EGFR/HER2/DHFR-IN-1

Description: EGFR/HER2/DHFR-IN-1 is a highly selective and potent anticancer compound targeting MCF-7 breast cancer cells, acting as a multi-inhibitor for EGFR/HER2 kinase and DHFR enzymes, with IC50 values of 0.153 µM, 0.108 µM, and 0.291 µM, respectively. It induces cell cycle arrest at the G1/S phase and apoptosis in cells [1]. Target: Others