Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Antineoplaston A10
Item number: TGM-T7131-200mg
Description: Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer. Target: Apoptosis, Bcl-2 Family, MDM-2/p53, Ras, Endogenous Metabolite. Smiles: O=C(Cc1ccccc1)N[C@H]1CCC(=O)NC1=O. References: Tsuda H , Iemura A , Sata M , et al....
| Keywords: | NSC-648539 |
| MW: | 246.26 D |
From 38.00€
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Alagebrium chloride
Item number: TGM-T7143-100mg
Description: Alagebrium chloride (ALT711) is an advanced glycation end product (AGE) inhibitor that has proven effective in reducing systolic blood pressure and providing therapeutic benefits for patients with diastolic. Target: Endogenous Metabolite. Smiles: [Cl-].Cc1sc[n+](CC(=O)c2ccccc2)c1C. References: Jin-Bae K...
| Keywords: | ALT711 |
| MW: | 267.77 D |
From 30.00€
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JH-II-127
Item number: TGM-T7155-200mg
Description: JH-II-127 is an oral inhibitor of leucine-rich repeat kinase 2 (LRRK2), targeting WT LRRK2, G2019S LRRK2, and A2016T LRRK2 with IC50 values of 6.6 nM, 2.2 nM, and 47.7 nM, respectively. Target: LRRK2. Smiles: CNc1nc(Nc2ccc(cc2OC)C(=O)N2CCOCC2)nc2[nH]cc(Cl)c12. References: Discovery of a...
| MW: | 416.86 D |
From 37.00€
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Levalbuterol tartrate
Item number: TGM-T7164-200mg
Description: Levalbuterol tartrate is a short-acting beta2-adrenergic receptor agonist and the R enantiomer of salbutamol. Target: Adrenergic Receptor. Smiles: O[C@H]([C@@H](O)C(O)=O)C(O)=O.CC(C)(C)NC[C@H](O)c1ccc(O)c(CO)c1.CC(C)(C)NC[C@H](O)c1ccc(O)c(CO)c1. References: Jantikar A, et al. Comparison of...
| Keywords: | Levosalbutamol tartrate |
| MW: | 389.39 D |
From 30.00€
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(2-Chloropyridin-4-yl)MethanaMine Hydrochloride
Item number: TGM-T7185-25mg
Description: (2-Chloropyridin-4-yl)methanamine hydrochloride is a selective LOXL2 inhibitor with an IC50 of 126 nM. Target: Monoamine Oxidase. Smiles: Cl.NCc1ccnc(Cl)c1. References: Hutchinson J H , Rowbottom M W , Lonergan D , et al. Small Molecule Lysyl Oxidase-like 2 (LOXL2) Inhibitors: The Identification of an...
| MW: | 179.05 D |
From 35.00€
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Protirelin
Item number: TGM-T6956-100mg
Description: Protirelin (Thyroliberin) is a tripeptide that stimulates the release of thyrotropin and prolactin. Target: Endogenous Metabolite, Thyroid hormone receptor(THR). Smiles: C([C@H](CC1=CN=CN1)NC(=O)[C@@H]2CCC(=O)N2)(=O)N3[C@H](C(N)=O)CCC3. References: Noda Y,etal.Hyperthermia induced by...
| Keywords: | Lopremone , pGlu-His-Pro-NH2 , Synthetic thyrotropin-releasing hormone , Thyroliberin , TRH , TRF |
| MW: | 362.38 D |
From 31.00€
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Nudifloric Acid
Item number: TGM-T6981-200mg
Description: 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid (Nudifloric Acid) from Cordyceps bassiana targets to block AP-1-mediated luciferase activity, implying an anti-inflammatory function. Target: Others, DNA/RNA Synthesis. Smiles: CN1C=C(C=CC1=O)C(O)=O. References: Suh W , Nam G , Yang W S , et al....
| Keywords: | Nudifloric Acid |
| MW: | 153.14 D |
29.00€
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Toosendanin
Item number: TGM-T6S0234-10mg
Description: 1. Toosendanin possesses hepatotoxicity. 2. Toosendanin has effects on the growth, cell cycle arrest, induction of apoptosis and the involved signaling pathway in human promyelocytic leukemia HL-6 cells. 3. Toosendanin is an effective insecticide for Ae. Target: Others. Smiles:...
| MW: | 574.62 D |
From 39.00€
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Isorhynchophylline
Item number: TGM-T6S0657-2mg
Description: 1. Isorhynchophylline (7-Isorhyncophylline) and rhyncophylline can directly inhibit the contractile responses induced by several agonists in small blood vessels of rat, they also can inhibit the hypertensive effect of angiotensin II. Target: Others. Smiles:...
| Keywords: | Isorhyncophylline , IsoRhy , Isorhychophylline , 7-Isorhyncophylline |
| MW: | 384.47 D |
30.00€
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Benzoylpaeoniflorin
Item number: TGM-T6S1652-100mg
Description: 1. Benzoylpaeoniflorin is active against cyclooxygenase-1 and cyclooxygenase-2 enzymes. Target: COX, Apoptosis. Smiles: C[C@@]12C[C@@]3(O)O[C@@H](O1)[C@]1(COC(=O)c4ccccc4)[C@H]3C[C@]21O[C@@H]1O[C@H](COC(=O)c2ccccc2)[C@@H](O)[C@H](O)[C@H]1O. References: Er-Li Z , Yang L I , Hong-Yan G E . Effects of...
| MW: | 584.57 D |
From 31.00€
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Irisflorentin
Item number: TGM-T6S1665-100mg
Description: 1. Irisflorentin blocks apoptosis pathways, by exerting its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression. 2. Irisflorentin has anti-inflammatory mechanism in LPS-activated RAW 264.7 macrophages, by reducing the transcriptional and...
| MW: | 386.35 D |
From 31.00€
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Demethoxycurcumin
Item number: TGM-T6S1683-100mg
Description: 1. Demethoxycurcumin (Desmethoxycurcumin) has antioxidant activity. 2. Demethoxycurcumin has anti-inflammatory activity. 3. Demethoxycurcumin has anti-proliferative activity. 4. Demethoxycurcumin has anti-acanthamoebic effect. 5. Demethoxycurcumin is a potential additive natural product in combination...
| Keywords: | Curcumin II , Monodemethoxycurcumin , Desmethoxycurcumin |
| MW: | 338.35 D |
From 36.00€
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