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Products from TargetMol

TargetMol

TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.

More information at: www.targetmol.com

Go to the catalogs of TargetMol

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mPGES-1-IN-1
mPGES-1-IN-1

Item number: TGM-T61718-100mg

TargetMol
Description: MPGES-1, a promising therapeutic target for the next generation of anti-inflammatory drugs in treating inflammatory diseases, possesses an IC50 value of 0.03 µM for mPGES-1-IN-1. Target: Others
MW: 386.43 D
From 1,440.00€ *
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Pol I-IN-1
Pol I-IN-1

Item number: TGM-T61720-100mg

TargetMol
Description: Pol I-IN-1 is a potent inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, with an inhibition concentration (IC50) of 0.21 µM [1]. Target: Others
MW: 386.45 D
From 1,440.00€ *
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SS-RJW100
SS-RJW100

Item number: TGM-T61723-100mg

TargetMol
Description: SS-RJW100 is an enantiomer of RJW100, known as a racemic agonist that targets two nuclear receptors: liver receptor homolog 1 (LRH-1) and steroidogenic factor 1 (SF-1). In vitro experiments reveal that SS-RJW100 promotes the recruitment of coregulator protein fragments and enhances the interaction with...
MW: 386.57 D
From 1,440.00€ *
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SB 258741 hydrochloride
SB 258741 hydrochloride

Item number: TGM-T61724-100mg

TargetMol
Description: SB 258741 hydrochloride is a potent antagonist of the 5-HT 7 receptor, designed specifically for studying schizophrenia [1]. Target: Others
MW: 386.98 D
From 1,440.00€ *
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VU0463271 quarterhydrate
VU0463271 quarterhydrate

Item number: TGM-T61725-100mg

TargetMol
Description: VU0463271 quarterhydrate is a potent KCC2 antagonist with an IC50 of 61 nM [1]. Target: Others
MW: 387 D
From 1,450.00€ *
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EGFR/HER2-IN-6
EGFR/HER2-IN-6

Item number: TGM-T61732-100mg

TargetMol
Description: EGFR/HER2-IN-6 (compound 43) is a dual EGFR/HER2 and DHFR inhibitor with potent activity against EGFR kinase, HER2 kinase, and DHFR, characterized by IC50 values of 0.122 µM, 0.078 µM, and 0.585 µM, respectively. This compound displays notable anticancer properties in various cancer cell lines, while...
MW: 387.46 D
From 1,440.00€ *
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Quorum Sensing-IN-1
Quorum Sensing-IN-1

Item number: TGM-T60595-100mg

TargetMol
Description: Quorum Sensing-IN-1 [QSI-1] is a small-molecule inhibitor targeting quorum sensing. Target: Others
MW: 290.36 D
From 1,440.00€ *
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hCAIX/XII-IN-5
hCAIX/XII-IN-5

Item number: TGM-T60602-100mg

TargetMol
Description: hCAIX/XII-IN-5 (Coumarin 9a) is an inhibitor of carbonic anhydrase (CA) with excellent selectivity for hCA IX/XII, displaying Kis of 93.3 nM and 85.7 nM over hCA I and hCA II, respectively. It exhibits anti-proliferative activities in cancer cells, delaying the cell cycle and inducing apoptosis [1]....
MW: 291.3 D
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Antibacterial agent 80
Antibacterial agent 80

Item number: TGM-T60634-100mg

TargetMol
Description: Antibacterial agent 80 (compound 20) demonstrates antibacterial activity [1]. Target: Others
MW: 295.47 D
From 1,440.00€ *
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EGFR/HER2/DHFR-IN-1
EGFR/HER2/DHFR-IN-1

Item number: TGM-T61596-100mg

TargetMol
Description: EGFR/HER2/DHFR-IN-1 is a highly selective and potent anticancer compound targeting MCF-7 breast cancer cells, acting as a multi-inhibitor for EGFR/HER2 kinase and DHFR enzymes, with IC50 values of 0.153 µM, 0.108 µM, and 0.291 µM, respectively. It induces cell cycle arrest at the G1/S phase and...
MW: 379.23 D
From 1,440.00€ *
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TLR7/8 antagonist 2
TLR7/8 antagonist 2

Item number: TGM-T61601-100mg

TargetMol
Description: TLR7/8 antagonist 2 (Compound 15) is a highly potent and orally active agonist of TLR7/8 with IC50 values of 4.9 nM for TLR7 and 0.6 nM for TLR8, making it a promising candidate for treating and investigating autoimmune diseases like lupus erythematosus, which involves inappropriate activation of TLR7...
MW: 379.47 D
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Anticancer agent 35
Anticancer agent 35

Item number: TGM-T61602-100mg

TargetMol
Description: Anticancer agent 35 (compound 10), a sulfonylurea derivative, is a potent anticancer agent that inhibits A549, A431, and PACA2 cell growth with IC50 values of 18.1 µg/mL, 4.0 µg/mL, and 18.9 µg/mL, respectively [1]. Target: Others
MW: 379.48 D
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12281 from 12289 pages
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