Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
No results were found for the filter!
LY 3000328
Item number: TGM-TQ0116-100mg
Description: LY 3000328 (Cathepsin S inhibitor) is a potent, highly selective Cathepsin S (Cat S) inhibitor (IC50s: 7.7 and 1.67 nM for hCat S and mCat S). Target: Cysteine Protease. Smiles: CNC(=O)O[C@H]1COc2ccc(cc2[C@@H]1NC(=O)c1ccc(F)cc1)N1CCN(CC1)C1COC1. References: Jadhav PK, et al. Discovery of Cathepsin S...
| Keywords: | Cathepsin S inhibitor |
| Application: | Potent cathepsin S inhibitor |
| CAS | 1373215-15-6 |
| MW: | 484.52 D |
From 91.00€
*
Britannilactone
Item number: TGM-TQ0118-10mg
Description: Britannilactone (Desacetylinulicin) is a sesquiterpene from Inula britannica with anti-inflammatory and anti-tumor activity.Britannilactone has been associated with this antimelanotic activity and can be used in studies of skin whitening. Smiles:...
| Keywords: | Desacetylinulicin |
| CAS | 33620-72-3 |
| MW: | 266.33 D |
From 67.00€
*
Cirsimaritin
Item number: TGM-TQ0119-10mg
Description: Cirsimaritin exhibits antibacterial, anti-inflammation, anti-tumor, antioxidant properties and renal protection. Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors. Target: GABA Receptor. Smiles: COc1cc2oc(cc(=O)c2c(O)c1OC)-c1ccc(O)cc1. References: Quan Z, et al. Reactive oxygen...
| CAS | 6601-62-3 |
| MW: | 314.29 D |
From 49.00€
*
CDDO-Im
Item number: TGM-TQ0120-100mg
Description: CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARalpha/PPARgamma). Target: PPAR, Others, Ferroptosis, Nrf2. Smiles: [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)[C@]2([H])C(=O)C=C2[C@@]1(C)CC[C@@]1([H])C(C)(C)C(=O)C(=C[C@]21C)C#N)C(=O)n1ccnc1. References: Place AE, et al. The novel...
| Keywords: | CDDO-Imidazolide, RTA-403, TP-235 |
| Application: | Nrf2 signaling activator |
| CAS | 443104-02-7 |
| MW: | 541.72 D |
From 30.00€
*
VH-298
Item number: TGM-TQ0121-100mg
Description: VH-298 is a potent inhibitor of VHL that stabilizes HIF-alpha and elicits a hypoxic response via a different mechanism, that is the blockade of the VHL:HIF-alpha protein-protein interaction downstream of HIF-alpha hydroxylation by PHD enzymes. Target: HIF, Ligand for E3 Ligase, Others. Smiles:...
| Application: | Protac(R) reagent |
| CAS | 2097381-85-4 |
| MW: | 523.65 D |
From 38.00€
*
VCH-916
Item number: TGM-TQ0122-2mg
Description: VCH-916 is a new nonnucleoside inhibitor of HCV NS5B polymerase. Target: HCV Protease. Smiles: O=C(C1=C(N([C@H]2CC[C@H](OC)CC2)C([C@H]3CC[C@H](C)CC3)=O)C=C(C4=CCCCC4)S1)O[K]. References: Abdelrahman S. Mayhoub. Hepatitis C RNA-dependent RNA polymerase inhibitors: A review of structure-activity and...
| CAS | 1200133-34-1 |
| MW: | 497.73 D |
From 75.00€
*
VCH-916 free acid(1200133-34-1 free base)
Item number: TGM-TQ0122L-100mg
Description: VCH-916 is a novel nonnucleoside HCV NS5B polymerase inhibitor. Target: HCV Protease. Smiles: N(C(=O)[C@@H]1CC[C@@H](C)CC1)(C2=C(C(O)=O)SC(=C2)C=3CCCCC3)[C@@H]4CC[C@@H](OC)CC4. References: Ludmila Gerber, Tania M. Welzel, Stefan Zeuzem. New therapeutic strategies in HCV: polymerase inhibitors. Liver...
| CAS | 914778-92-0 |
| MW: | 459.64 D |
From 65.00€
*
MC 1046
Item number: TGM-TQ0123-1mg
Description: MC 1046 is an impurity of Calcipotriol. Calcipotriol is a ligand of VDR-like receptors. Target: Others. Smiles: C[C@H](\C=C\C(=O)C1CC1)[C@H]1CCC2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C. References: Wietrzyk et al (2007) Antitumor properties of diastereomeric and geometric analogs of vitamin D3....
| Keywords: | Impurity A of Calcipotriol |
| CAS | 126860-83-1 |
| MW: | 410.59 D |
386.00€
*
BETP
Item number: TGM-TQ0124-100mg
Description: BETP is an agonist of GLP-1 receptor (EC50s: 0.66 and 0.755 µM for human and rat GLP-1 receptor). Target: Glucagon Receptor. Smiles: CCS(=O)c1nc(cc(n1)C(F)(F)F)-c1cccc(OCc2ccccc2)c1. References: Sloop KW, et al. Novel small molecule glucagon-like peptide-1 receptor agonist stimulates insulin secretion...
| Application: | Positive allosteric GLP-1R modulator |
| CAS | 1371569-69-5 |
| MW: | 406.42 D |
From 39.00€
*
Mirodenafil dihydrochloride
Item number: TGM-TQ0126-100mg
Description: Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction. Target: PDE. Smiles: Cl.Cl.CCCOc1ccc(cc1-c1nc2c(CCC)cn(CC)c2c(=O)[nH]1)S(=O)(=O)N1CCN(CCO)CC1. References: Paick, J.S., et al., Efficacy and safety of mirodenafil, a new oral phosphodiesterase type 5...
| Keywords: | SK-3530 dihydrochloride |
| Application: | PDE5 inhibitor |
| CAS | 862189-96-6 |
| MW: | 604.59 D |
From 30.00€
*
Navtemadlin
Item number: TGM-TQ0127-100mg
Description: Navtemadlin (AMG232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction (IC50: 0.6 nM). It binds to MDM2 with a Kd of 0.045 nM. Target: E1/E2/E3 Enzyme, Mdm2. Smiles: CC(C)[C@@H](CS(=O)(=O)C(C)C)N1[C@@H]([C@H](C[C@](C)(CC(O)=O)C1=O)c1cccc(Cl)c1)c1ccc(Cl)cc1. References: Canon...
| Keywords: | AMG232, CS-1300 |
| Application: | Targets E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27] (MDM2) |
| CAS | 1352066-68-2 |
| MW: | 568.55 D |
From 64.00€
*
Furilazole
Item number: TGM-TQ0128-10mg
Description: Furilazole (MON 13900) is a herbicide. Target: Others. Smiles: C(C(Cl)Cl)(=O)N1CC(OC1(C)C)C2=CC=CO2
| Keywords: | MON 13900 |
| CAS | 121776-33-8 |
| MW: | 278.13 D |
From 34.00€
*