Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
No results were found for the filter!
HSN748
Item number: TGM-T204396-10mg
Description: HSN748 is an analog of ponatinib and acts as a multi-kinase inhibitor. It exhibits inhibitory activity against kinases such as FLT3, ABL1, RET, PDGFRalpha/beta, MNK1, and MNK2. HSN748 can suppress the growth of chronic myeloid leukemia and acute myeloid leukemia cell lines, making it a useful compound...
| MW: | 519.521 D |
Please request pricing for this article.
VEGFR-2-IN-60
Item number: TGM-T204408-10mg
Description: VEGFR-2-IN-60 (compound 5c) is a potent VEGFR-2 inhibitor with an IC50 of 1.07 nM and exhibits cytotoxic activity against HCC1806, Hela, and A549 cell lines. Target: VEGFR. Smiles: COC1=C(C=C2C(=C1)C(=NC=N2)OC3=CC4=C(C=C3)C=C(O4)C(=O)/C=C/C5=CNC6=CC=CC=C65)OC
| MW: | 491.494 D |
Please request pricing for this article.
Corannulene
Item number: TGM-T204413-10mg
Description: Corannulene is an agonist of the aromatic hydrocarbon receptor (AhR). It induces a lower cytotoxic response in liver cancer cells compared to Benzo[a]pyrene and shows potential for use in cancer research. Target: Aryl Hydrocarbon Receptor. Smiles: C1=CC=2C=CC3=CC=C4C=CC5=CC=C1C=6C2C3=C4C56
| MW: | 250.293 D |
Please request pricing for this article.
DNA ligase-IN-2
Item number: TGM-T204415-10mg
Description: DNA ligase-IN-2 (compound 2) acts as a potent LigA inhibitor, effectively hindering the DNA-independent spontaneous adenylation activity of full-length LigA and the truncated enzyme LigA:AD with an IC50 of 29 nM. It also significantly suppresses the in vitro growth of Staphylococcus aureus, showing MIC...
| MW: | 273.219 D |
Please request pricing for this article.
LD4172
Item number: TGM-T204416-10mg
Description: LD4172 is a PROTAC degrader capable of degrading RIP kinase (RIPK1) with a DC50 in the nanomolar range. When used in combination with TNF-alpha, LD4172 can induce apoptosis in B16F10 cells. In mouse models, it demonstrates antitumor activity. (Pink: ligand for target protein, Black: linker, Blue: ligand...
| MW: | 1149.37 D |
Please request pricing for this article.
JD118
Item number: TGM-T204417-10mg
Description: JD118 is an inhibitor of JNK. It effectively suppresses the activity of JNK1 and the expression of cJun (1 - 135). Target: JNK. Smiles: N1=C(SC=C1C=2SC(=NC2C)N)NC=3C=CC=CC3
| MW: | 288.391 D |
Please request pricing for this article.
Mycobacterium Tuberculosis-IN-6
Item number: TGM-T204419-10mg
Description: Mycobacterium Tuberculosis-IN-6 (compound b1) is an inhibitor of the enoyl reductase InhA from Mycobacterium tuberculosis, with an IC50 value of 7.74 µM. It is useful in antibacterial research. Target: Antibacterial. Smiles: O=C(C=1C=CC=CC1F)N2CCC(CC=3C=CC=CC3)CC2
| MW: | 297.367 D |
Please request pricing for this article.
XPO1-ligand-1
Item number: TGM-T204420-10mg
Description: XPO1-ligand-1 is a target protein ligand for XPO1, and it can be utilized in the synthesis of PROTAC XPO1 degrader-1. Target: Ligands for Target Protein for PROTAC, CRM1. Smiles: CC1=C(C(=O)N(C1=O)NC2=NC(=C(C=C2)C(F)(F)F)Cl)CCC(=O)CO
| MW: | 391.73 D |
Please request pricing for this article.
NSD2-PWWP1-IN-3
Item number: TGM-T204424-10mg
Description: NSD2-PWWP1-IN-3 (compound 36) is an effective inhibitor of NSD2-PWWP1, with an IC50 value of 8.05 µM. It has potential applications in cancer research. Target: Histone Methyltransferase. Smiles: N#CC=1C=CC(=C2C=CC=CC12)C3=C(N=CN3C)C=4C(=CC(=CC4C)CN5CCC(NC(=O)OC(C)(C)C)CC5)C
| MW: | 549.706 D |
Please request pricing for this article.
Tyrosylleucine
Item number: TGM-T20443-25mg
Description: Tyrosylleucine is a dipeptide composed of tyrosine and leucine. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis. Smiles:...
| Keywords: | Tyr-leu , L-Tyrosyl-L-leucine |
| MW: | 294.35 D |
From 1,440.00€
*
MAT2A-IN-19
Item number: TGM-T204432-10mg
Description: MAT2A-IN-19 (Compound I-3) is an inhibitor of methionine adenosyltransferase 2A (MAT2A), with an IC50 of 32.93 nM. Target: Methionine Adenosyltransferase (MAT). Smiles: O=C1C(=NC=2C=NC(=NC2N1C3=CC=C(OC(F)F)C=C3)OCC(F)(F)F)C=4C=CC5=NN(C=C5C4)C
| MW: | 518.396 D |
Please request pricing for this article.
ZCL279
Item number: TGM-T204446-10mg
Description: ZCL279 is a small molecule modulator (SMM) that inhibits the interaction between CDC42 and intersectin (ITSN). At lower concentrations (<10 µM), ZCL279 activates Cdc42, a cytoplasmic small GTPase in the Ras superfamily, while at higher concentrations (<10 µM) it significantly inhibits it. Target: Ras....
| MW: | 510.539 D |
Please request pricing for this article.