Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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PDE7A-IN-1
Item number: TGM-T205476-10mg
Description: PDE7A-IN-1 (Compound 26) is an orally active PDE7A inhibitor with an IC50 value of 3.7 nM. By inhibiting sclerostin, PDE7A-IN-1 significantly enhances bone mineral density, making it suitable for studies on osteoporosis and related bone metabolic disorders. Target: PDE
| MW: | 463.96 D |
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EGFR/VEGFR2-IN-5
Item number: TGM-T205483-10mg
Description: EGFR/VEGFR2-IN-5 (Compound 14) is an orally active dual inhibitor of EGFR and VEGFR2, exhibiting an IC50 value of 1.15 µM for VEGFR2 and 0.28 µM for EGFRT790M. This compound demonstrates significant anticancer activity. Target: VEGFR, EGFR
| MW: | 429.41 D |
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SARS-CoV-2 Mpro-IN-38
Item number: TGM-T206175-10mg
Description: SARS-CoV-2 Mpro-IN-38 (2-5a) is an inhibitor of SARS-CoVâ??2 Mpro with an IC50 value of 0.0435 µM. Target: SARS-CoV, Virus Protease
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MS9024
Item number: TGM-T206183-10mg
Description: MS9024 is a degrader of DNA methyltransferase 1 (DNMT1), facilitating its degradation in HCT116 cells via the ubiquitin-proteasome pathway, with a DC50 of 35 nM (DC50 values are 254 nM in MDA-MB-468 and 101 nM in H1299). Additionally, MS9024 inhibits DNMT1 with an IC50 of 0.43 µM. Target: DNA...
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Mpro/PLPro-IN-2
Item number: TGM-T206191-10mg
Description: Mpro/PLPro-IN-2 (Compound 22l) is a non-covalent competitive dual inhibitor of SARS-CoV-2's papain-like protease and main protease, exhibiting a Ki of 0.2 µM for the papain-like protease and 1.1 µM for the main protease. Mpro/PLPro-IN-2 is applicable in research related to anti-SARS-CoV-2 efforts....
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Fomesafen
Item number: TGM-T20622-25mg
Description: Fomesafen (PP-021) is a diphenyl ether herbicide and an inhibitor of efficient and selective protoporphyrinogen IX oxidase (PPO). Target: Others. Smiles: C(NS(C)(=O)=O)(=O)C1=C(N(=O)=O)C=CC(OC2=C(Cl)C=C(C(F)(F)F)C=C2)=C1
| Keywords: | PP021 , PP-021 , PP 021 |
| MW: | 438.76 D |
30.00€
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CSF1R-IN-26
Item number: TGM-T206224-10mg
Description: CSF1R-IN-26 (Compound III-1) is an inhibitor of CSF-1R with an IC50 of 20.07 nM. It promotes the polarization of M2 macrophages to M1 macrophages, inducing apoptosis in MC-38 cancer cells. CSF1R-IN-26 inhibits the activation of the AKT/ERK/STAT3 signaling pathways, remodels the tumor immune...
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FITC-PEG-N3 (MW 10000)
Item number: TGM-T206228-10mg
Description: FITC-PEG-N3 (MW 10000) is an azide fluorescent dye composed of polyethylene glycol (PEG) and FITC. This click chemistry reagent contains an azide group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkynyl-containing molecules. It can also participate in a...
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YAP-IN-1
Item number: TGM-T206234-10mg
Description: YAP-IN-1 (Compound (+)-1) is an autophagy inhibitor specifically targeting YAP1. It binds to the Hippo pathway transcription factor YAP1 with a Kd of 9.13 µM, promoting its degradation through the chaperone-mediated autophagy (CMA) pathway. This process inhibits the Rab7-mediated fusion of...
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SrtA-IN-1
Item number: TGM-T206239-10mg
Description: SrtA-IN-1 (Compound T10) is an inhibitor of Streptococcus pyogenes sortase A (SpSrtA) with an IC50 value of 0.7 µM. It is applicable for research in the field of anti-infective agents. Target: Antibacterial
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FITC-mPEG (MW 1000)
Item number: TGM-T206240-10mg
Description: FITC-mPEG (MW 1000) is a fluorescent dye composed of methoxy polyethylene glycol (mPEG) and FITC. It is applicable for fluorescence labeling and imaging.
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Cy3-PEG-N3 (MW 5000)
Item number: TGM-T205478-10mg
Description: Cy3-PEG-N3 (MW 5000) is a fluorescent dye known as Cy3 azide, specifically designed for peptide, protein, and oligonucleotide amino groups. As a click chemistry reagent, it contains an azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAC) with alkyne-containing molecules....
| MW: | 5000 D |
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