JH-II-127

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-T7155-2mg	2 mg	-	-	-	7 - 10 business days*		37.00€
TGM-T7155-200mg	200 mg	-	-	-	7 - 10 business days*		546.00€

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Description: JH-II-127 is an oral inhibitor of leucine-rich repeat kinase 2 (LRRK2), targeting WT... more

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Product information "JH-II-127"

Description: JH-II-127 is an oral inhibitor of leucine-rich repeat kinase 2 (LRRK2), targeting WT LRRK2, G2019S LRRK2, and A2016T LRRK2 with IC50 values of 6.6 nM, 2.2 nM, and 47.7 nM, respectively. Target: LRRK2. Smiles: CNc1nc(Nc2ccc(cc2OC)C(=O)N2CCOCC2)nc2[nH]cc(Cl)c12. References: Discovery of a Pyrrolopyrimidine (JH-II-127), a Highly Potent, Selective, and Brain Penetrant LRRK2 Inhibitor[J]. ACS Medicinal Chemistry Letters, 2015, 6(5):584-589.

Supplier:	TargetMol
Supplier-Nr:	T7155

Properties

MW:	416.86 D
Formula:	C19H21ClN6O3

Database Information

Handling & Safety

Storage:	+4°C
Shipping:	+20°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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