
Item number: TGM-T36722-10mg
Description: Deltorphin II is a peptide agonist of delta2-opioid receptors.1,2It is selective for delta-opioid receptors over µ- and kappa-opioid receptors in radioligand bindings assays (Kis = 0.0033, >1, and >1 µM, respectively) and induces [35S]GTPgammaS binding in mouse brain membrane preparations (EC50= 0.034...
From 250.00€
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Urotensin II (goby) (trifluoroacetate salt)
Item number: TGM-T36729-1mg
Description: Urotensin II is a peptide vasoconstrictor and agonist of the urotensin (UT) receptor (Ki= 2.06 nM for the human recombinant receptor expressed in HEK293 cells).1It stimulates intracellular calcium mobilization in HEK293 cells expressing human and rat UT (EC50s = 0.47 and 0.78 nM, respectively) but...
405.00€
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Prednisone 21-aldehyde/22-hydroxy Prednisone
Item number: TGM-T36739-1mg
Description: Prednisone 21-aldehyde is a derivative of the synthetic corticosteroid prednisone that has antiviral activity against influenza virus A-PR8 in embryonated chicken eggs. 22-hydroxy Prednisone is an unstable adduct of prednisone. It has been observed following incubation of prednisone with nornicotine....
111.00€
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Guanosine 5'-diphosphate (sodium salt hydrate)
Item number: TGM-T36740-10mg
Description: Guanosine 5'-diphosphate (GDP) is a purine nucleotide and biosynthetic precursor of guanosine 5'-triphosphate .1It has been used to study the conformations of GTPases.2GDP (100 µM) activates sulfonylurea receptor 2B (SUR2B) linked to the inward-rectifier potassium channel 6.1 (Kir6.1) in HEK293T cells...
From 34.00€
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CDK7/9 tide
Item number: TGM-T36743-10mg
Description: CDK7/9 tide is a peptide substrate for CDK7 or CDK9[1]. References: Robert T, et, al. Development of a CDK10/CycM in vitro Kinase Screening Assay and Identification of First Small-Molecule Inhibitors. Front Chem. 2020 Feb 27, 8:147.
From 156.00€
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